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Journal of Medical Case Reports

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Open Access 01-12-2015 | Case report

Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature

Authors: Jihane Khalil, Mohamed Afif, Hanan Elkacemi, Meryem Benoulaid, Tayeb Kebdani, Noureddine Benjaafar

Published in: Journal of Medical Case Reports | Issue 1/2015

Abstract

Introduction

Neurofibromatosis type 1, also known as Von Recklinghausen’s disease, is a rare neuroectodermal disease that mainly affects the skin and the nervous system. Patients with neurofibromatosis type 1 have a higher risk of developing various types of cancers, especially tumors derived from the embryogenic neural crest. However, its association with breast cancer has seldom been reported.

Case presentation

We report the cases of three white Arabic women diagnosed with neurofibromatosis type 1, with a median age of 40-years-old (range: 39 to 43), who sought treatment at our centre for breast cancer.

Conclusions

The association between neurofibromatosis type 1 and breast cancer is uncommon. In our case series we readdress this association through a literature review.

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Title: Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature
Authors: Jihane Khalil
Mohamed Afif
Hanan Elkacemi
Meryem Benoulaid
Tayeb Kebdani
Noureddine Benjaafar
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2015
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-015-0533-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Breast cancer associated with neurofibromatosis type 1: a case series and review of the literature

Abstract

Introduction

Case presentation

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusions

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