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Addiction Science & Clinical Practice
Published in: Addiction Science & Clinical Practice 1/2015

Open Access 01-12-2015 | Review

Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders

Authors: Katherine A Belendiuk, Lisa L Baldini, Marcel O Bonn-Miller

Published in: Addiction Science & Clinical Practice | Issue 1/2015

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Abstract

The present investigation aimed to provide an objective narrative review of the existing literature pertaining to the benefits and harms of marijuana use for the treatment of the most common medical and psychological conditions for which it has been allowed at the state level. Common medical conditions for which marijuana is allowed (i.e., those conditions shared by at least 80 percent of medical marijuana states) were identified as: Alzheimer’s disease, amyotrophic lateral sclerosis, cachexia/wasting syndrome, cancer, Crohn’s disease, epilepsy and seizures, glaucoma, hepatitis C virus, human immunodeficiency virus/acquired immunodeficiency syndrome, multiple sclerosis and muscle spasticity, severe and chronic pain, and severe nausea. Post-traumatic stress disorder was also included in the review, as it is the sole psychological disorder for which medical marijuana has been allowed. Studies for this narrative review were included based on a literature search in PsycINFO, MEDLINE, and Google Scholar. Findings indicate that, for the majority of these conditions, there is insufficient evidence to support the recommendation of medical marijuana at this time. A significant amount of rigorous research is needed to definitively ascertain the potential implications of marijuana for these conditions. It is important for such work to not only examine the effects of smoked marijuana preparations, but also to compare its safety, tolerability, and efficacy in relation to existing pharmacological treatments.
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Metadata
Title
Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders
Authors
Katherine A Belendiuk
Lisa L Baldini
Marcel O Bonn-Miller
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Addiction Science & Clinical Practice / Issue 1/2015
Electronic ISSN: 1940-0640
DOI
https://doi.org/10.1186/s13722-015-0032-7

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