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Open Access 01-12-2019 | Omalizumab | Letter to the Editor

High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema

Authors: Zonne L. M. Hofman, Nikki van West, C. Erik Hack, André C. Knulst, Coen Maas, Heike Röckmann

Published in: Clinical and Translational Allergy | Issue 1/2019

Abstract

Antihistamines are the most prescribed therapy in recurrent idiopathic angioedema, yet little is known about their efficacy. Herein, we report on clinical improvement with antihistamine therapy in 120 patients evaluating angioedema attack frequency. A high incidence (36%) of antihistamine refractory cases was observed. Forty percent of patients on antihistamine prophylaxis suffered from 1 or more angioedema attacks per month. Our findings stress the need for additional treatment options for recurrent idiopathic angioedema.

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Title: High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema
Authors: Zonne L. M. Hofman
Nikki van West
C. Erik Hack
André C. Knulst
Coen Maas
Heike Röckmann
Publication date: 01-12-2019
Publisher: BioMed Central
Keywords: Omalizumab
Angioedema
Published in: Clinical and Translational Allergy / Issue 1/2019
Electronic ISSN: 2045-7022
DOI: https://doi.org/10.1186/s13601-019-0274-7

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Springer Medicine

High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema

Abstract

At a glance: The ONWARDS insulin icodec trials

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Abstract

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