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Published in: Critical Care 6/2014

Open Access 01-12-2014 | Letter

Search for biomarkers in critically ill patients: a new approach based on nuclear magnetic resonance spectroscopy of mini-bronchoalveolar lavage fluid

Authors: Chandan Singh, Ratan Kumar Rai, Afzal Azim, Neeraj Sinha, Arvind Kumar Baronia

Published in: Critical Care | Issue 6/2014

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Abstract

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Appendix
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Literature
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go back to reference Beckonert O, Keun HC, Ebbels TMD, Bundy J, Holmes E, Lindon JC, Nicholson JK: Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat Protoc. 2007, 2: 2692-2703. 10.1038/nprot.2007.376.CrossRef Beckonert O, Keun HC, Ebbels TMD, Bundy J, Holmes E, Lindon JC, Nicholson JK: Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat Protoc. 2007, 2: 2692-2703. 10.1038/nprot.2007.376.CrossRef
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go back to reference Rai RK, Azim A, Sinha N, Sahoo J, Singh C, Ahmed A, Saigal S, Baronia A, Gupta D, Gurjar M, Poddar B, Singh RK: Metabolic profiling in human lung injuries by high-resolution nuclear magnetic resonance spectroscopy of bronchoalveolar lavage fluid (BALF). Metabolomics. 2013, 9: 667-676. 10.1007/s11306-012-0472-y.CrossRef Rai RK, Azim A, Sinha N, Sahoo J, Singh C, Ahmed A, Saigal S, Baronia A, Gupta D, Gurjar M, Poddar B, Singh RK: Metabolic profiling in human lung injuries by high-resolution nuclear magnetic resonance spectroscopy of bronchoalveolar lavage fluid (BALF). Metabolomics. 2013, 9: 667-676. 10.1007/s11306-012-0472-y.CrossRef
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go back to reference Singh C, Rai R, Azim A, Sinha N, Ahmed A, Singh K, Kayastha A, Baronia AK, Gurjar M, Poddar B, Singh R: Metabolic profiling of human lung injury by 1H high-resolution nuclear magnetic resonance spectroscopy of blood serum.Metabolomics 2014. [Epub ahead of print]., Singh C, Rai R, Azim A, Sinha N, Ahmed A, Singh K, Kayastha A, Baronia AK, Gurjar M, Poddar B, Singh R: Metabolic profiling of human lung injury by 1H high-resolution nuclear magnetic resonance spectroscopy of blood serum.Metabolomics 2014. [Epub ahead of print].,
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go back to reference Singh C, Rai R, Azim A, Sinha N, Baronia A: Mini-bronchoalveolar lavage fluid can be used for biomarker identification in patients with lung injury by employing 1H NMR spectroscopy. Crit Care. 2013, 17: 430-10.1186/cc12607.CrossRef Singh C, Rai R, Azim A, Sinha N, Baronia A: Mini-bronchoalveolar lavage fluid can be used for biomarker identification in patients with lung injury by employing 1H NMR spectroscopy. Crit Care. 2013, 17: 430-10.1186/cc12607.CrossRef
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go back to reference Khilnani GC, Arafath KT, Hadda V, Kapil A, Sood S, Sharma SK: Comparison of bronchoscopic and non-bronchoscopic techniques for diagnosis of ventilator associated pneumonia. Indian J Crit Care Med. 2011, 15: 16-23. 10.4103/0972-5229.78218.CrossRef Khilnani GC, Arafath KT, Hadda V, Kapil A, Sood S, Sharma SK: Comparison of bronchoscopic and non-bronchoscopic techniques for diagnosis of ventilator associated pneumonia. Indian J Crit Care Med. 2011, 15: 16-23. 10.4103/0972-5229.78218.CrossRef
Metadata
Title
Search for biomarkers in critically ill patients: a new approach based on nuclear magnetic resonance spectroscopy of mini-bronchoalveolar lavage fluid
Authors
Chandan Singh
Ratan Kumar Rai
Afzal Azim
Neeraj Sinha
Arvind Kumar Baronia
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Critical Care / Issue 6/2014
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-014-0594-x

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