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Open Access 30-10-2023 | Endometrial Cancer | Case report

Dedifferentiated endometrial carcinoma metastasis to axillary lymph node: a case report

Authors: Chase William Morrison, Kayvon Nick Sanjasaz, Saul David Nathanson, Supriya Raina-Hukku, David Matthew Pinkney, Alexis Anna Davenport

Published in: Journal of Medical Case Reports | Issue 1/2023

Abstract

Background

We present an unusual case of a left axillary lymph node metastasis from a primary dedifferentiated endometrial carcinoma. This pattern of metastasis is likely the result of circulating tumor cells reaching the node through its arterial blood supply.

Case presentation

In this report, a 68-year-old white woman with a dedifferentiated endometrial carcinoma underwent a hysterectomy. She later developed an enlarged axillary lymph node due to metastatic dedifferentiated endometrial carcinoma, treated with chemotherapy and anti-programmed cell death protein 1 immunotherapy resulting in a complete clinical and radiological response.

Conclusion

A review of the literature reveals the rarity of blood-borne lymph node metastasis, especially with uterine carcinoma. Immunotherapy has shown promising results in the treatment of some subtypes of metastatic uterine carcinoma.

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Title: Dedifferentiated endometrial carcinoma metastasis to axillary lymph node: a case report
Authors: Chase William Morrison
Kayvon Nick Sanjasaz
Saul David Nathanson
Supriya Raina-Hukku
David Matthew Pinkney
Alexis Anna Davenport
Publication date: 30-10-2023
Publisher: BioMed Central
Keywords: Endometrial Cancer
Metastasis
Endometrial Cancer
Gynecologic Cancer
Published in: Journal of Medical Case Reports / Issue 1/2023
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-023-04192-6

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Abstract

Background

Case presentation

Conclusion

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