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Open Access 01-12-2015 | Letter

Reduced proliferation in breast cancer cells contacting the neighboring adipocytes in human breast cancer tissues

Authors: Han Suk Ryu, Han-Byoel Lee, Wonshik Han, Dong-Young Noh, Hyeong-Gon Moon

Published in: Breast Cancer Research | Issue 1/2015

Excerpt

The process of tumor formation and progression is a result of the complex interaction between malignant epithelial cells and the various cell populations in the tumor microenvironment [1, 2]. Recently, the role of cancer-associated adipocytes in cancer progression has been an active area of research, and many studies have suggested a proinvasive and prometastatic effect of the cancer-associated adipocytes [3, 4]. The cancer-promoting effect of adipocytes seems to originate from their ability to induce inflammatory milieu and to provide an energy source for cancer cells [5, 6]. …

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Title: Reduced proliferation in breast cancer cells contacting the neighboring adipocytes in human breast cancer tissues
Authors: Han Suk Ryu
Han-Byoel Lee
Wonshik Han
Dong-Young Noh
Hyeong-Gon Moon
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Breast Cancer Research / Issue 1/2015
Electronic ISSN: 1465-542X
DOI: https://doi.org/10.1186/s13058-015-0602-3

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