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European Journal of Medical Research
Published in: European Journal of Medical Research 1/2016

Open Access 01-12-2016 | Research

How rapid is rapid? Exemplary results of real-life rapid rule-out troponin timing in troponin-positive acute coronary syndromes without persistent ST-segment elevation in two contrasting German chest pain unit facilities

Authors: Dieter Fischer, Friederike Remberg, Dirk Böse, Michael Lichtenberg, Philipp Kümpers, Pia Lebiedz, Hermann-Joseph Pavenstädt, Johannes Waltenberger, Frank Breuckmann

Published in: European Journal of Medical Research | Issue 1/2016

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Abstract

Aim

To analyse the timing of cardiac troponin (cTn) measurements in high-risk and cTn-positive acute coronary syndromes without persistent ST-segment elevation (NSTE-ACS) in two structurally different German chest pain units (CPUs), contrasting an urban university maximum care and a rural regional primary care facility.

Methods

All patients encoded as NSTEMI during the year 2013 were retrospectively enrolled in two centres: site (I)—centre of maximum care in an urban university setting and site (II)—centre of primary care in a rural regional care setting. Data acquisition included time intervals from admission to baseline cTn and first and second cTn control as well as type and timing of invasive management.

Results

The median times (site I vs. site II) from admission to cTn result announcement were 26.5 vs. 33.0 min (p = 0.02) for baseline, 4 vs. 4 h (p = 0.43) for the first and 11.0 vs. 16.5 h (p = 0.03) for the second control. Timely announcement, as recommended by guidelines, was available in 86.9 % at baseline, 59.4 % for the first or 41.1 % for the second cTn control. Rates and timing of invasive management were independent from the time point of positive cTn announcement (p = 0.51 and p = 0.68, respectively).

Conclusions

German CPUs provide timely identification of cTn-positive patients in a narrow and guideline-adherent time frame using a rapid rule-out protocol. Especially, baseline and early cTn timing was comparable between the urban university maximum care and the rural regional primary care facility without relevant impact on guideline-conforming invasive management, underlining the high standard of care in those highly professional institutions.
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Metadata
Title
How rapid is rapid? Exemplary results of real-life rapid rule-out troponin timing in troponin-positive acute coronary syndromes without persistent ST-segment elevation in two contrasting German chest pain unit facilities
Authors
Dieter Fischer
Friederike Remberg
Dirk Böse
Michael Lichtenberg
Philipp Kümpers
Pia Lebiedz
Hermann-Joseph Pavenstädt
Johannes Waltenberger
Frank Breuckmann
Publication date
01-12-2016
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 1/2016
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/s40001-016-0206-0

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