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Published in: Annals of Intensive Care 1/2018

Open Access 01-12-2018 | Research

Impact of a VAP bundle in Belgian intensive care units

Authors: Laurent Jadot, Luc Huyghens, Annick De Jaeger, Marc Bourgeois, Dominique Biarent, Adeline Higuet, Koen de Decker, Margot Vander Laenen, Baudewijn Oosterlynck, Patrick Ferdinande, Pascal Reper, Serge Brimioulle, Sophie Van Cromphaut, Stéphane Clement De Clety, Thierry Sottiaux, Pierre Damas

Published in: Annals of Intensive Care | Issue 1/2018

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Abstract

Background

In order to decrease the incidence of ventilator-associated pneumonia (VAP) in Belgium, a national campaign for implementing a VAP bundle involving assessment of sedation, cuff pressure control, oral care with chlorhexidine and semirecumbent position, was launched in 2011–2012. This report will document the impact of this campaign.

Methods

On 1 day, once a year from 2010 till 2016, except in 2012, Belgian ICUs were questioned about their ventilated patients. For each of these, data about the application of the bundle and the possible treatment for VAP were recorded.

Results

Between 36.6 and 54.8% of the 120 Belgian ICUs participated in the successive surveys. While the characteristics of ventilated patients remained similar throughout the years, the percentage of ventilated patients and especially the duration of ventilation significantly decreased before and after the national VAP bundle campaign. Ventilator care also profoundly changed: Controlling cuff pressure, head positioning above 30° were obtained in more than 90% of cases. Oral care was more frequently performed within a day, using more concentrated solutions of chlorhexidine. Subglottic suctioning also was used but in only 24.7% of the cases in the last years. Regarding the prevalence of VAP, it significantly decreased from 28% of ventilated patients in 2010 to 10.1% in 2016 (p ≤ 0.0001).

Conclusion

Although a causal relationship cannot be inferred from these data, the successive surveys revealed a potential impact of the VAP bundle campaign on both the respiratory care of ventilated patients and the prevalence of VAP in Belgian ICUs encouraging them to follow the guidelines.
Literature
1.
go back to reference Bekaert M, Timsit JF, Vansteelandt S, et al. Outcomerea Study Group. Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis. Am J Resp Crit Care Med. 2011;184:1133–9.CrossRefPubMed Bekaert M, Timsit JF, Vansteelandt S, et al. Outcomerea Study Group. Attributable mortality of ventilator-associated pneumonia: a reappraisal using causal analysis. Am J Resp Crit Care Med. 2011;184:1133–9.CrossRefPubMed
2.
go back to reference Hutchins K, Karras G, Erwin J, Sullivan K. Ventilator-associated pneumonia and oral care: a successful quality improvement project. Am J Infect Control. 2009;37:590–7.CrossRefPubMed Hutchins K, Karras G, Erwin J, Sullivan K. Ventilator-associated pneumonia and oral care: a successful quality improvement project. Am J Infect Control. 2009;37:590–7.CrossRefPubMed
3.
go back to reference Morris AC, Hay AW, Swann DG, et al. Reducing ventilator-associated pneumonia in intensive care: impact of implementing a care bundle. Crit Care Med. 2011;39:2218–24.CrossRefPubMed Morris AC, Hay AW, Swann DG, et al. Reducing ventilator-associated pneumonia in intensive care: impact of implementing a care bundle. Crit Care Med. 2011;39:2218–24.CrossRefPubMed
4.
go back to reference Bouadma L, Mourvillier B, Deiler V, et al. A multifaceted program to prevent ventilator-associated pneumonia: impact on compliance with preventive measures. Crit Care Med. 2010;38:789–96.CrossRefPubMed Bouadma L, Mourvillier B, Deiler V, et al. A multifaceted program to prevent ventilator-associated pneumonia: impact on compliance with preventive measures. Crit Care Med. 2010;38:789–96.CrossRefPubMed
5.
go back to reference Torres A, Niederman M, Chastre J, et al. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT). Eur Respir J. 2017;50:1700582.CrossRefPubMed Torres A, Niederman M, Chastre J, et al. International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT). Eur Respir J. 2017;50:1700582.CrossRefPubMed
8.
go back to reference Reper P, Dicker D, Damas P, et al. Improving the quality of the intensive care follow-up of ventilated patients during a national registration program. Public Health. 2017;148:159–66.CrossRefPubMed Reper P, Dicker D, Damas P, et al. Improving the quality of the intensive care follow-up of ventilated patients during a national registration program. Public Health. 2017;148:159–66.CrossRefPubMed
9.
go back to reference Klompas M. Ventilator-associated pneumonia: Is zero possible? Clin Inf Dis. 2010;51:1123–6.CrossRef Klompas M. Ventilator-associated pneumonia: Is zero possible? Clin Inf Dis. 2010;51:1123–6.CrossRef
10.
11.
go back to reference Resar R, Pronovost P, Haraden C, et al. Using a bundle approach to improve ventilator care processes and reduce ventilator-associated pneumonia. Jt Comm J Qual Patient Saf. 2005;31:243–8.CrossRefPubMed Resar R, Pronovost P, Haraden C, et al. Using a bundle approach to improve ventilator care processes and reduce ventilator-associated pneumonia. Jt Comm J Qual Patient Saf. 2005;31:243–8.CrossRefPubMed
12.
go back to reference Rello J, Lode H, Cornaglia G, et al. The VAP care bundle contributors. A European care bundle for prevention of ventilator-associated pneumonia. Int Care Med. 2010;36:773–80.CrossRef Rello J, Lode H, Cornaglia G, et al. The VAP care bundle contributors. A European care bundle for prevention of ventilator-associated pneumonia. Int Care Med. 2010;36:773–80.CrossRef
13.
go back to reference Lacherade JC, De Jonghe B, Guezennec P, et al. Intermittent subglottic secretion drainage and ventilator-associated pneumonia. Am J Resp Crit Care Med. 2010;182:910–7.CrossRefPubMed Lacherade JC, De Jonghe B, Guezennec P, et al. Intermittent subglottic secretion drainage and ventilator-associated pneumonia. Am J Resp Crit Care Med. 2010;182:910–7.CrossRefPubMed
14.
go back to reference Damas P, Frippiat F, Ancion A, et al. Prevention of ventilator-associated pneumonia and ventilator-associated conditions: a randomized controlled trial with subglottic secretion suctioning. Crit Care Med. 2015;43:22–30.CrossRefPubMed Damas P, Frippiat F, Ancion A, et al. Prevention of ventilator-associated pneumonia and ventilator-associated conditions: a randomized controlled trial with subglottic secretion suctioning. Crit Care Med. 2015;43:22–30.CrossRefPubMed
15.
go back to reference Caroff D, Li L, Muscedere J, Klompas M. Subglottic secretion drainage and objective outcomes: a systematic review and meta-analysis. Crit Care Med. 2016;44:830–40.PubMed Caroff D, Li L, Muscedere J, Klompas M. Subglottic secretion drainage and objective outcomes: a systematic review and meta-analysis. Crit Care Med. 2016;44:830–40.PubMed
16.
go back to reference Koeman M, Van der Ven A, Hak E, et al. Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia. Am J Resp Crit Care Med. 2006;173:1348–55.CrossRefPubMed Koeman M, Van der Ven A, Hak E, et al. Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia. Am J Resp Crit Care Med. 2006;173:1348–55.CrossRefPubMed
17.
go back to reference Richards D. Chlorhexidine mouthwash plaque levels and gingival health. Evid Based Dent. 2017;18:37–8.CrossRefPubMed Richards D. Chlorhexidine mouthwash plaque levels and gingival health. Evid Based Dent. 2017;18:37–8.CrossRefPubMed
18.
go back to reference Klompas M, Li L, Kleinman K, et al. Associations between ventilator bundle components and outcome JAMA. Intern Med. 2016;176:1277–83. Klompas M, Li L, Kleinman K, et al. Associations between ventilator bundle components and outcome JAMA. Intern Med. 2016;176:1277–83.
20.
go back to reference Fourrier F, Cau-Pottier E, Boutigny H, et al. Effect of dental plaque antiseptic decontamination on bacterial colonization and nosocomial infection in critically ill patients. Int Care Med. 2000;26:1239–47.CrossRef Fourrier F, Cau-Pottier E, Boutigny H, et al. Effect of dental plaque antiseptic decontamination on bacterial colonization and nosocomial infection in critically ill patients. Int Care Med. 2000;26:1239–47.CrossRef
21.
go back to reference Akutsu Y, Matsubara H, Shuto K, et al. Preoperative dental brushing can reduce the risk of postoperative pneumonia in esophageal cancer patients. Surgery. 2010;147:497–502.CrossRefPubMed Akutsu Y, Matsubara H, Shuto K, et al. Preoperative dental brushing can reduce the risk of postoperative pneumonia in esophageal cancer patients. Surgery. 2010;147:497–502.CrossRefPubMed
22.
go back to reference Gu WJ, Gong YZ, Pan L, et al. Impact of oral care with versus without toothbrushing on the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis of randomized controlled trials. Crit Care. 2012;16:R90.CrossRef Gu WJ, Gong YZ, Pan L, et al. Impact of oral care with versus without toothbrushing on the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis of randomized controlled trials. Crit Care. 2012;16:R90.CrossRef
23.
go back to reference Klompas M. What is new in the prevention of nosocomial pneumonia in the ICU? Curr Opin Crit Care. 2017;23:378–84.CrossRefPubMed Klompas M. What is new in the prevention of nosocomial pneumonia in the ICU? Curr Opin Crit Care. 2017;23:378–84.CrossRefPubMed
24.
go back to reference Alvarez-Lerma F, Palomar-Martinez M, Sanchez-Garcia M, et al. Prevention of ventilator-associated pneumonia: the multimodal approach of the Spanish ICU Pneumonia Zero program. Crit Care Med. 2018;46:181–8.CrossRefPubMedPubMedCentral Alvarez-Lerma F, Palomar-Martinez M, Sanchez-Garcia M, et al. Prevention of ventilator-associated pneumonia: the multimodal approach of the Spanish ICU Pneumonia Zero program. Crit Care Med. 2018;46:181–8.CrossRefPubMedPubMedCentral
Metadata
Title
Impact of a VAP bundle in Belgian intensive care units
Authors
Laurent Jadot
Luc Huyghens
Annick De Jaeger
Marc Bourgeois
Dominique Biarent
Adeline Higuet
Koen de Decker
Margot Vander Laenen
Baudewijn Oosterlynck
Patrick Ferdinande
Pascal Reper
Serge Brimioulle
Sophie Van Cromphaut
Stéphane Clement De Clety
Thierry Sottiaux
Pierre Damas
Publication date
01-12-2018
Publisher
Springer International Publishing
Published in
Annals of Intensive Care / Issue 1/2018
Electronic ISSN: 2110-5820
DOI
https://doi.org/10.1186/s13613-018-0412-8

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