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Published in: Journal of Medical Case Reports 1/2020

01-12-2020 | Wound Debridement | Case report

Using a combination therapy to combat scalp necrosis: a case report

Authors: Kazem Hajmohammadi, Roghayeh Esmaeili Zabihi, Kamran Akbarzadeh, Naser Parizad

Published in: Journal of Medical Case Reports | Issue 1/2020

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Abstract

Background

Chronic nonhealing wounds are very expensive to treat and debilitating, and they reduce health-related quality of life. Scalp necrosis is very rare due to its rich vascularity. However, any post-traumatic wounds with secondary infection can lead to scalp necrosis.

Case presentation

We report a case of a 77-year-old Azerbaijani man with a history of diabetes who had a car accident and sustained a scalp wound. He underwent reconstructive surgery for the scalp wound. The wound became infected, and scalp necrosis developed following the surgery. There was no progress in wound healing in spite of conventional wound therapy. We combined maggot debridement therapy with negative-pressure wound therapy and amniotic membrane grafting for 7 months. Necrotic tissues began to be eliminated after the second use of larva therapy, and the wound became free of necrotic tissues with clear increase of granulated tissues after four treatments with maggot debridement therapy. Then, we applied negative-pressure wound therapy and amniotic membrane grafting to accelerate wound healing and improve wound closure. The patient’s scalp wound recovered well, and he was discharged to home in good condition.

Conclusions

Medical and wound care teams can benefit from this combination therapy when dealing with nonhealing necrotic wounds.
Literature
2.
go back to reference Anderson K, Hamm RL. Factors that impair wound healing. J Am Coll Clin Wound Spec. 2012;4(4):84–91.PubMedCrossRef Anderson K, Hamm RL. Factors that impair wound healing. J Am Coll Clin Wound Spec. 2012;4(4):84–91.PubMedCrossRef
3.
go back to reference Naik G, Harding KG. Maggot debridement therapy: the current perspectives. Chronic Wound Care Manag Res. 2017;4:121–8.CrossRef Naik G, Harding KG. Maggot debridement therapy: the current perspectives. Chronic Wound Care Manag Res. 2017;4:121–8.CrossRef
4.
go back to reference Mudge E, Price P, Neal W, Harding KG. A randomized controlled trial of larval therapy for the debridement of leg ulcers: results of a multicenter, randomized, controlled, open, observer blind, parallel group study. Wound Repair Regen. 2014;22(1):43–51.PubMedCrossRef Mudge E, Price P, Neal W, Harding KG. A randomized controlled trial of larval therapy for the debridement of leg ulcers: results of a multicenter, randomized, controlled, open, observer blind, parallel group study. Wound Repair Regen. 2014;22(1):43–51.PubMedCrossRef
5.
go back to reference Baer WS. The treatment of chronic osteomyelitis with the maggot (larva of the bow fly). J Bone Joint Surg. 1931;13(3):438–75. Baer WS. The treatment of chronic osteomyelitis with the maggot (larva of the bow fly). J Bone Joint Surg. 1931;13(3):438–75.
6.
go back to reference Pettican A, Baptista C. Maggot debridement therapy and its role in chronic wound management. Singapore Nurs J. 2012;39(1):27–33. Pettican A, Baptista C. Maggot debridement therapy and its role in chronic wound management. Singapore Nurs J. 2012;39(1):27–33.
7.
go back to reference Zhang J, Hu ZC, Chen D, Guo D, Zhu JY, Tang B. Effectiveness and safety of negative-pressure wound therapy for diabetic foot ulcers: a meta-analysis. Plast Reconstr Surg. 2014;134(1):141–51.PubMedCrossRef Zhang J, Hu ZC, Chen D, Guo D, Zhu JY, Tang B. Effectiveness and safety of negative-pressure wound therapy for diabetic foot ulcers: a meta-analysis. Plast Reconstr Surg. 2014;134(1):141–51.PubMedCrossRef
8.
go back to reference Zelen CM, Gould L, Serena TE, Carter MJ, Keller J, Li WW. A prospective, randomised, controlled, multi-centre comparative effectiveness study of healing using dehydrated human amnion/chorion membrane allograft, bioengineered skin substitute or standard of care for treatment of chronic lower extremity diabetic ulcers. Int Wound J. 2015;12(6):724–32. https://doi.org/10.1111/iwj.12395.PubMedCrossRef Zelen CM, Gould L, Serena TE, Carter MJ, Keller J, Li WW. A prospective, randomised, controlled, multi-centre comparative effectiveness study of healing using dehydrated human amnion/chorion membrane allograft, bioengineered skin substitute or standard of care for treatment of chronic lower extremity diabetic ulcers. Int Wound J. 2015;12(6):724–32. https://​doi.​org/​10.​1111/​iwj.​12395.PubMedCrossRef
9.
go back to reference Forbes J, Fetterolf D. Dehydrated amniotic membrane allografts for the treatment of chronic wounds: a case series. J Wound Care. 2012;21(6):290–6.PubMedCrossRef Forbes J, Fetterolf D. Dehydrated amniotic membrane allografts for the treatment of chronic wounds: a case series. J Wound Care. 2012;21(6):290–6.PubMedCrossRef
10.
go back to reference Hajimohammad K, Esmaili R, Rahimi Z. Maggot debridement therapy for diabetic foot ulcer: a case report. J Crit Care Nurs. 2017;10(3):e9836.CrossRef Hajimohammad K, Esmaili R, Rahimi Z. Maggot debridement therapy for diabetic foot ulcer: a case report. J Crit Care Nurs. 2017;10(3):e9836.CrossRef
11.
go back to reference Arti H, Khorami M, Ebrahimi-Nejad V. Comparison of negative pressure wound therapy (NPWT) & conventional wound dressings in the open fracture wounds. Pak J Med Sci. 2016;32(1):65–9.PubMedPubMedCentral Arti H, Khorami M, Ebrahimi-Nejad V. Comparison of negative pressure wound therapy (NPWT) & conventional wound dressings in the open fracture wounds. Pak J Med Sci. 2016;32(1):65–9.PubMedPubMedCentral
12.
go back to reference Dehghani M, Azarpira N, Karimi VM, Mossayebi H, Esfandiari E. Grafting with cryopreserved amniotic membrane versus conservative wound care in treatment of pressure ulcers: a randomized clinical trial. Bull Emerg Trauma. 2017;5(4):249–58.PubMedPubMedCentralCrossRef Dehghani M, Azarpira N, Karimi VM, Mossayebi H, Esfandiari E. Grafting with cryopreserved amniotic membrane versus conservative wound care in treatment of pressure ulcers: a randomized clinical trial. Bull Emerg Trauma. 2017;5(4):249–58.PubMedPubMedCentralCrossRef
13.
go back to reference Kumar A, Sinha S, Mahapatra AK. Post-traumatic infection induced scalp necrosis – an unusual complication. Indian J Neurotrauma. 2012;9(1):62–3.CrossRef Kumar A, Sinha S, Mahapatra AK. Post-traumatic infection induced scalp necrosis – an unusual complication. Indian J Neurotrauma. 2012;9(1):62–3.CrossRef
14.
go back to reference Sun X, Jiang K, Chen J, et al. A systematic review of maggot debridement therapy for chronically infected wounds and ulcers. Int J Infect Dis. 2014;25:32–7.PubMedCrossRef Sun X, Jiang K, Chen J, et al. A systematic review of maggot debridement therapy for chronically infected wounds and ulcers. Int J Infect Dis. 2014;25:32–7.PubMedCrossRef
15.
go back to reference Brown A, Horobin A, Blount D, et al. Blow fly Lucilia sericata nuclease digests DNA associated with wound slough/eschar and with Pseudomonas aeruginosa biofilm. Med Vet Entomol. 2012;26(4):432–9.PubMedCrossRef Brown A, Horobin A, Blount D, et al. Blow fly Lucilia sericata nuclease digests DNA associated with wound slough/eschar and with Pseudomonas aeruginosa biofilm. Med Vet Entomol. 2012;26(4):432–9.PubMedCrossRef
16.
go back to reference Van Der Plas MJ, Andersen AS, Nazir S, et al. A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. PLoS One. 2014;9(3):e92096.PubMedPubMedCentralCrossRef Van Der Plas MJ, Andersen AS, Nazir S, et al. A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. PLoS One. 2014;9(3):e92096.PubMedPubMedCentralCrossRef
17.
go back to reference Futrega K, King M, Lott WB, Doran MR. Treating the whole not the hole: necessary coupling of technologies for diabetic foot ulcer treatment. Trends Mol Med. 2014;20(3):137–42.PubMedCrossRef Futrega K, King M, Lott WB, Doran MR. Treating the whole not the hole: necessary coupling of technologies for diabetic foot ulcer treatment. Trends Mol Med. 2014;20(3):137–42.PubMedCrossRef
18.
go back to reference Liu S, He C, Cai Y, et al. Evaluation of negative-pressure wound therapy for patients with diabetic foot ulcers: systematic review and meta-analysis. Ther Clin Risk Manag. 2017;13:533.PubMedPubMedCentralCrossRef Liu S, He C, Cai Y, et al. Evaluation of negative-pressure wound therapy for patients with diabetic foot ulcers: systematic review and meta-analysis. Ther Clin Risk Manag. 2017;13:533.PubMedPubMedCentralCrossRef
19.
go back to reference Potula VS. Conventional treatment versus vacuum therapy for diabetic foot ulcers treatment. Int J Surg. 2017;5(1):49–53.CrossRef Potula VS. Conventional treatment versus vacuum therapy for diabetic foot ulcers treatment. Int J Surg. 2017;5(1):49–53.CrossRef
20.
go back to reference Koob TJ, Lim JJ, Massee M, Zabek N, Denoziere G. Properties of dehydrated human amnion/chorion composite grafts: implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353–62.PubMedCrossRef Koob TJ, Lim JJ, Massee M, Zabek N, Denoziere G. Properties of dehydrated human amnion/chorion composite grafts: implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353–62.PubMedCrossRef
Metadata
Title
Using a combination therapy to combat scalp necrosis: a case report
Authors
Kazem Hajmohammadi
Roghayeh Esmaeili Zabihi
Kamran Akbarzadeh
Naser Parizad
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2020
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-020-02450-5

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