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Open Access 01-12-2020 | SARS-CoV-2 | Research Letter

The association of low serum albumin level with severe COVID-19: a systematic review and meta-analysis

Authors: Muhammad Aziz, Rawish Fatima, Wade Lee-Smith, Ragheb Assaly

Published in: Critical Care | Issue 1/2020

Excerpt

The coronavirus disease 2019 (COVID-19) pandemic necessitates identifying laboratory markers to assist the clinicians in early recognition of severe disease [1]. Given the unclear association of hypoalbuminemia and severe COVID-19, we conducted a systematic review and meta-analysis to answer this. …

Aziz M, Fatima R, Assaly R. Elevated interleukin-6 and severe COVID-19: a meta-analysis. J Med Virol. 2020. https://doi.org/10.1002/jmv.25948.

Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. https://doi.org/10.1016/S0140-6736(20)30183-5.CrossRef

Chen T, Wu D, Chen H, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ. 2020;368:m1091. https://doi.org/10.1136/bmj.m1091.

Liu Y, Yang Y, Zhang C, et al. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Sci China Life Sci. 2020;63:364–74. https://doi.org/10.1007/s11427-020-1643-8.CrossRef

Chen G, Wu D, Guo W, et al. Clinical and immunological features of severe and moderate coronavirus disease 2019. J Clin Invest. 2020;130:2620–9. https://doi.org/10.1172/JCI137244.CrossRef

Mo P, Xing Y, Xiao Y, et al. Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China. Clin Infect Dis. 2020;ciaa270. https://doi.org/10.1093/cid/ciaa270.

Wan S, Xiang Y, Fang W, et al. Clinical features and treatment of COVID-19 patients in northeast Chongqing. J Med Virol. 2020;10.1002/jmv.25783. .

Liu C, Jiang ZC, Shao CX, et al. Zhonghua Gan Zang Bing Za Zhi. 2020;28:107–11. https://doi.org/10.3760/cma.j.issn.1007-3418.2020.02.003.

Liu M, He P, Liu HG, et al. Zhonghua Jie He He Hu Xi Za Zhi. 2020;43:E016. https://doi.org/10.3760/cma.j.issn.1001-0939.2020.0016.

10.

Liu W, Tao ZW, Wang L, et al. Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease. Chin Med J (Engl). 2020;133:1032–8. https://doi.org/10.1097/CM9.0000000000000775.CrossRef

11.

Zhang Y, Zheng L, Liu L, Zhao M, Xiao J, Zhao Q. Liver impairment in COVID-19 patients: A retrospective analysis of 115 cases from a single centre in Wuhan city, China. Liver Int. 2020;10.1111/liv.14455. https://doi.org/10.1111/liv.14455.

12.

Zhou Y, Zhang Z, Tian J, Xiong S. Risk factors associated with disease progression in a cohort of patients infected with the 2019 novel coronavirus. Ann Palliat Med. 2020;9:428–36. https://doi.org/10.21037/apm.2020.03.26.CrossRef

13.

Akirov A, Masri-Iraqi H, Atamna A, Shimon I. Low Albumin Levels Are Associated with Mortality Risk in Hospitalized Patients. Am J Med. 2017;130:1465.e11–65.e19. https://doi.org/10.1016/j.amjmed.2017.07.020.CrossRef

14.

Soeters PB, Wolfe RR, Shenkin A. Hypoalbuminemia: Pathogenesis and Clinical Significance. JPEN J Parenter Enteral Nutr. 2019;43:181–93. https://doi.org/10.1002/jpen.1451.CrossRef

Title: The association of low serum albumin level with severe COVID-19: a systematic review and meta-analysis
Authors: Muhammad Aziz
Rawish Fatima
Wade Lee-Smith
Ragheb Assaly
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: SARS-CoV-2
COVID-19
Published in: Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-020-02995-3

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The association of low serum albumin level with severe COVID-19: a systematic review and meta-analysis

Excerpt

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Excerpt

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