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Critical Care
Published in: Critical Care 1/2020

Open Access 01-12-2020 | Expectoration | Research Letter

SARS-CoV-2 viral load in sputum correlates with risk of COVID-19 progression

Authors: Xia Yu, Shanshan Sun, Yu Shi, Hao Wang, Ruihong Zhao, Jifang Sheng

Published in: Critical Care | Issue 1/2020

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Excerpt

The pandemic of coronavirus diseases 2019 (COVID-19) imposes a heavy burden on medical resources [1]. Whether there is correlation between viral load and disease severity has not been clarified. In the study, we retrospectively collected the virological data, as well as demographic, epidemiological clinical information of 92 patients with confirmed COVID-19 in a single hospital in Zhejiang Province, China. We compared the baseline viral loads between severe patients and those mild to moderate at admission and also between those developing severe disease during hospitalization and those not. …
Literature
1.
Ji Y, Ma Z, Peppelenbosch MP, Pan Q. Potential association between COVID-19 mortality and health-care resource availability. Lancet Glob Health. 2020;8(4):e480.CrossRef
2.
Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, Yu J, Kang M, Song Y, Xia J, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med. 2020;382(12):1177–9.CrossRef
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Pan Y, Zhang D, Yang P, Poon LLM, Wang Q. Viral load of SARS-CoV-2 in clinical samples. Lancet Infect Dis. 2020;20(4):411–2.CrossRef
Metadata
Title
SARS-CoV-2 viral load in sputum correlates with risk of COVID-19 progression
Authors
Xia Yu
Shanshan Sun
Yu Shi
Hao Wang
Ruihong Zhao
Jifang Sheng
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-02893-8

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