Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2021

Open Access 01-12-2021 | Acute Kidney Injury | Case report

Unclogging the effects of the Angiojet® thrombectomy system on kidney function: a case report

Authors: Tayeba Roper, Muhammad Amaran, Prakash Saha, Cormac Breen, David Game

Published in: Journal of Medical Case Reports | Issue 1/2021

Login to get access

Abstract

Background

AngioJet® is an increasingly used method of percutaneous mechanical thrombectomy for the treatment of patients with arterial and venous thromboses. AngioJet® has been shown to cause intravascular haemoylsis universally. We report the case of a 29 year old patient who underwent AngioJet® thrombectomy and post-procedure developed a stage 3 Acute kidney injury (AKI.) requiring renal replacement therapy (RRT), secondary to intravascular haemolysis. We aim to explore the mechanism and potential risk factors associated with developing AKI in these patients and suggest steps to optimise patient management.

Case presentation

A 29 year old Caucasian male who developed a stage 3 AKI, requiring RRT, following AngioJet® thrombectomy for an occluded femoral vein stent. Urine and laboratory investigations showed evidence of intravascular haemolysis, which was the likely cause of AKI. Following a brief period of RRT he completely recovered renal function.

Conclusions

AKI is an increasingly recognised complication following AngioJet® thrombectomy, but remains underappreciated in clinical practice. AKI results from intravascular haemolysis caused by the device. Up to 13% of patients require RRT, but overall short-term prognosis is good. Pre-procedural risk factors for the development of AKI include recent major surgery. Sodium bicarbonate should be administered to those who develop renal impairment. Renal biopsy is high risk and does not add to management. Increased clinician awareness and vigilance for AKI post-procedure can allow for early recognition and referral to nephrology services for ongoing management.
Literature
1.
go back to reference Garcia MJ, et al. Endovascular management of deep vein thrombosis with rheolytic thrombectomy: final report of the prospective multicenter PEARL (Peripheral Use of AngioJet Rheolytic Thrombectomy with a Variety of Catheter Lengths) Registry. J Vasc Interv Radiol. 2015;26(6):777–85 (quiz 786).CrossRef Garcia MJ, et al. Endovascular management of deep vein thrombosis with rheolytic thrombectomy: final report of the prospective multicenter PEARL (Peripheral Use of AngioJet Rheolytic Thrombectomy with a Variety of Catheter Lengths) Registry. J Vasc Interv Radiol. 2015;26(6):777–85 (quiz 786).CrossRef
2.
go back to reference Lin PH, et al. Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis. Am J Surg. 2006;192(6):782–8.CrossRef Lin PH, et al. Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis. Am J Surg. 2006;192(6):782–8.CrossRef
3.
go back to reference Sharafuddin MJA, Hicks ME. Current status of percutaneous mechanical thrombectomy part ii devices and mechanisms of action. J Vasc Int Radiol. 1998;9(1):15–31.CrossRef Sharafuddin MJA, Hicks ME. Current status of percutaneous mechanical thrombectomy part ii devices and mechanisms of action. J Vasc Int Radiol. 1998;9(1):15–31.CrossRef
4.
go back to reference Arslan B, Turba UC, Matsumoto AH. Acute renal failure associated with percutaneous mechanical thrombectomy for iliocaval venous thrombosis. Semin Intervent Radiol. 2007;24(3):288–95.CrossRef Arslan B, Turba UC, Matsumoto AH. Acute renal failure associated with percutaneous mechanical thrombectomy for iliocaval venous thrombosis. Semin Intervent Radiol. 2007;24(3):288–95.CrossRef
5.
go back to reference Dukkipati R, et al. Acute kidney injury caused by intravascular hemolysis after mechanical thrombectomy. Nat Clin Pract Nephrol. 2009;5(2):112–6.CrossRef Dukkipati R, et al. Acute kidney injury caused by intravascular hemolysis after mechanical thrombectomy. Nat Clin Pract Nephrol. 2009;5(2):112–6.CrossRef
6.
go back to reference Bedi P, et al. Acute kidney injury requiring renal replacement therapy due to severe hemolysis after mechanical thrombectomy. Case Rep Intern Med. 2016;3(4):87–90. Bedi P, et al. Acute kidney injury requiring renal replacement therapy due to severe hemolysis after mechanical thrombectomy. Case Rep Intern Med. 2016;3(4):87–90.
7.
go back to reference Esteras R, et al. Podocyte and tubular involvement in AngioJet-induced kidney injury. Clin Kidney J. 2019;14:424.CrossRef Esteras R, et al. Podocyte and tubular involvement in AngioJet-induced kidney injury. Clin Kidney J. 2019;14:424.CrossRef
8.
go back to reference Hultin S. AngioJetTM rheolytic thrombectomy induced intravascular haemolysis leading to Acute Kidney Injury requiring Dialysis. J Clin Nephrol. 2018;2:025–8.CrossRef Hultin S. AngioJetTM rheolytic thrombectomy induced intravascular haemolysis leading to Acute Kidney Injury requiring Dialysis. J Clin Nephrol. 2018;2:025–8.CrossRef
9.
go back to reference Mehta RL, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11(2):R31.CrossRef Mehta RL, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11(2):R31.CrossRef
10.
go back to reference Dvanajscak Z, et al. Hemolysis-associated hemoglobin cast nephropathy results from a range of clinicopathologic disorders. Kidney Int. 2019;96(6):1400–7.CrossRef Dvanajscak Z, et al. Hemolysis-associated hemoglobin cast nephropathy results from a range of clinicopathologic disorders. Kidney Int. 2019;96(6):1400–7.CrossRef
11.
go back to reference Shen Y, et al. Increased risk of acute kidney injury with percutaneous mechanical thrombectomy using AngioJet compared with catheter-directed thrombolysis. J Vasc Surg Venous Lymphat Disord. 2019;7(1):29–37.CrossRef Shen Y, et al. Increased risk of acute kidney injury with percutaneous mechanical thrombectomy using AngioJet compared with catheter-directed thrombolysis. J Vasc Surg Venous Lymphat Disord. 2019;7(1):29–37.CrossRef
12.
go back to reference Moledina DG, et al. Kidney biopsy-related complications in hospitalized patients with acute kidney disease. Clin J Am Soc Nephrol. 2018;13(11):1633–40.CrossRef Moledina DG, et al. Kidney biopsy-related complications in hospitalized patients with acute kidney disease. Clin J Am Soc Nephrol. 2018;13(11):1633–40.CrossRef
13.
go back to reference Van Avondt K, Nur E, Zeerleder S. Mechanisms of haemolysis-induced kidney injury. Nat Rev Nephrol. 2019;15(11):671–92.CrossRef Van Avondt K, Nur E, Zeerleder S. Mechanisms of haemolysis-induced kidney injury. Nat Rev Nephrol. 2019;15(11):671–92.CrossRef
14.
go back to reference Leung DA, et al. Rheolytic pharmacomechanical thrombectomy for the management of acute limb ischemia: results from the PEARL registry. J Endovasc Ther. 2015;22(4):546–57.CrossRef Leung DA, et al. Rheolytic pharmacomechanical thrombectomy for the management of acute limb ischemia: results from the PEARL registry. J Endovasc Ther. 2015;22(4):546–57.CrossRef
15.
go back to reference Morrow KL, et al. Increased risk of renal dysfunction with percutaneous mechanical thrombectomy compared with catheter-directed thrombolysis. J Vasc Surg. 2017;65(5):1460–6.CrossRef Morrow KL, et al. Increased risk of renal dysfunction with percutaneous mechanical thrombectomy compared with catheter-directed thrombolysis. J Vasc Surg. 2017;65(5):1460–6.CrossRef
16.
go back to reference Escobar GA, et al. Risk of acute kidney injury after percutaneous pharmacomechanical thrombectomy using AngioJet in venous and arterial thrombosis. Ann Vasc Surg. 2017;42:238–45.CrossRef Escobar GA, et al. Risk of acute kidney injury after percutaneous pharmacomechanical thrombectomy using AngioJet in venous and arterial thrombosis. Ann Vasc Surg. 2017;42:238–45.CrossRef
Metadata
Title
Unclogging the effects of the Angiojet® thrombectomy system on kidney function: a case report
Authors
Tayeba Roper
Muhammad Amaran
Prakash Saha
Cormac Breen
David Game
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2021
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-021-03062-3

Other articles of this Issue 1/2021

Journal of Medical Case Reports 1/2021 Go to the issue