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Published in: Systematic Reviews 1/2017

Open Access 01-12-2017 | Commentary

The influence of the team in conducting a systematic review

Authors: Lesley Uttley, Paul Montgomery

Published in: Systematic Reviews | Issue 1/2017

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Abstract

There is an increasing body of research documenting flaws in many published systematic reviews’ methodological and reporting conduct. When good systematic review practice is questioned, attention is rarely turned to the composition of the team that conducted the systematic review. This commentary highlights a number of relevant articles indicating how the composition of the review team could jeopardise the integrity of the systematic review study and its conclusions. Key biases require closer attention such as sponsorship bias and researcher allegiance, but there may also be less obvious affiliations in teams conducting secondary evidence-syntheses. The importance of transparency and disclosure are now firmly on the agenda for clinical trials and primary research, but the meta-biases that systematic reviews may be at risk from now require further scrutiny.
Literature
1.
go back to reference Swan, J., et al., Evidence in management decisions (EMD)—advancing knowledge utilization in healthcare management. Final Report. NIHR Health Services and Delivery Programme, 2012. Swan, J., et al., Evidence in management decisions (EMD)—advancing knowledge utilization in healthcare management. Final Report. NIHR Health Services and Delivery Programme, 2012.
3.
go back to reference Page MJ, et al. Investigation of bias in meta-analyses due to selective inclusion of trial effect estimates: empirical study. BMJ Open. 2016;6(4):e011863.CrossRefPubMedPubMedCentral Page MJ, et al. Investigation of bias in meta-analyses due to selective inclusion of trial effect estimates: empirical study. BMJ Open. 2016;6(4):e011863.CrossRefPubMedPubMedCentral
4.
go back to reference Flacco ME, et al. Head-to-head randomized trials are mostly industry sponsored and almost always favor the industry sponsor. J Clin Epidemiol. 2015;68(7):811–20.CrossRefPubMed Flacco ME, et al. Head-to-head randomized trials are mostly industry sponsored and almost always favor the industry sponsor. J Clin Epidemiol. 2015;68(7):811–20.CrossRefPubMed
6.
go back to reference Page, M.J., et al., Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions. The Cochrane Library, 2014.CrossRef Page, M.J., et al., Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions. The Cochrane Library, 2014.CrossRef
7.
go back to reference Pussegoda K, et al. Identifying approaches for assessing methodological and reporting quality of systematic reviews: a descriptive study. Systematic Reviews. 2017;6(1):117.CrossRefPubMedPubMedCentral Pussegoda K, et al. Identifying approaches for assessing methodological and reporting quality of systematic reviews: a descriptive study. Systematic Reviews. 2017;6(1):117.CrossRefPubMedPubMedCentral
9.
go back to reference Ioannidis JP. Discussion: why “an estimate of the science-wise false discovery rate and application to the top medical literature” is false. Biostatistics. 2014;15(1):28–36.CrossRefPubMed Ioannidis JP. Discussion: why “an estimate of the science-wise false discovery rate and application to the top medical literature” is false. Biostatistics. 2014;15(1):28–36.CrossRefPubMed
11.
go back to reference Munder T, et al. Researcher allegiance in psychotherapy outcome research: an overview of reviews. Clin Psychol Rev. 2013;33(4):501–11.CrossRefPubMed Munder T, et al. Researcher allegiance in psychotherapy outcome research: an overview of reviews. Clin Psychol Rev. 2013;33(4):501–11.CrossRefPubMed
12.
go back to reference Goodman S, Dickersin K. Metabias: a challenge for comparative effectiveness research. Ann Intern Med. 2011;155(1):61–2.CrossRefPubMed Goodman S, Dickersin K. Metabias: a challenge for comparative effectiveness research. Ann Intern Med. 2011;155(1):61–2.CrossRefPubMed
13.
go back to reference Elia N, et al. How do authors of systematic reviews deal with research malpractice and misconduct in original studies? A cross-sectional analysis of systematic reviews and survey of their authors. BMJ Open. 2016;6(3):e010442.CrossRefPubMedPubMedCentral Elia N, et al. How do authors of systematic reviews deal with research malpractice and misconduct in original studies? A cross-sectional analysis of systematic reviews and survey of their authors. BMJ Open. 2016;6(3):e010442.CrossRefPubMedPubMedCentral
14.
go back to reference Humaidan P, Polyzos NP. (Meta) analyze this: systematic reviews might lose credibility. Nat Med. 2012;18(9):1321.CrossRefPubMed Humaidan P, Polyzos NP. (Meta) analyze this: systematic reviews might lose credibility. Nat Med. 2012;18(9):1321.CrossRefPubMed
15.
go back to reference Borah R, et al. Analysis of the time and workers needed to conduct systematic reviews of medical interventions using data from the PROSPERO registry. BMJ Open. 2017;7(2):e012545.CrossRefPubMedPubMedCentral Borah R, et al. Analysis of the time and workers needed to conduct systematic reviews of medical interventions using data from the PROSPERO registry. BMJ Open. 2017;7(2):e012545.CrossRefPubMedPubMedCentral
16.
go back to reference Silagy CA, Middleton P, Hopewell S. Publishing protocols of systematic reviews: comparing what was done to what was planned. JAMA. 2002;287(21):2831–4.CrossRefPubMed Silagy CA, Middleton P, Hopewell S. Publishing protocols of systematic reviews: comparing what was done to what was planned. JAMA. 2002;287(21):2831–4.CrossRefPubMed
17.
18.
go back to reference Page MJ, et al. Epidemiology and reporting characteristics of systematic reviews of biomedical research: a cross-sectional study. PLoS Med. 2016:13(5). Page MJ, et al. Epidemiology and reporting characteristics of systematic reviews of biomedical research: a cross-sectional study. PLoS Med. 2016:13(5).
19.
go back to reference Moher D, et al. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement. Ann Intern Med. 2009;151(4):264–9.CrossRefPubMed Moher D, et al. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement. Ann Intern Med. 2009;151(4):264–9.CrossRefPubMed
20.
go back to reference Moher D, et al. Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) 2015 statement. Systematic reviews. 2015;4(1):1.CrossRefPubMedPubMedCentral Moher D, et al. Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) 2015 statement. Systematic reviews. 2015;4(1):1.CrossRefPubMedPubMedCentral
21.
go back to reference Wasiak, J., et al., Poor methodological quality and reporting standards of systematic reviews in burn care management. International wound journal, 2016. Wasiak, J., et al., Poor methodological quality and reporting standards of systematic reviews in burn care management. International wound journal, 2016.
22.
go back to reference Dudden RF, Protzko SL. The systematic review team: contributions of the health sciences librarian. Medical reference services quarterly. 2011;30(3):301–15.CrossRefPubMed Dudden RF, Protzko SL. The systematic review team: contributions of the health sciences librarian. Medical reference services quarterly. 2011;30(3):301–15.CrossRefPubMed
24.
go back to reference Ebrahim S, et al. Meta-analyses with industry involvement are massively published and report no caveats for antidepressants. J Clin Epidemiol. 2016;70:155–63.CrossRefPubMed Ebrahim S, et al. Meta-analyses with industry involvement are massively published and report no caveats for antidepressants. J Clin Epidemiol. 2016;70:155–63.CrossRefPubMed
25.
go back to reference Gómez-García, F., et al., Systematic reviews and meta-analyses on psoriasis: role of funding sources, conflict of interest, and bibliometric indices as predictors of methodological quality. British Journal of Dermatology, 2017. Gómez-García, F., et al., Systematic reviews and meta-analyses on psoriasis: role of funding sources, conflict of interest, and bibliometric indices as predictors of methodological quality. British Journal of Dermatology, 2017.
26.
go back to reference Bes-Rastrollo M, et al. Financial conflicts of interest and reporting bias regarding the association between sugar-sweetened beverages and weight gain: a systematic review of systematic reviews. PLoS Med. 2014;10(12):e1001578.CrossRef Bes-Rastrollo M, et al. Financial conflicts of interest and reporting bias regarding the association between sugar-sweetened beverages and weight gain: a systematic review of systematic reviews. PLoS Med. 2014;10(12):e1001578.CrossRef
27.
go back to reference Spiegelhalter D. The importance of what you don’t see. In: [Blog] Understanding Uncertainty; 2016. Spiegelhalter D. The importance of what you don’t see. In: [Blog] Understanding Uncertainty; 2016.
28.
go back to reference Eisner M, et al. Disclosure of financial conflicts of interests in interventions to improve child psychosocial health: a cross-sectional study. PLoS One. 2015;10(11):e0142803.CrossRefPubMedPubMedCentral Eisner M, et al. Disclosure of financial conflicts of interests in interventions to improve child psychosocial health: a cross-sectional study. PLoS One. 2015;10(11):e0142803.CrossRefPubMedPubMedCentral
29.
go back to reference Lieb K, et al. Conflicts of interest and spin in reviews of psychological therapies: a systematic review. BMJ Open. 2016:6(4). Lieb K, et al. Conflicts of interest and spin in reviews of psychological therapies: a systematic review. BMJ Open. 2016:6(4).
30.
go back to reference Gøtzsche PC, Ioannidis JP. Content area experts as authors: helpful or harmful for systematic reviews and meta-analyses? BMJ. 2012;345:e7031.CrossRefPubMed Gøtzsche PC, Ioannidis JP. Content area experts as authors: helpful or harmful for systematic reviews and meta-analyses? BMJ. 2012;345:e7031.CrossRefPubMed
31.
go back to reference Fleurence RL, et al. Engaging patients and stakeholders in research proposal review: the patient-centered outcomes research institute. Ann Intern Med. 2014;161(2):122–30.CrossRefPubMed Fleurence RL, et al. Engaging patients and stakeholders in research proposal review: the patient-centered outcomes research institute. Ann Intern Med. 2014;161(2):122–30.CrossRefPubMed
32.
go back to reference Basch E, et al. Methodological standards and patient-centeredness in comparative effectiveness research. JAMA-Journal of the American Medical Association. 2012;307(15):1636–40.CrossRef Basch E, et al. Methodological standards and patient-centeredness in comparative effectiveness research. JAMA-Journal of the American Medical Association. 2012;307(15):1636–40.CrossRef
33.
go back to reference Catalá-López F, et al. Global collaborative networks on meta-analyses of randomized trials published in high impact factor medical journals: a social network analysis. BMC Med. 2014;12(1):1.CrossRef Catalá-López F, et al. Global collaborative networks on meta-analyses of randomized trials published in high impact factor medical journals: a social network analysis. BMC Med. 2014;12(1):1.CrossRef
34.
go back to reference Lomas J. Using 'linkage and exchange' to move research into policy at a Canadian foundation. Health Aff. 2000;19(3):236.CrossRef Lomas J. Using 'linkage and exchange' to move research into policy at a Canadian foundation. Health Aff. 2000;19(3):236.CrossRef
35.
go back to reference Boudreau, K., et al., The novelty paradox & bias for normal science: evidence from randomized medical grant proposal evaluations. 2012. Boudreau, K., et al., The novelty paradox & bias for normal science: evidence from randomized medical grant proposal evaluations. 2012.
37.
38.
go back to reference Nasser M, et al. An equity lens can ensure an equity-oriented approach to agenda setting and priority setting of Cochrane Reviews. J Clin Epidemiol. 2013;66(5):511–21.CrossRefPubMed Nasser M, et al. An equity lens can ensure an equity-oriented approach to agenda setting and priority setting of Cochrane Reviews. J Clin Epidemiol. 2013;66(5):511–21.CrossRefPubMed
39.
41.
go back to reference Shea BJ, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007;7 Shea BJ, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007;7
42.
go back to reference Andrews J, et al. GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations. J Clin Epidemiol. 2013;66(7):719–25.CrossRefPubMed Andrews J, et al. GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations. J Clin Epidemiol. 2013;66(7):719–25.CrossRefPubMed
43.
go back to reference Guyatt GH, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ: British Medical Journal. 2008;336(7650):924.CrossRefPubMedPubMedCentral Guyatt GH, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ: British Medical Journal. 2008;336(7650):924.CrossRefPubMedPubMedCentral
44.
go back to reference Glasziou P, Djulbegovic B, Burls A. Are systematic reviews more cost-effective than randomised trials? Lancet. 2006;367(9528):2057–8.CrossRefPubMed Glasziou P, Djulbegovic B, Burls A. Are systematic reviews more cost-effective than randomised trials? Lancet. 2006;367(9528):2057–8.CrossRefPubMed
Metadata
Title
The influence of the team in conducting a systematic review
Authors
Lesley Uttley
Paul Montgomery
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2017
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/s13643-017-0548-x

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