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Published in: Systematic Reviews 1/2019

Open Access 01-12-2019 | Gastric Cancer | Protocol

Epidemiology of gastric cancer in Africa: a systematic review and meta-analysis protocol

Authors: Celestin Danwang, Jean Joel Bigna

Published in: Systematic Reviews | Issue 1/2019

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Abstract

Background

Gastric cancer is actually known as the sixth most frequent cancer and the second cancer-related cause of death worldwide. If studies giving an overview of current epidemiology of gastric cancer in Europe, Asia, and the USA are available, in Africa, studies reporting recent data on gastric cancer are sparse. This systematic review and meta-analysis aim therefore to provide relevant data on contemporary epidemiology of gastric cancer in Africa in terms of prevalence, incidence, and case fatality rate.

Methods and design

We will include cohort, case-control, cross-sectional studies, and case series with more than 30 participants. EMBASE, PubMed, Africa Index Medicus, Africa Journals Online, and Web of Science will be searched for relevant abstracts of studies published and unpublished between January 1, 2000, and April 30, 2019, without language restriction. The review will be reported according to the MOOSE (Meta-analysis Of Observational Studies in Epidemiology) guideline. After screening of abstracts, study selection, data extraction, and risk of bias assessment, we shall assess the studies individually for clinical and statistical heterogeneity. Random-effect meta-analysis will be used to pool studies judged to be clinically homogenous. The Egger test and visual inspection of funnel plots will be used to assess publication bias.

Discussion

This review will provide relevant data on the current burden of gastric cancer in Africa.

Systematic review registration

PROSPERO CRD42019130348.
Appendix
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Metadata
Title
Epidemiology of gastric cancer in Africa: a systematic review and meta-analysis protocol
Authors
Celestin Danwang
Jean Joel Bigna
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2019
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/s13643-019-1214-2

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