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Critical Care

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01-12-2020 | Septicemia | Letter

High-dose intravenous vitamin C may help in cytokine storm in severe SARS-CoV-2 infection

Authors: Adriana Françozo de Melo, Mauricio Homem-de-Mello

Published in: Critical Care | Issue 1/2020

Excerpt

To the editor: …

Carr AC, Rosengrave PC, Bayer S, Chambers S, Mehrtens J, Shaw GM. Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes. Crit Care. 2017;21:300. https://doi.org/10.1186/s13054-017-1891-y.CrossRefPubMedPubMedCentral

Du W-D, Yuan Z-R, Sun J, Tang J-X, Cheng A-Q, Shen D-M, et al. Therapeutic efficacy of high-dose vitamin C on acute pancreatitis and its potential mechanisms. World J Gastroenterol. 2003;9:2565–9 Available from: https://pubmed.ncbi.nlm.nih.gov/14606098.CrossRef

The RECOVERY Collaborative Group. Dexamethasone in hospitalized patients with Covid-19 — preliminary report. N Engl J Med. 2020:1–11. https://doi.org/10.1056/NEJMoa2021436.

Carr AC. A new clinical trial to test high-dose vitamin C in patients with COVID-19. Crit Care. 2020;24:133. https://doi.org/10.1186/s13054-020-02851-4.CrossRefPubMedPubMedCentral

Hernández A, Papadakos PJ, Torres A, González DA, Vives M, Ferrando C, et al. Two known therapies could be useful as adjuvant therapy in critical patients infected by COVID-19 TT - Dos terapias conocidas podrían ser efectivas como adyuvantes en el paciente crítico infectado por COVID-19. Rev Esp Anestesiol Reanim. 2020;67:245–52 Available from: https://pubmed.ncbi.nlm.nih.gov/32303365.CrossRef

Title: High-dose intravenous vitamin C may help in cytokine storm in severe SARS-CoV-2 infection
Authors: Adriana Françozo de Melo
Mauricio Homem-de-Mello
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Septicemia
Septicemia
Acute Pancreatitis
SARS-CoV-2
Cytokines
Published in: Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-020-03228-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

High-dose intravenous vitamin C may help in cytokine storm in severe SARS-CoV-2 infection

Excerpt

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Excerpt

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