Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Trials
Published in: Trials 1/2016

Open Access 01-12-2016 | Study protocol

Comparing the effectiveness of the BPMAP (Blood Pressure Management Application) and usual care in self-management of primary hypertension and adherence to treatment in patients aged 30–60 years: study protocol for a randomized controlled trial

Authors: Mahnaz Ashoorkhani, Ali Bozorgi, Reza Majdzadeh, Hamed Hosseini, Ali Yoonessi, Ali Ramezankhani, Hassan Eftekhar

Published in: Trials | Issue 1/2016

Login to get access

Abstract

Background

Hypertension is one of the most important and well-known risk factors for cardiovascular diseases. Unfortunately, in spite of effective treatments, adherence to the regular use of drugs and other nondrug treatments, such as lifestyle improvement, is often poor. This study evaluates the effectiveness of an educational, supportive intervention – in the form of a Blood Pressure Management Application (BPMAP) – on self-management in patients with primary hypertension on controlling the determinant factors of hypertension, and on adherence to treatment.

Methods/design

A two-arm, parallel-design randomized controlled clinical trial will be conducted on 30 to 60 year-old patients with primary hypertension who are attending the Tehran Heart Center. One hundred and thirty-two (132) patients will be randomly assigned to the intervention and control (usual method) groups. The most important inclusion criteria are, having primary hypertension and being pharmacologically treated for it, and not having developed the complications of hypertension, such as myocardial infarction, cerebral stroke and cardiac insufficiency. The participants should be able to read Persian and be able to use the application.
The most important outcomes of the study include adherence to treatment, weight control, and regular monitoring of blood pressure which are assessed in the primary assessment (baseline data questionnaire) and again at the 8th and 24th weeks. The intervention is a mobile application that has capabilities such as reminders and scientific and supportive information.

Discussion

This application has been programmed to reduce many of the nonadherence factors of hypertension treatment. Therefore, the findings may contribute to a rise in adherence to treatment. If proven to have an appropriate impact, it may be extended for use in the national hypertension control plan.

Trial registration

This study was registered in the Iran Randomized Clinical Trial Center under the number IRCT201511171221​1N2 on 1 January 2016.
Appendix
Available only for authorised users
Literature
1.
Raghu A, Devarsetty P, Peiris D, Clifford G, Tarassenko L. Engineering a mobile health tool for resource-poor settings to assess and manage cardiovascular disease risk: SMARThealth study. BMC Med Inform Decis Mak. 2013;15:1–15.
2.
Bolaji A. Simulation of a real-time mobile health monitoring system model for hypertensive patient in rural Nigeria. Afr J Comp ICT. 2014;7:95–100.
3.
James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, Lackland DT, LeFevre ML, MacKenzie TD, Ogedegbe O. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311:507–20.CrossRefPubMed
4.
Kahana S, Drotar D, Frazier T. Meta-analysis of psychological interventions to promote adherence to treatment in pediatric chronic health conditions. J Pediatr Psychol. 2008;33:590–611.CrossRefPubMed
5.
Martínez-Pérez B, de la Torre-Díez I, López-Coronado M, Herreros-González J. Mobile apps in cardiology: review. JMIR mHealth and uHealth. 2013; doi:10.​2196/​mhealth.​2737.
6.
Jones V, Gay V, Leijdekkers P. Body sensor networks for mobile health monitoring: Experience in europe and australia. In Digital Society, 2010 ICDS'10 Fourth International Conference on. IEEE; 2010:204-9.
7.
Honeyman E, Ding H, Varnfield M, Karunanithi M. Mobile health applications in cardiac care. Interv Cardiol. 2014;6:227–40.CrossRef
8.
9.
Kim MT, Hill MN, Bone LR, Levine DM. Development and testing of the Hill‐Bone Compliance to High Blood Pressure Therapy Scale. Prog Cardiovasc Nurs. 2000;15:90–6.CrossRefPubMed
10.
Song Y, Han H-R, Song H-J, Nam S, Nguyen T, Kim MT. Psychometric evaluation of Hill-Bone Medication Adherence Subscale. Asian Nurs Res. 2011;5:183–8.CrossRef
11.
Dehghan M, Nayeri ND, Iranmanesh S. Validating the Persian version of the Hill-Bone’s Scale of “Compliance to High Blood Pressure Therapy.”. Br J Med Med Res. 2015;5:235.CrossRef
12.
Instrument WS, The WHO. STEPwise approach to chronic disease risk factor surveillance (STEPS). Geneva: World Health Organization; 2008.
13.
Committee IR. Guidelines for data processing and analysis of the International Physical Activity Questionnaire (IPAQ)—short and long forms. Retriev Sept. 2005;17:2008.
14.
Goldstein CM, Gathright EC, Dolansky MA, Gunstad J, Sterns A, Redle JD, Josephson R, Hughes JW. Randomized controlled feasibility trial of two telemedicine medication reminder systems for older adults with heart failure. J Telemed Telecare. 2014;20:293–9.CrossRefPubMed
15.
16.
Rich MW, Beckham V, Wittenberg C, Leven CL, Freedland KE, Carney RM. A multidisciplinary intervention to prevent the readmission of elderly patients with congestive heart failure. N Engl J Med. 1995;333:1190–5.CrossRefPubMed
17.
Glanz K, Rimer BK, Viswanath K. Health behavior and health education: theory, research, and practice: John Wiley & Sons; 2008.
18.
Green LW, Kreuter MW. Health program planning: an educational and ecological approach. 4th ed. New York: McGraw-Hill; 2005.
Metadata
Title
Comparing the effectiveness of the BPMAP (Blood Pressure Management Application) and usual care in self-management of primary hypertension and adherence to treatment in patients aged 30–60 years: study protocol for a randomized controlled trial
Authors
Mahnaz Ashoorkhani
Ali Bozorgi
Reza Majdzadeh
Hamed Hosseini
Ali Yoonessi
Ali Ramezankhani
Hassan Eftekhar
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Trials / Issue 1/2016
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-016-1638-0

Other articles of this Issue 1/2016

Trials 1/2016 Go to the issue

Study protocol

Pressure RElieving Support SUrfaces: a Randomised Evaluation 2 (PRESSURE 2): study protocol for a randomised controlled trial

Study protocol

Cognitive behavioral therapy program for cannabis use cessation in first-episode psychosis patients: study protocol for a randomized controlled trial

Study protocol

Multipoint Pacing versus conventional ICD in Patients with a Narrow QRS complex (MPP Narrow QRS trial): study protocol for a pilot randomized controlled trial

Review

Adaptive designs undertaken in clinical research: a review of registered clinical trials

Study protocol

The NSPCC UK Minding the Baby® (MTB) home-visiting programme, supporting young mothers (aged 14–25) in the first 2 years of their baby's life: study protocol for a randomised controlled trial

Erratum

Erratum to: ‘The advance care planning PREPARE study among older Veterans with serious and chronic illness: study protocol for a randomized controlled trial’