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Critical Care
Published in: Critical Care 1/2018

Open Access 01-12-2018 | Letter

Specific dynamic of serum procalcitonin in critically ill patients affected by Gram-negative bacilli septic thrombophlebitis

Authors: Martina Spaziante, Giancarlo Ceccarelli, Samir Al Moghazi, Francesco Alessandri, Mario Venditti

Published in: Critical Care | Issue 1/2018

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Excerpt

We read with interest the study by Thomas-Rüddel et al. [1] evaluating the influence of specific pathogens and different foci of infections on serum procalcitonin (PCT) concentrations. The authors concluded that PCT levels were higher in patients with Gram-negative bacteremia compared with patients with Gram-positive or fungal diseases, whereas urogenital and abdominal foci of infection were associated with twofold increased PCT values, independent of causative pathogen. Unfortunately, this study did not provide data on PCT trends in patients affected by endovascular infections. …
Literature
1.
Thomas-Rüddel DO, Poidinger B, Kott M, Weiss M, Reinhart K, Bloos F, MEDUSA study group. Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia. Crit Care. 2018;22(1):128.CrossRefPubMedPubMedCentral
2.
Yan ST, Sun LC, Jia HB, Gao W, Yang JP, Zhang GQ. Procalcitonin levels in bloodstream infections caused by different sources and species of bacteria. Am J Emerg Med. 2017;35(4):579–83.CrossRefPubMed
3.
Ayres JS, Schneider DS. Two ways to survive an infection: what resistance and tolerance can teach us about treatments for infectious diseases. Nat Rev Immunol. 2008;8(11):889–95.CrossRefPubMedPubMedCentral
4.
Ceccarelli G, Giuliano S, Falcone M, Venditti M. Follow-up blood cultures: a 2.0 diagnostic tool in patients with Gram-negative bacteremia and septic thrombophlebitis. Clin Infect Dis. 2018;66(7):1154–5.CrossRefPubMed
Metadata
Title
Specific dynamic of serum procalcitonin in critically ill patients affected by Gram-negative bacilli septic thrombophlebitis
Authors
Martina Spaziante
Giancarlo Ceccarelli
Samir Al Moghazi
Francesco Alessandri
Mario Venditti
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2018
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-018-2116-8

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