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Critical Care
Published in: Critical Care 1/2020

Open Access 01-12-2020 | Phlebothrombosis | Research Letter

Low molecular weight heparins in COVID-19 patients: beware of augmented renal clearance!

Authors: Teresa Maria Tomasa-Irriguible, Sergi Martínez-Vega, Ester Mor-Marco, Alba Herraiz-Ruiz, Laura Raguer-Pardo, Carlos Cubells-Larrosa

Published in: Critical Care | Issue 1/2020

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Excerpt

Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019 pandemic (COVID-19). Histologic analysis of pulmonary vessels in patients with COVID-19 has shown widespread thrombosis with alveolar capillary microthrombi [1]. COVID-19 is known to be associated with thrombotic phenomena that are related to the high mortality of this disease and proper treatment can improve the survival of these patients [2‐5]. …
Literature
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Paranjpe I, Fuster V, Lala A, Russak A, Glicksberg BS, Levin MA, Charney AW, Narula J, Fayad ZA, Bagiella E, Zhao S, Nadkarni GN. Association of treatment dose anticoagulation with in-hospital survival among hospitalized patients with COVID-19. J Am Coll Cardiol. 2020. https://​doi.​org/​10.​1016/​j.​jacc.​2020.​05.​001.
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Lillicrap D. Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia. J Thromb Haemost. 2020;18(4):786-7.
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Yin S, Huang M, Li D, Tang N. Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2. J Thromb Thrombolysis. 2020;18(4):786-7.
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Tang N, Bai H, Chen X, Gong J, Li D, Sun Z. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020;18(4):786-7.
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Metadata
Title
Low molecular weight heparins in COVID-19 patients: beware of augmented renal clearance!
Authors
Teresa Maria Tomasa-Irriguible
Sergi Martínez-Vega
Ester Mor-Marco
Alba Herraiz-Ruiz
Laura Raguer-Pardo
Carlos Cubells-Larrosa
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03058-3

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