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Published in: Journal of Medical Case Reports 1/2017

Open Access 01-12-2017 | Case report

Fluorodeoxyglucose-positron emission tomography/computed tomography imaging features of colloid adenocarcinoma of the lung: a case report

Authors: ZhenGuang Wang, MingMing Yu, YueHua Chen, Yan Kong

Published in: Journal of Medical Case Reports | Issue 1/2017

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Abstract

Background

Colloid adenocarcinoma of the lung is a rare subtype of variants of invasive adenocarcinomas. We report the appearance of this unusual entity on 18F-fluorodeoxyglucose positron emission tomography/computed tomography.

Case presentation

A 60-year-old man of Chinese Han nationality coughed with a little white sputum for 1 month. Chest computed tomography showed multiple bilateral subpleural nodules and plaques accompanied by air bronchograms, which were most concentrated in the lower lobe of his right lung. Positron emission tomography indicated increased radioactivity uptake with a maximum standardized uptake value of 3.5. Positron emission tomography/computed tomography showed a soft tissue density lesion in his left adrenal gland with a maximum standardized uptake value of 4.1. The positron emission tomography/computed tomography appearance suggested a primary colloid adenocarcinoma in the lower lobe of his right lung accompanied by intrapulmonary and left adrenal gland metastases. The diagnostic rate of colloid adenocarcinoma can be increased by combining the anatomic and metabolic information of lesions.

Conclusions

The advantage of positron emission tomography/computed tomography in the diagnosis of colloid adenocarcinoma, as with other cancers, is the ability to locate extrapulmonary disease, facilitating clinical staging.
Literature
1.
go back to reference Zugazagoitia J, Enguita AB, Nuñez JA, Iglesias L, Ponce S. The new IASLC/ATS/ERS lung adenocarcinoma classification from a clinical perspective: current concepts and future prospects. J Thorac Dis. 2014;6 Suppl 5:S526–36.PubMedPubMedCentral Zugazagoitia J, Enguita AB, Nuñez JA, Iglesias L, Ponce S. The new IASLC/ATS/ERS lung adenocarcinoma classification from a clinical perspective: current concepts and future prospects. J Thorac Dis. 2014;6 Suppl 5:S526–36.PubMedPubMedCentral
2.
go back to reference Rossi G, Murer B, Cavazza A, Losi L, Natali P, Marchioni A, Migaldi M, Capitanio G, Brambilla E. Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression. Am J Surg Pathol. 2004;28(4):442–52.CrossRefPubMed Rossi G, Murer B, Cavazza A, Losi L, Natali P, Marchioni A, Migaldi M, Capitanio G, Brambilla E. Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression. Am J Surg Pathol. 2004;28(4):442–52.CrossRefPubMed
3.
go back to reference Russell PA, Wainer Z, Wright GM, Daniels M, Conron M, Williams RA. Does lung adenocarcinoma subtype predict patient survival?: A clinicopathologic study based on the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary lung adenocarcinoma classification. J Thorac Oncol. 2011;6(9):1496–504.CrossRefPubMed Russell PA, Wainer Z, Wright GM, Daniels M, Conron M, Williams RA. Does lung adenocarcinoma subtype predict patient survival?: A clinicopathologic study based on the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary lung adenocarcinoma classification. J Thorac Oncol. 2011;6(9):1496–504.CrossRefPubMed
4.
go back to reference Ming M, Wang ZG, Li D, Wu F, Liu S, Shi B, Xue W. The applications of corrected standardized uptake values in the diagnosis of peripheral lung lesions. Medicine (Baltimore). 2015;94(6):e531.CrossRef Ming M, Wang ZG, Li D, Wu F, Liu S, Shi B, Xue W. The applications of corrected standardized uptake values in the diagnosis of peripheral lung lesions. Medicine (Baltimore). 2015;94(6):e531.CrossRef
5.
go back to reference Clayton F. Bronchioloalveolar carcinomas. Cell types, patterns of growth, and prognostic correlates. Cancer. 1986;57(8):1555–64.CrossRefPubMed Clayton F. Bronchioloalveolar carcinomas. Cell types, patterns of growth, and prognostic correlates. Cancer. 1986;57(8):1555–64.CrossRefPubMed
6.
go back to reference Sawada E, Nambu A, Motosugi U, Araki T, Kato S, Sato Y, Saito A, Ishihara H, Okuwaki H, Ozawa K, Nishikawa K, Miyazawa M, Miyata K. Localized mucinous bronchioloalveolar carcinoma of the lung: thin-section computed tomography and fluorodeoxyglucose positron emission tomography findings. Jpn J Radiol. 2010;28(4):251–8.CrossRefPubMed Sawada E, Nambu A, Motosugi U, Araki T, Kato S, Sato Y, Saito A, Ishihara H, Okuwaki H, Ozawa K, Nishikawa K, Miyazawa M, Miyata K. Localized mucinous bronchioloalveolar carcinoma of the lung: thin-section computed tomography and fluorodeoxyglucose positron emission tomography findings. Jpn J Radiol. 2010;28(4):251–8.CrossRefPubMed
7.
go back to reference Oda S, Awai K, Liu D, Nakaura T, Yanaga Y, Nomori H, Yamashita Y. Ground-glass opacities on thin-section helical CT: differentiation between bronchioloalveolar carcinoma and atypical adenomatous hyperplasia. AJR Am J Roentgenol. 2008;190(5):1363–8.CrossRefPubMed Oda S, Awai K, Liu D, Nakaura T, Yanaga Y, Nomori H, Yamashita Y. Ground-glass opacities on thin-section helical CT: differentiation between bronchioloalveolar carcinoma and atypical adenomatous hyperplasia. AJR Am J Roentgenol. 2008;190(5):1363–8.CrossRefPubMed
8.
go back to reference Sung YM, Lee KS, Kim BT, Han J, Lee EJ. Lobar mucinous bronchioloalveolar carcinoma of the lung showing negative FDG uptake on integrated PET/CT. Eur Radiol. 2005;15(10):2075–8.CrossRefPubMed Sung YM, Lee KS, Kim BT, Han J, Lee EJ. Lobar mucinous bronchioloalveolar carcinoma of the lung showing negative FDG uptake on integrated PET/CT. Eur Radiol. 2005;15(10):2075–8.CrossRefPubMed
9.
go back to reference Tateishi U, Müller NL, Johkoh T, Maeshima A, Asamura H, Satake M, Kusumoto M, Arai Y. Mucin-producing adenocarcinoma of the lung: thin-section computed tomography findings in 48 patients and their effect on prognosis. J Comput Assist Tomogr. 2005;29(3):361–8.CrossRefPubMed Tateishi U, Müller NL, Johkoh T, Maeshima A, Asamura H, Satake M, Kusumoto M, Arai Y. Mucin-producing adenocarcinoma of the lung: thin-section computed tomography findings in 48 patients and their effect on prognosis. J Comput Assist Tomogr. 2005;29(3):361–8.CrossRefPubMed
10.
go back to reference Gaeta M, Blandino A, Pergolizzi S, Mazziotti S, Caruso R, Barone M, Cascinu S. Patterns of recurrence of bronchioloalveolar cell carcinoma after surgical resection: a radiological, histological, and immunohistochemical study. Lung Cancer. 2003;42(3):319–3.CrossRefPubMed Gaeta M, Blandino A, Pergolizzi S, Mazziotti S, Caruso R, Barone M, Cascinu S. Patterns of recurrence of bronchioloalveolar cell carcinoma after surgical resection: a radiological, histological, and immunohistochemical study. Lung Cancer. 2003;42(3):319–3.CrossRefPubMed
11.
go back to reference Oka S, Hanagiri T, Uramoto H, Baba T, Takenaka M, Yasuda M, Ono K, So T, Takenoyama M, Yasumoto K. Surgical resection for patients with mucinous bronchioloalveolar carcinoma. Asian J Surg. 2010;33(2):89–93.CrossRefPubMed Oka S, Hanagiri T, Uramoto H, Baba T, Takenaka M, Yasuda M, Ono K, So T, Takenoyama M, Yasumoto K. Surgical resection for patients with mucinous bronchioloalveolar carcinoma. Asian J Surg. 2010;33(2):89–93.CrossRefPubMed
Metadata
Title
Fluorodeoxyglucose-positron emission tomography/computed tomography imaging features of colloid adenocarcinoma of the lung: a case report
Authors
ZhenGuang Wang
MingMing Yu
YueHua Chen
Yan Kong
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2017
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-017-1380-6

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