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Published in: Journal of Medical Case Reports 1/2020

Open Access 01-12-2020 | Musculoskeletal Pain | Case report

Scurvy may occur even in children with no underlying risk factors: a case report

Authors: Romina Gallizzi, Mariella Valenzise, Stefano Passanisi, Giovanni Battista Pajno, Filippo De Luca, Giuseppina Zirilli

Published in: Journal of Medical Case Reports | Issue 1/2020

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Abstract

Background

Since ancient times, scurvy has been considered one of the most fearsome nutritional deficiency diseases. In modern developed countries, this condition has become very rare and is only occasionally encountered, especially in the pediatric population. Underlying medical conditions, such as neuropsychiatric disorders, anorexia nervosa, celiac disease, Crohn disease, hemodialysis, and severe allergies to food products may enhance the risk of developing scurvy.

Case presentation

We report the case of an otherwise healthy 3-year-old white boy who developed scurvy due to a selective restrictive diet derived from his refusal to try new food. He presented to our clinic with asthenia and refusal to walk. During hospitalization he developed severe anemia and hematochezia. A diagnosis of scurvy was assessed on the basis of nutritional history, clinical features, radiographic findings, and laboratory findings. Supplementation of ascorbic acid enabled a prompt resolution of symptoms.

Conclusions

Scurvy is caused by vitamin C deficiency. Cutaneous bleeding, mucosal bleeding, and anemia represent typical manifestations of the disease. These symptoms are directly connected to ascorbic acid involvement in collagen biosynthesis. Some radiographic findings can be useful for the diagnosis. Treatment aims to normalize serum levels of vitamin C in order to counteract the deprivation symptoms. The present case report demonstrates that scurvy may sporadically occur in pediatric patients, even in individuals with no predisposing medical conditions and/or potential risk factors.
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Metadata
Title
Scurvy may occur even in children with no underlying risk factors: a case report
Authors
Romina Gallizzi
Mariella Valenzise
Stefano Passanisi
Giovanni Battista Pajno
Filippo De Luca
Giuseppina Zirilli
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2020
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-020-2341-z

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