Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Journal of Medical Case Reports
Published in: Journal of Medical Case Reports 1/2022

Open Access 01-12-2022 | Tricuspid Valve Replacement | Case report

Ablation of typical atrial flutter as therapeutic component in carcinoid heart disease: a case report

Authors: Susann Groschke, Rolf Weinert, Björn Becker, Gert Richardt, Ralph Tölg, Leon Iden, Martin Borlich

Published in: Journal of Medical Case Reports | Issue 1/2022

Login to get access

Abstract

Background

Carcinoid heart disease is the cardiac manifestation of carcinoid syndrome. There is limited research on rhythm management in patients with carcinoid heart disease. The association of typical atrial flutter and carcinoid heart disease in particular is poorly described.

Case presentation

Here we present a case of a 77-year-old German woman with carcinoid heart disease and recurrent typical atrial flutter complicating the postoperative course after tricuspid valve replacement and its successful long-term rhythm control by ablation therapy.

Conclusion

There is limited evidence on rhythm management in patients with the rare diagnosis of carcinoid heart disease. Typical atrial flutter repeatedly complicated the postoperative course of our patient with carcinoid heart disease and could finally be treated curatively by ablation. Radiofrequency ablation should be considered as a valuable therapeutic component in the challenging therapy of this disease.
Literature
1.
Jin C, et al. Carcinoid heart disease: pathophysiology, pathology, clinical manifestations, and management. Cardiology. 2021;146(1):65–73.CrossRef
2.
Kuck KH, Phan HL, Tilz RR. New ESC guidelines 2019 for the treatment of supraventricular tachycardia. Herz. 2019;44(8):701–11.CrossRef
3.
Oleinikov K, et al. Update in carcinoid heart disease—the heart of the matter. Rev Endocr Metab Disord. 2021;22:553.CrossRef
4.
Dashwood A, Rahman A, Pavicic M. Carcinoid heart disease. Eur Heart J. 2015;36(34):2326.CrossRef
5.
Thorson A, et al. Malignant carcinoid of the small intestine with metastases to the liver, valvular disease of the right side of the heart (pulmonary stenosis and tricuspid regurgitation without septal defects), peripheral vasomotor symptoms, bronchoconstriction, and an unusual type of cyanosis; a clinical and pathologic syndrome. Am Heart J. 1954;47(5):795–817.CrossRef
6.
Dobson R, et al. The clinical presentation and management of carcinoid heart disease. Int J Cardiol. 2014;173(1):29–32.CrossRef
7.
Fragkou PC, et al. Rare presentation of a metastatic pancreatic neuroendocrine neoplasm presenting with atrial flutter. Eur J Case Rep Intern Med. 2021;8(1):002216.PubMedPubMedCentral
8.
Langer C, et al. Atrial fibrillation in carcinoid heart disease: the role of serotonin. A review of the literature. Clin Res Cardiol. 2007;96(2):114–8.CrossRef
9.
Kuczma JA, Grzywa M. Broncho-pulmonary carcinoid with the cardiac arrhythmia manifestation. Pol Arch Med Wewn. 2006;116(4):971–3.PubMed
10.
11.
Shabtaie SA, et al. Catheter ablation in patients with neuroendocrine (carcinoid) tumors and carcinoid heart disease: outcomes, peri-procedural complications, and management strategies. JACC Clin Electrophysiol. 2021;7(2):151–60.CrossRef
12.
Iden L, et al. Ablation therapy as management of typical atrial flutter in the early period after cardiac surgery. Cardiol Ther. 2021;10:569.CrossRef
13.
Davar J, et al. Diagnosing and managing carcinoid heart disease in patients with neuroendocrine tumors: an expert statement. J Am Coll Cardiol. 2017;69(10):1288–304.CrossRef
14.
Wolin EM, et al. Phase III study of pasireotide long-acting release in patients with metastatic neuroendocrine tumors and carcinoid symptoms refractory to available somatostatin analogues. Drug Des Dev Ther. 2015;9:5075–86.CrossRef
15.
Maqsood MH, Tameez Ud Din A, Khan AH. Neuroendocrine tumor therapy with lutetium-177: a literature review. Cureus. 2019;11(1):e3986.PubMedPubMedCentral
Metadata
Title
Ablation of typical atrial flutter as therapeutic component in carcinoid heart disease: a case report
Authors
Susann Groschke
Rolf Weinert
Björn Becker
Gert Richardt
Ralph Tölg
Leon Iden
Martin Borlich
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2022
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-022-03251-8

Other articles of this Issue 1/2022

Journal of Medical Case Reports 1/2022 Go to the issue

Case report

Successful treatment with daratumumab, lenalidomide, and dexamethasone therapy followed by autologous stem cell transplantation for newly diagnosed polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome: a case report

Case report

Mitochondrial neurogastrointestinal encephalomyopathy in a Pakistani female: a case report 

Case report

Low apparent diffusion coefficient in an extracranial brain tumor: a case report

Case report

Corneal opacification, an atypical presentation of cystic fibrosis: a case report and review of the literature

Case report

Multisystem inflammatory syndrome in adults: a case report and review of the literature

Case report

Noma disease (cancrum oris, orofacial gangrene) in an acute myeloid leukemia patient: a case report