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Published in: Journal of Medical Case Reports 1/2023

Open Access 01-12-2023 | Nephrectomy | Case report

Metanephric adenoma diagnosed on biopsy in an infant: a case report

Authors: S. Mosbahi, S. Ben Youssef, A. Zouaoui, M. Abdelali, M. Ben Fredj, N. Ben Abdejelil, S. Belhassen, S. Hidouri, I. Chabchoub, A. Ksia, L. Sahnoun, M. Mekki, A. Zakhama, A. Zrig, M. Belghith

Published in: Journal of Medical Case Reports | Issue 1/2023

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Abstract

Background

Metanephric adenoma is a rare benign renal tumor of the kidney, uncommonly observed in children. It is often misdiagnosed preoperatively as a malignant neoplasm, leading to an unnecessary nephrectomy. The challenge is to make the right diagnosis preoperatively and therefore manage it with conservative surgery. We report a case of a child with metanephric adenoma who underwent nephron-sparing surgery.

Case presentation

A renal tumor was discovered fortuitously in an 18-month-old Caucasian girl with several congenital malformations. Investigations showed a 28 × 27 × 27 mm left renal mass centrally located, well defined, nonvascularized, with no calcifications and which compressed the adjacent renal tissue. Furthermore, there were no signs of metastasis. The decision of a multidisciplinary meeting was to perform a computed tomography (CT)-scan-guided biopsy. Histologic examination concluded it was a metanephric adenoma. We performed a left open partial nephrectomy via a flank retroperitoneal incision. The final histopathological examination confirmed the diagnosis. The postoperative course was uneventful.

Conclusion

Preoperative diagnosis of metanephric adenoma is challenging. Because of the high probability of unnecessary radical nephrectomy, preoperative biopsy can be safe and determining to guide a more conservative approach so nephron-sparing surgery can be performed.
Literature
2.
go back to reference Schmelz HU, Stoschek M, Schwerer M, Danz B, Hauck EW, Weidner W, et al. Metanephric adenoma of the kidney: case report and review of the literature. Int Urol Nephrol. 2005;37:213–7.CrossRefPubMed Schmelz HU, Stoschek M, Schwerer M, Danz B, Hauck EW, Weidner W, et al. Metanephric adenoma of the kidney: case report and review of the literature. Int Urol Nephrol. 2005;37:213–7.CrossRefPubMed
3.
go back to reference Amodio JB, Shapiro E, Pinkney L. Metanephric adenoma in an 8-year-old child: case report and review of literature. J Pediatr Surg. 2005;40:25–8.CrossRef Amodio JB, Shapiro E, Pinkney L. Metanephric adenoma in an 8-year-old child: case report and review of literature. J Pediatr Surg. 2005;40:25–8.CrossRef
4.
go back to reference Netto JMB, Esteves TC, Mattos RCMS, Tibiriçá SHC, Costa SMCR, Vieira LJ. Metanephric adenoma: a rare differential diagnosis of renal tumor in children. J Ped Urol. 2007;3:340–1.CrossRef Netto JMB, Esteves TC, Mattos RCMS, Tibiriçá SHC, Costa SMCR, Vieira LJ. Metanephric adenoma: a rare differential diagnosis of renal tumor in children. J Ped Urol. 2007;3:340–1.CrossRef
5.
go back to reference Delzongle M, Boukamel S, Kemeny F, Chaaban I, Abadzhieva D, Sahnoun M, et al. Metanephric adenoma: MR imaging features with histopathological correlation. Diagn Interv Imaging. 2015;96:387–90.CrossRefPubMed Delzongle M, Boukamel S, Kemeny F, Chaaban I, Abadzhieva D, Sahnoun M, et al. Metanephric adenoma: MR imaging features with histopathological correlation. Diagn Interv Imaging. 2015;96:387–90.CrossRefPubMed
6.
go back to reference Jinzaki M, Tanimoto A, Mukai M, Ikeda E, Kobayashi S, Yuasa Y, et al. Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathologic findings and tumor angiogenesis. J Comput Assist Tomogr. 2000;24:835–42.CrossRefPubMed Jinzaki M, Tanimoto A, Mukai M, Ikeda E, Kobayashi S, Yuasa Y, et al. Double-phase helical CT of small renal parenchymal neoplasms: correlation with pathologic findings and tumor angiogenesis. J Comput Assist Tomogr. 2000;24:835–42.CrossRefPubMed
7.
go back to reference Caldwell K, Wilson J, Reyes C. Metanephric adenoma: management in a 7-year-old child. J Ped Surg Case Reports. 2015;3:570–2.CrossRef Caldwell K, Wilson J, Reyes C. Metanephric adenoma: management in a 7-year-old child. J Ped Surg Case Reports. 2015;3:570–2.CrossRef
8.
go back to reference Johnson DC, Vukina J, Smith AB, Meyer AM, Wheeler SB, Kuo TM, et al. Preoperatively misclassified, surgically removed benign renal masses: a systematic review of surgical series and United States population level burden estimate. J Urol. 2015;193(1):30–5.CrossRefPubMed Johnson DC, Vukina J, Smith AB, Meyer AM, Wheeler SB, Kuo TM, et al. Preoperatively misclassified, surgically removed benign renal masses: a systematic review of surgical series and United States population level burden estimate. J Urol. 2015;193(1):30–5.CrossRefPubMed
10.
go back to reference Rakheja D, Lian F, Tomlinson GE, Ewalt DH, Schultz RA, Margraf LR. Renal metanephric adenoma with previously unreported cytogenetic abnormalities: case report and review of the literature. Pediatr Dev Pathol. 2005;8(2):218–23.CrossRefPubMed Rakheja D, Lian F, Tomlinson GE, Ewalt DH, Schultz RA, Margraf LR. Renal metanephric adenoma with previously unreported cytogenetic abnormalities: case report and review of the literature. Pediatr Dev Pathol. 2005;8(2):218–23.CrossRefPubMed
11.
go back to reference Ding Y, Wang C, Li X, Jiang Y, Mei P, Huang W. Novel clinicopathological and molecular characterization of metanephric adenoma: a study of 28 cases. Diagn Pathol. 2018;13:54.CrossRefPubMedPubMedCentral Ding Y, Wang C, Li X, Jiang Y, Mei P, Huang W. Novel clinicopathological and molecular characterization of metanephric adenoma: a study of 28 cases. Diagn Pathol. 2018;13:54.CrossRefPubMedPubMedCentral
12.
go back to reference Le Nué R, Marcellin L, Ripepi M, Henry C, Kretz JM, Geiss S. Conservative treatment of metanephric adenoma. A case report and review of the literature. J Pediatr Urol. 2011;7(4):399–403.CrossRefPubMed Le Nué R, Marcellin L, Ripepi M, Henry C, Kretz JM, Geiss S. Conservative treatment of metanephric adenoma. A case report and review of the literature. J Pediatr Urol. 2011;7(4):399–403.CrossRefPubMed
13.
go back to reference Campbell SC, Novick AC, Belldegrun A, Blute ML, Chow GK, Derweesh IH, et al. Guideline for management of the clinical T1 renal mass. J Urol. 2009;182:1271–9.CrossRefPubMed Campbell SC, Novick AC, Belldegrun A, Blute ML, Chow GK, Derweesh IH, et al. Guideline for management of the clinical T1 renal mass. J Urol. 2009;182:1271–9.CrossRefPubMed
Metadata
Title
Metanephric adenoma diagnosed on biopsy in an infant: a case report
Authors
S. Mosbahi
S. Ben Youssef
A. Zouaoui
M. Abdelali
M. Ben Fredj
N. Ben Abdejelil
S. Belhassen
S. Hidouri
I. Chabchoub
A. Ksia
L. Sahnoun
M. Mekki
A. Zakhama
A. Zrig
M. Belghith
Publication date
01-12-2023
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2023
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-023-04046-1

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