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Systematic Reviews
Published in: Systematic Reviews 1/2017

Open Access 01-12-2017 | Systematic review update

Updated systematic review: associations between proximity to animal feeding operations and health of individuals in nearby communities

Authors: Annette M. O’Connor, Brent W. Auvermann, Rungano S. Dzikamunhenga, Julie M. Glanville, Julian P. T. Higgins, Shelley P. Kirychuk, Jan M. Sargeant, Sarah C. Totton, Hannah Wood, Susanna G. Von Essen

Published in: Systematic Reviews | Issue 1/2017

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Abstract

Objective

The objective of this review was to update a systematic review of associations between living near an animal feeding operation (AFO) and human health.

Methods

The MEDLINE® and MEDLINE® In-Process, Centre for Agricultural Biosciences Abstracts, and Science Citation Index databases were searched. Reference lists of included articles were hand-searched. Eligible studies reported exposure to an AFO and an individual-level human health outcome. Two reviewers performed study selection and data extraction.

Results

The search returned 3702 citations. Sixteen articles consisting of 10 study populations were included in the analysis. The health outcomes were lower and upper respiratory tracts, MRSA, other infectious disease, neurological, psychological, dermatological, otologic, ocular, gastrointestinal, stress and mood, and other non-infectious health outcomes. Most studies were observational and used prevalence measures of outcome. An association between Q fever risk and proximity to goat production was reported. Other associations were unclear. Risk of bias was serious or critical for most exposure-outcome associations. Multiplicity (i.e., a large number of potentially correlated outcomes and exposures assessed on the same study subjects) was common in the evidence base.

Conclusions

Few studies reported an association between surrogate clinical outcomes and AFO proximity for respiratory tract-related outcomes. There were no consistent dose-response relationships between surrogate clinical outcome and AFO proximity. A new finding was that Q fever in goats is likely associated with an increased Q fever risk in community members. The review results for the non-respiratory health outcomes were inconclusive because only a small number of studies were available or the between-study results were inconsistent.

Systematic review registration

PROSPERO CRD42014010521
Appendix
Available only for authorised users
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Metadata
Title
Updated systematic review: associations between proximity to animal feeding operations and health of individuals in nearby communities
Authors
Annette M. O’Connor
Brent W. Auvermann
Rungano S. Dzikamunhenga
Julie M. Glanville
Julian P. T. Higgins
Shelley P. Kirychuk
Jan M. Sargeant
Sarah C. Totton
Hannah Wood
Susanna G. Von Essen
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2017
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/s13643-017-0465-z

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