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Open Access 01-12-2017 | Editorial

Traversing the valley of glycemic control despair

Authors: J. Geoffrey Chase, Jennifer L. Dickson

Published in: Critical Care | Issue 1/2017

Excerpt

The debate on glycemic control (GC) in critical care nears the 16-year mark since the initial landmark study. In this journal, Mesotten et al. [1], from the Leuven group of the original study, present the results of the LOGIC-2 multicenter trial of model-based GC versus standard nurse GC. …

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Kelley D, Conner DR. The emotional cycle of change. In: Jones JE, Pfeiffer JW, editors. The 1979 annual handbook for group facilitators. San Diego: University Associates; 1979. p. 117–22.

Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345(19):1359–67.CrossRefPubMed

Finfer S, Chittock DR, Su SY, Blair D, Foster D, Dhingra V, Bellomo R, Cook D, Dodek P, Henderson WR, Hebert PC, Heritier S, Heyland DK, McArthur C, McDonald E, Mitchell I, Myburgh JA, Norton R, Potter J, Robinson BG, Ronco JJ. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009;360(13):1283–97.CrossRefPubMed

Preiser JC, Devos P, Ruiz-Santana S, Melot C, Annane D, Groeneveld J, Iapichino G, Leverve X, Nitenberg G, Singer P, Wernerman J, Joannidis M, Stecher A, Chiolero R. A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study. Intensive Care Med. 2009;35(10):1738–48.CrossRefPubMed

Kalfon P, Giraudeau B, Ichai C, Guerrini A, Brechot N, Cinotti R, Dequin PF, Riu-Poulenc B, Montravers P, Annane D, Dupont H, Sorine M, Riou B, Group C-RS. Tight computerized versus conventional glucose control in the ICU: a randomized controlled trial. Intensive Care Med. 2014;40(2):171–81.CrossRefPubMed

Preiser JC, Straaten HM. Glycemic control: please agree to disagree. Intensive Care Med. 2016;42(9):1482–4.CrossRefPubMed

Marik PE. Tight glycemic control in acutely ill patients: low evidence of benefit, high evidence of harm! Intensive Care Med. 2016;42(9):1475–7.CrossRefPubMed

Krinsley JS, Preiser JC. Time in blood glucose range 70 to 140 mg/dl >80% is strongly associated with increased survival in non-diabetic critically ill adults. Crit Care. 2015;19:179.CrossRefPubMedPubMedCentral

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Uyttendaele V, Dickson JL, Shaw GM, Desaive T, Chase JG. Untangling glycaemia and mortality in critical care. Crit Care. 2017;21(1):152.CrossRefPubMedPubMedCentral

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Chase JG, Pretty CG, Pfeifer L, Shaw GM, Preiser JC, Le Compte AJ, Lin J, Hewett D, Moorhead KT, Desaive T. Organ failure and tight glycemic control in the SPRINT study. Crit Care. 2010;14(4):R154.CrossRefPubMedPubMedCentral

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Chase JG, Le Compte AJ, Preiser JC, Shaw GM, Penning S, Desaive T. Physiological modeling, tight glycemic control, and the ICU clinician: what are models and how can they affect practice? Ann Intensive Care. 2011;1(1):11.CrossRefPubMedPubMedCentral

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Dickson JL, Gunn C, Chase JG. Humans are horribly variable. Int J Clin Med Imaging. 2014;1(2):1–1000142.

14.

Pretty CG, Le Compte AJ, Chase JG, Shaw GM, Preiser JC, Penning S, Desaive T. Variability of insulin sensitivity during the first 4 days of critical illness: implications for tight glycemic control. Ann Intensive Care. 2012;2(1):17.CrossRefPubMedPubMedCentral

15.

Stewart KW, Pretty CG, Tomlinson H, Thomas FL, Homlok J, Noemi SN, Illyes A, Shaw GM, Benyo B, Chase JG. Safety, efficacy and clinical generalization of the STAR protocol: a retrospective analysis. Ann Intensive Care. 2016;6(1):24.CrossRefPubMedPubMedCentral

Title: Traversing the valley of glycemic control despair
Authors: J. Geoffrey Chase
Jennifer L. Dickson
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Critical Care / Issue 1/2017
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-017-1824-9

At a glance: The ONWARDS insulin icodec trials

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Traversing the valley of glycemic control despair

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At a glance: The ONWARDS insulin icodec trials

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