Published in:
Open Access
01-12-2017 | Letter
The term “supplemental parenteral nutrition” should be restricted to studies meeting specific technical criteria
Authors:
Claude Pichard, Mette M. Berger
Published in:
Critical Care
|
Issue 1/2017
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Excerpt
Wischmeyer et al. recently reported the promising results of their TOP-UP pilot trial [
1]. This letter aims at clarifying a semantic problem which has complicated the interpretation of many studies. The authors’ hypothesis was that supplemental parenteral nutrition (SPN) combined with enteral nutrition (EN) in ICU patients would improve 60-day survival: 125 patients on mechanical ventilation for acute respiratory failure were enrolled “within 3 days”. Patients were on EN or EN + SPN to reach 100% of the prescribed energy target, which was 25 or 20 kcal/kg actual body weight (BW) for BMI < 25 or > 35, respectively. …