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Open Access 01-12-2016 | Editorial

Oxidative stress markers and septic acute kidney injury: Novel research avenue or road to nowhere?

Authors: Patrick M. Honore, Herbert D. Spapen

Published in: Annals of Intensive Care | Issue 1/2016

Excerpt

In this issue of Annals of Intensive care, Costa et al. reported on the association between a lower erythrocyte superoxide dismutase (SOD)1 activity and the development of acute kidney injury (AKI) in septic shock patients. At a given cutoff level, SOD1 was found to predict sepsis-induced AKI (SAKI) earlier than the classic KDIGO criteria. The authors suggested that erythrocyte SOD1 activity could act as an early marker of SAKI and, by extension, as a novel target of SAKI biomarker research [1]. The study results certainly are original and innovative, but questions arise when considering their impact. …

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Title: Oxidative stress markers and septic acute kidney injury: Novel research avenue or road to nowhere?
Authors: Patrick M. Honore
Herbert D. Spapen
Publication date: 01-12-2016
Publisher: Springer Paris
Published in: Annals of Intensive Care / Issue 1/2016
Electronic ISSN: 2110-5820
DOI: https://doi.org/10.1186/s13613-016-0201-1

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Oxidative stress markers and septic acute kidney injury: Novel research avenue or road to nowhere?

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