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Critical Care
Published in: Critical Care 1/2016

Open Access 01-12-2016 | Letter

Concerns about LUNG-SAFE: response to the letter to the Editor of Critical Care by Bellani et al.

Authors: Jesús Villar, Robert M. Kacmarek

Published in: Critical Care | Issue 1/2016

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Excerpt

We appreciate the opportunity to respond to the letter by Bellani et al. regarding our commentary on LUNG-SAFE. They expressed concern regarding the four potential biases we raised about their study. …
Literature
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Caser EB, Zandonade E, Pereira E, et al. Impact of distinct definitions of acute lung injury on its incidence and outcomes in Brazilian ICUs: prospective evaluation of 7,133 patients. Crit Care Med. 2014;42:574–82.CrossRefPubMed
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Villar J, Pérez-Méndez L, López J, et al. An early PEEP/FIO2 trial identifies different degrees of lung injury in patients with different degrees of lung injury. Am J Respir Crit Care Med. 2007;176:795–804.CrossRefPubMed
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Villar J, Perez-Mendez L, Blanco J, et al. A universal definition of ARDS: the PaO2/FIO2 ratio under standard ventilator settings—a prospective multicenter validation study. Intensive Care Med. 2013;39:583–92.CrossRefPubMed
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Tomashefski Jr JF. Pulmonary pathology of acute respiratory distress syndrome. Clin Chest Med. 2000;21:435–66.CrossRefPubMed
Metadata
Title
Concerns about LUNG-SAFE: response to the letter to the Editor of Critical Care by Bellani et al.
Authors
Jesús Villar
Robert M. Kacmarek
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2016
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-016-1477-0

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