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At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
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Critical Care
Literature
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Shimazui T, Nakada TA, Walley KR, Oshima T, Abe T, Ogura H, Shiraishi A, Kushimoto S, Saitoh D, Fujishima S, et al. Significance of body temperature in elderly patients with sepsis. Crit Care. 2020;24(1):387.CrossRef
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Schortgen F, Clabault K, Katsahian S, Devaquet J, Mercat A, Deye N, Dellamonica J, Bouadma L, Cook F, Beji O, et al. Fever control using external cooling in septic shock: a randomized controlled trial. Am J Respir Crit Care Med. 2012;185(10):1088–95.CrossRef
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Schortgen F, Charles-Nelson A, Bouadma L, Bizouard G, Brochard L, Katsahian S. Respective impact of lowering body temperature and heart rate on mortality in septic shock: mediation analysis of a randomized trial. Intensive Care Med. 2015;41(10):1800–8.CrossRef
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Rahmig J, Kuhn M, Neugebauer H, Juttler E, Reichmann H, Schneider H. Normothermia after decompressive surgery for space-occupying middle cerebral artery infarction: a protocol-based approach. BMC Neurol. 2017;17(1):205.CrossRef
Metadata
Title
Hyperthermia is a predictor of high mortality in patients with sepsis
Authors
Yanfei Shen
Yangfang Lou
Shiping Zhu
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03263-0

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