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Published in: Perioperative Medicine 1/2016

Open Access 01-12-2016 | Research

Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients

Authors: Sarka Moravcova, Bonnie Kyle, Hilary Shanahan, Savvas Giannaris, Andrew Smith, Colin Hamilton-Davies

Published in: Perioperative Medicine | Issue 1/2016

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Abstract

Background

Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery.

Methods

We examined the variability of anti-staphylococcal antibody levels across a group of healthy volunteers and compared this with patients scheduled to undergo cardiac surgery.

Results

Pre-operative cardiac surgical patients exhibited significantly higher levels of staphylococcal antibodies compared with healthy volunteers.

Conclusions

The relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation.
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Metadata
Title
Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients
Authors
Sarka Moravcova
Bonnie Kyle
Hilary Shanahan
Savvas Giannaris
Andrew Smith
Colin Hamilton-Davies
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Perioperative Medicine / Issue 1/2016
Electronic ISSN: 2047-0525
DOI
https://doi.org/10.1186/s13741-016-0039-y

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