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Open Access 01-12-2020 | Coronavirus | Letter to the Editor

Vitamins as adjunctive treatment for coronavirus disease!

Authors: Indu Kapoor, Hemanshu Prabhakar, Charu Mahajan

Published in: Annals of Intensive Care | Issue 1/2020

Excerpt

We read with great interest the article by Li et al., where authors have reviewed many therapeutic strategies for critically ill patients with coronavirus disease (COVID-19) [1]. Apart from antiviral drugs and anti-bacterial drugs, authors also discussed various adjunctive interventions which included corticosteroids, thymosin alpha A, cyclosporine A, interferons, gamma globulins and many more. They even discussed the Chinese medicines which were used in past to treat other viral infections. They also stated that these medicines might benefit COVID-19 patients; however, the efficacy and safety of these traditional medicine formulae in COVID-19 need to be further confirmed by clinical trials. Though authors have not mentioned, another important supplementary adjunct to treat these critically ill patients in intensive care unit is various vitamins. …

Li L, Li R, Wu Z, Yang X, Zhao M, Liu J, Chen D. Therapeutic strategies for critically ill patients with COVID-19. Ann Intensive Care. 2020;10(1):45. https://doi.org/10.1186/s13613-020-00661-z.CrossRefPubMedPubMedCentral

Patel N, Penkert RR, Jones BG, Sealy RE, Surman SL, Sun Y, Tang L, DeBeauchamp J, Webb A, Richardson J, Heine R, Dallas RH, Ross AC, Webby R, Hurwitz JL. Baseline serum vitamin A and D levels determine benefit of oral vitamin A&D supplements to humoral immune responses following pediatric influenza vaccination. Viruses. 2019;11(10):907.CrossRef

Hemilä H. Vitamin C intake and susceptibility to pneumonia. Pediatric Infect Dis J. 1997;16(9):836–7.CrossRef

Kim WY, Jo EJ, Eom JS, Mok J, Kim MH, Kim KU, Park HK, Lee MK, Lee K. Combined vitamin C, hydrocortisone, and thiamine therapy for patients with severe pneumonia who were admitted to the intensive care unit: Propensity score-based analysis of a before-after cohort study. J Crit Care. 2018;47:211–8.CrossRef

Ilie PC, Stefanescu S, Smith L. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging ClinExp Res. 2020. https://doi.org/10.1007/s40520-020-01570-8.CrossRef

Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Griffiths CJ, Janssens W, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S, Stelmach I, Kumar GT, Urashima M, Camargo CA. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583.CrossRef

Title: Vitamins as adjunctive treatment for coronavirus disease!
Authors: Indu Kapoor
Hemanshu Prabhakar
Charu Mahajan
Publication date: 01-12-2020
Publisher: Springer International Publishing
Keywords: Coronavirus
COVID-19
Published in: Annals of Intensive Care / Issue 1/2020
Electronic ISSN: 2110-5820
DOI: https://doi.org/10.1186/s13613-020-00748-7

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Vitamins as adjunctive treatment for coronavirus disease!

Excerpt

At a glance: The ONWARDS insulin icodec trials

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Excerpt

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