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Critical Care
Published in: Critical Care 1/2020

01-12-2020 | Acute Kidney Injury | Research Letter

Clearance of micronutrients during continuous renal replacement therapy

Authors: Nuttha Lumlertgul, Danielle E. Bear, Marlies Ostermann

Published in: Critical Care | Issue 1/2020

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Excerpt

Malnutrition is common in critically ill patients with acute kidney injury (AKI), especially if renal replacement therapy (RRT) is needed. There are several potential explanations, including nutrient losses during RRT. Although previous studies confirmed that micronutrients were detectable in effluent fluid [1‐4], daily losses have not been formally quantified. In addition, information about the transport characteristics of individual micronutrients during RRT is lacking. …
Literature
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Oh WC, Mafrici B, Rigby M, Harvey D, Sharman A, Allen JC, Mahajan R, Gardner DS, Devonald MAJ. Micronutrient and amino acid losses during renal replacement therapy for acute kidney injury. Kidney Int Rep. 2019;4(8):1094–108.CrossRef
2.
Story DA, Ronco C, Bellomo R. Trace element and vitamin concentrations and losses in critically ill patients treated with continuous venovenous hemofiltration. Crit Care Med. 1999;27(1):220–3.CrossRef
3.
Berger MM, Shenkin A, Revelly JP, Roberts E, Cayeux MC, Baines M, Chioléro RL. Copper, selenium, zinc, and thiamine balances during continuous venovenous hemodiafiltration in critically ill patients. Am J Clin Nutr. 2004;80(2):410–6.CrossRef
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Zappitelli M, Juarez M, Castillo L, Coss-Bu J, Goldstein SL. Continuous renal replacement therapy amino acid, trace metal and folate clearance in critically ill children. Intensive Care Med. 2009;35(4):698–706.CrossRef
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Ostermann M, Summers J, Lei K, Card D, Harrington DJ, Sherwood R, et al. Micronutrients in critically ill patients with severe acute kidney injury: a prospective study. Sci Rep. 2020;10(1):1505.CrossRef
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Ostermann M, Macedo E, Oudemans-van Straaten HM. How to feed a patient with acute kidney injury. Intensive Care Med. 2019;45(7):1006–8.CrossRef
Metadata
Title
Clearance of micronutrients during continuous renal replacement therapy
Authors
Nuttha Lumlertgul
Danielle E. Bear
Marlies Ostermann
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03347-x

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