Skip to main content
Top
Published in: Italian Journal of Pediatrics 1/2018

Open Access 01-12-2018 | Case report

Salmonella osteomyelitis in a previously healthy neonate: a case report and review of the literature

Authors: Canyang Zhan, Jing Du, Lihua Chen

Published in: Italian Journal of Pediatrics | Issue 1/2018

Login to get access

Abstract

Background

Acute osteomyelitis, which is uncommon in neonates, needs to be quickly diagnosed and treated to avoid devastating sequelae. Therefore, it is important to maintain a high index of suspicion and be aware of the evolving epidemiology and of the emergence of antibiotic resistant and aggressive strains requiring careful monitoring and targeted therapy. The most frequently isolated bacterium in neonates with osteomyelitis is Staphylococcus aureus, while Salmonella is an unusual organism causing osteomyelitis and is exceedingly rare in non-sickle cell disease children.

Case presentation

We report an extremely rare case of neonatal osteomyelitis caused by Salmonella in a neonate, who was previously healthy. We report this case because it was caused by a rare pathogenic germ in newborns and by its non-specific presentation.

Conclusions

Salmonella should be kept in mind in the differential diagnosis of neonatal osteomyelitis. It is important to start antibiotic therapy as soon as possible and to adjust therapy in relation to the susceptibility of the bacterial strain.
Literature
1.
go back to reference Dodwell ER. Osteomyelitis and septic arthritis in children: current concepts. Curr Opin Pediatr. 2013;25:58–63.CrossRefPubMed Dodwell ER. Osteomyelitis and septic arthritis in children: current concepts. Curr Opin Pediatr. 2013;25:58–63.CrossRefPubMed
2.
go back to reference Bula-Rudas FJ, Rathore MH, Maraqa NF. Salmonella infections in childhood. Adv Pediatr Infect Dis. 2015;62:29–58. Bula-Rudas FJ, Rathore MH, Maraqa NF. Salmonella infections in childhood. Adv Pediatr Infect Dis. 2015;62:29–58.
3.
go back to reference Jones TF, Ingram LA, Fullerton KE, Marcus R, Anderson BJ, McCarthy PV, et al. A case-control study of the epidemiology of sporadic salmonella infection in infants. Pediatrics. 2006;118:2380–7.CrossRefPubMed Jones TF, Ingram LA, Fullerton KE, Marcus R, Anderson BJ, McCarthy PV, et al. A case-control study of the epidemiology of sporadic salmonella infection in infants. Pediatrics. 2006;118:2380–7.CrossRefPubMed
4.
go back to reference Spencer J, Cattermole G, Andrade T, Dryden M, Fowler J. Salmonella osteoarticular infection without predisposing factors. J R Soc Med. 1999;92:363–4.CrossRefPubMedPubMedCentral Spencer J, Cattermole G, Andrade T, Dryden M, Fowler J. Salmonella osteoarticular infection without predisposing factors. J R Soc Med. 1999;92:363–4.CrossRefPubMedPubMedCentral
5.
go back to reference Tsagris V, Vliora C, Mihelarakis I, Syridou G, Pasparakis D, Lebessi E, et al. Salmonella osteomyelitis in previously healthy children: report of 4 cases and review of the literature. Pediatr Infect Dis J. 2016;35:116–7.PubMed Tsagris V, Vliora C, Mihelarakis I, Syridou G, Pasparakis D, Lebessi E, et al. Salmonella osteomyelitis in previously healthy children: report of 4 cases and review of the literature. Pediatr Infect Dis J. 2016;35:116–7.PubMed
6.
go back to reference Kothari NA, Pelchovitz DJ, Meyer JS. Imaging of musculoskeletal infections. Radiol Clin N Am. 2001;39:653–71.CrossRefPubMed Kothari NA, Pelchovitz DJ, Meyer JS. Imaging of musculoskeletal infections. Radiol Clin N Am. 2001;39:653–71.CrossRefPubMed
7.
go back to reference Blickman JG, van Die CE, de Rooy JW. Current imaging concepts in pediatric osteomyelitis. Eur Radiol. 2004;14:L55–64.CrossRefPubMed Blickman JG, van Die CE, de Rooy JW. Current imaging concepts in pediatric osteomyelitis. Eur Radiol. 2004;14:L55–64.CrossRefPubMed
8.
go back to reference Saturveithan C, Arieff A, Premganesh G, Sivapathasundaram N. Salmonella osteomyelitis in a one year old child without sickle cell disease: a case report. Malays Orthop J. 2014;8:52–4.CrossRefPubMedPubMedCentral Saturveithan C, Arieff A, Premganesh G, Sivapathasundaram N. Salmonella osteomyelitis in a one year old child without sickle cell disease: a case report. Malays Orthop J. 2014;8:52–4.CrossRefPubMedPubMedCentral
9.
go back to reference Tonogai I, Hamada Y, Hibino N, Sato R, Henmi T, Sairyo K. Salmonella osteomyelitis of the distal radius in a healthy young adult patient: report of a rare case and literature review. J Med Investig. 2015;62:97–9.CrossRef Tonogai I, Hamada Y, Hibino N, Sato R, Henmi T, Sairyo K. Salmonella osteomyelitis of the distal radius in a healthy young adult patient: report of a rare case and literature review. J Med Investig. 2015;62:97–9.CrossRef
Metadata
Title
Salmonella osteomyelitis in a previously healthy neonate: a case report and review of the literature
Authors
Canyang Zhan
Jing Du
Lihua Chen
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue 1/2018
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/s13052-018-0464-2

Other articles of this Issue 1/2018

Italian Journal of Pediatrics 1/2018 Go to the issue