Skip to main content
Top
Published in: Italian Journal of Pediatrics 1/2016

Open Access 01-12-2016 | Research

Cardiorespiratory fitness and sports activities in children and adolescents with solitary functioning kidney

Authors: Giancarlo Tancredi, Caterina Lambiase, Alessandra Favoriti, Francesca Ricupito, Sara Paoli, Marzia Duse, Giovanna De Castro, Anna Maria Zicari, Giovanna Vitaliti, Raffaele Falsaperla, Riccardo Lubrano

Published in: Italian Journal of Pediatrics | Issue 1/2016

Login to get access

Abstract

Background

An increasing number of children with chronic disease require a complete medical examination to be able to practice physical activity. Particularly children with solitary functioning kidney (SFK) need an accurate functional evaluation to perform sports activities safely. The aim of our study was to evaluate the influence of regular physical activity on the cardiorespiratory function of children with solitary functioning kidney.

Method

Twenty-nine patients with congenital SFK, mean age 13.9 ± 5.0 years, and 36 controls (C), mean age 13.8 ± 3.7 years, underwent a cardiorespiratory assessment with spirometry and maximal cardiopulmonary exercise testing. All subjects were divided in two groups: sedentary (S) and trained (T) patients, by means of a standardized questionnaire about their weekly physical activity.

Results

We found that mean values of maximal oxygen consumption (VO2max) and exercise time (ET) were higher in T subjects than in S subjects. Particularly SFK-T presented mean values of VO2max similar to C-T and significantly higher than C-S (SFK-T: 44.7 ± 6.3 vs C-S: 37.8 ± 3.7 ml/min/kg; p < 0.0008). We also found significantly higher mean values of ET (minutes) in minutes in SFK-T than C-S subjects (SFK-T: 12.9 ± 1.6 vs C-S: 10.8 ± 2.5 min; p <0.02).

Conclusion

Our study showed that regular moderate/high level of physical activity improve aerobic capacity (VO2max) and exercise tolerance in congenital SFK patients without increasing the risks for cardiovascular accidents and accordingly sports activities should be strongly encouraged in SFK patients to maximize health benefits.
Literature
1.
go back to reference Westland R, Schreuder MF, van Goudoever JB, Sanna-Cherchi S, van Wijk JA. Clinical implications of the solitary functioning kidney. Clin J Am SocNephrol. 2014;9:978–86.CrossRef Westland R, Schreuder MF, van Goudoever JB, Sanna-Cherchi S, van Wijk JA. Clinical implications of the solitary functioning kidney. Clin J Am SocNephrol. 2014;9:978–86.CrossRef
2.
go back to reference Kolvek G, Podracka L, Rosenberger J, Stewart RE, van Dijk JP, Reijneveld SA. Solitary functioning kidney in children: a follow-up study. Kidney Blood Press Res. 2014;39:272–8.PubMed Kolvek G, Podracka L, Rosenberger J, Stewart RE, van Dijk JP, Reijneveld SA. Solitary functioning kidney in children: a follow-up study. Kidney Blood Press Res. 2014;39:272–8.PubMed
3.
go back to reference Daradka I. Indication for nephrectomy in children: A report on 119 cases. Saudi J Kidney Dis Transpl. 2012;23:1221–6.PubMed Daradka I. Indication for nephrectomy in children: A report on 119 cases. Saudi J Kidney Dis Transpl. 2012;23:1221–6.PubMed
4.
go back to reference Dursun H, Bayazit AK, Büyükçelik M, Soran M, Noyan A, Anarat A. Associated anomalies in children with congenital solitary functioning kidney. Pediatr Surg Int. 2005;21:456–9.CrossRefPubMed Dursun H, Bayazit AK, Büyükçelik M, Soran M, Noyan A, Anarat A. Associated anomalies in children with congenital solitary functioning kidney. Pediatr Surg Int. 2005;21:456–9.CrossRefPubMed
5.
go back to reference Brenner BM, Meyer TW, Hostetter TH. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med. 1982;307:652–9.CrossRefPubMed Brenner BM, Meyer TW, Hostetter TH. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med. 1982;307:652–9.CrossRefPubMed
6.
go back to reference Westland R, Schreuder MF, Ket JC, van Wijk JA. Unilateral renal agenesis: a systematic review on associated anomalies and renal injury. Nephrol Dial Transplant. 2013;28:1844–55.CrossRefPubMed Westland R, Schreuder MF, Ket JC, van Wijk JA. Unilateral renal agenesis: a systematic review on associated anomalies and renal injury. Nephrol Dial Transplant. 2013;28:1844–55.CrossRefPubMed
7.
go back to reference Seeman T, Patzer L, John U, Dusek J, Vondrák K, Janda J, Misselwitz J. Blood pressure, renal function, and proteinuria in children with unilateral renal agenesis (URA). Kidney Blood Press Res. 2006;29:210–5.CrossRefPubMed Seeman T, Patzer L, John U, Dusek J, Vondrák K, Janda J, Misselwitz J. Blood pressure, renal function, and proteinuria in children with unilateral renal agenesis (URA). Kidney Blood Press Res. 2006;29:210–5.CrossRefPubMed
8.
go back to reference Nathan N, Wolfenden L, Williams CM. Educational interventions are effective in treating childhood obesity. Br J Sports Med. 2016;50:130–1.CrossRefPubMed Nathan N, Wolfenden L, Williams CM. Educational interventions are effective in treating childhood obesity. Br J Sports Med. 2016;50:130–1.CrossRefPubMed
9.
go back to reference Lubrano R, Tancredi G, BellelliE GI, Scateni S, Masciangelo R, De Castro G, Versacci P, Marco E. Influence of physical activity on cardiorespiratory fitness in children after renal transplantation. Nephrol Dial Transplant. 2012;27:1677–81.CrossRefPubMed Lubrano R, Tancredi G, BellelliE GI, Scateni S, Masciangelo R, De Castro G, Versacci P, Marco E. Influence of physical activity on cardiorespiratory fitness in children after renal transplantation. Nephrol Dial Transplant. 2012;27:1677–81.CrossRefPubMed
10.
go back to reference Weaver Jr DJ, Kimball TR, Knilans T, Mays W, Knecht SK, Gerdes YM, Witt S, Glascock BJ, Kartal J, Khoury P, Mitsnefes MM. Decreased maximal aerobic capacity in pediatric chronic kidney disease. J Am Soc Nephrol. 2008;19:624–30.CrossRefPubMedPubMedCentral Weaver Jr DJ, Kimball TR, Knilans T, Mays W, Knecht SK, Gerdes YM, Witt S, Glascock BJ, Kartal J, Khoury P, Mitsnefes MM. Decreased maximal aerobic capacity in pediatric chronic kidney disease. J Am Soc Nephrol. 2008;19:624–30.CrossRefPubMedPubMedCentral
11.
go back to reference Urbina E, Alpert B, Flynn J, Hayman L, Harshfield GA, Jacobson M, Mahoney L, McCrindle B, Mietus-Snyder M, Steinberger J, Daniels S. American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee. Ambulatory blood pressure monitoring in children and adolescent: recommendation for standard assessment: a scientific statement from the American Heart Association Atherosclerosis, hypertension and obesity in youth committee of the council on cardiovascular disease in the young and the council for high blood pressure research. Hypertension. 2008;52:433–51.CrossRefPubMed Urbina E, Alpert B, Flynn J, Hayman L, Harshfield GA, Jacobson M, Mahoney L, McCrindle B, Mietus-Snyder M, Steinberger J, Daniels S. American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee. Ambulatory blood pressure monitoring in children and adolescent: recommendation for standard assessment: a scientific statement from the American Heart Association Atherosclerosis, hypertension and obesity in youth committee of the council on cardiovascular disease in the young and the council for high blood pressure research. Hypertension. 2008;52:433–51.CrossRefPubMed
12.
go back to reference Flynn JT, Daniels SR, Hayman LL, Maahs DM, McCrindle BW, Mitsnefes M, Zachariah JP, Urbina EM. American Heart Association Atherosclerosis, Hypertension and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young. American Heart Association Atherosclerosis, Hypertension and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young. Update: ambulatory blood pressure monitoring in children and adolescents: a scientific statement from the American Heart Association. Hypertension. 2014;63:1116–35.CrossRefPubMedPubMedCentral Flynn JT, Daniels SR, Hayman LL, Maahs DM, McCrindle BW, Mitsnefes M, Zachariah JP, Urbina EM. American Heart Association Atherosclerosis, Hypertension and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young. American Heart Association Atherosclerosis, Hypertension and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young. Update: ambulatory blood pressure monitoring in children and adolescents: a scientific statement from the American Heart Association. Hypertension. 2014;63:1116–35.CrossRefPubMedPubMedCentral
13.
go back to reference American Thoracic Society. American College of Chest Physicians. ATS/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med. 2003;167:211–77.CrossRef American Thoracic Society. American College of Chest Physicians. ATS/ACCP statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med. 2003;167:211–77.CrossRef
14.
go back to reference Crocker PR, Bailey DA, Faulkner RA. Measuring general levels of physical activity: preliminary evidence for the physical activity questionnaire for older children. Med Sci Sports Exerc. 1997;29:1344–9.CrossRefPubMed Crocker PR, Bailey DA, Faulkner RA. Measuring general levels of physical activity: preliminary evidence for the physical activity questionnaire for older children. Med Sci Sports Exerc. 1997;29:1344–9.CrossRefPubMed
15.
go back to reference American Thoracic Society/European Respiratory Society Task Force. Standardisation of Lung Function Testing. Standardisation of spirometry. Eur Respir J. 2005;26:319–38.CrossRef American Thoracic Society/European Respiratory Society Task Force. Standardisation of Lung Function Testing. Standardisation of spirometry. Eur Respir J. 2005;26:319–38.CrossRef
16.
go back to reference Tancredi G, Versacci P, Pasquino AM, Vittucci AC, Pucarelli I, Cappa M, Di Mambro C, Marino B. Cardiopulmonary response to exercise and cardiac assessment in patients with Turner syndrome. Am J Cardiol. 2011;107:1076–82.CrossRefPubMed Tancredi G, Versacci P, Pasquino AM, Vittucci AC, Pucarelli I, Cappa M, Di Mambro C, Marino B. Cardiopulmonary response to exercise and cardiac assessment in patients with Turner syndrome. Am J Cardiol. 2011;107:1076–82.CrossRefPubMed
17.
go back to reference Hallynck TH, Thomis JA, Daneels R, Dehli L. Should clearance be normalized to body surface area of lean body mass? Br J Clin Pharmacol. 1981;11:523–6.CrossRefPubMedPubMedCentral Hallynck TH, Thomis JA, Daneels R, Dehli L. Should clearance be normalized to body surface area of lean body mass? Br J Clin Pharmacol. 1981;11:523–6.CrossRefPubMedPubMedCentral
18.
go back to reference Work DF, Schwartz GJ. Estimating and measuring glomerular filtration rate in children. Curr Opin Nephrol Hypertens. 2008;17:320–5.CrossRefPubMed Work DF, Schwartz GJ. Estimating and measuring glomerular filtration rate in children. Curr Opin Nephrol Hypertens. 2008;17:320–5.CrossRefPubMed
19.
go back to reference Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, Mei Z, Curtin L, Roche A, Johnson CL. CDC Growth Charts: United states. Adv Data. 2000;314:1–28.PubMed Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, Mei Z, Curtin L, Roche A, Johnson CL. CDC Growth Charts: United states. Adv Data. 2000;314:1–28.PubMed
20.
go back to reference Beaufort-Krol GC, Dijkstra SS, Bink-Boelkens MT. Natural history of ventricular premature contractions in children with a structurally normal heart: does origin matter? Europace. 2008;10:998–1003.CrossRefPubMed Beaufort-Krol GC, Dijkstra SS, Bink-Boelkens MT. Natural history of ventricular premature contractions in children with a structurally normal heart: does origin matter? Europace. 2008;10:998–1003.CrossRefPubMed
21.
go back to reference Tancredi G, Quattrucci S, Scalercio F, De Castro G, Zicari AM, Bonci E, Cingolani S, Indinnimeo L, Midulla F. 3-Min step test and treadmill exercise for evaluating exercise-induced asthma. Eur Respir J. 2004;23:569–74.CrossRefPubMed Tancredi G, Quattrucci S, Scalercio F, De Castro G, Zicari AM, Bonci E, Cingolani S, Indinnimeo L, Midulla F. 3-Min step test and treadmill exercise for evaluating exercise-induced asthma. Eur Respir J. 2004;23:569–74.CrossRefPubMed
22.
go back to reference Villa MP, Rotili PL, Santamaria F, Vania A, Bonci E, Tancredi G, Ronchetti R. Physical performance in patients with thalassemia before and after transfusion. Pediatr Pulmonol. 1996;21:367–72.CrossRefPubMed Villa MP, Rotili PL, Santamaria F, Vania A, Bonci E, Tancredi G, Ronchetti R. Physical performance in patients with thalassemia before and after transfusion. Pediatr Pulmonol. 1996;21:367–72.CrossRefPubMed
23.
go back to reference Lubrano R, Travasso E, Raggi C, Guido G, Masciangelo R, Elli M. Blood pressure load, proteinuria and renal function in pre-hypertensive children. Pediatr Nephrol. 2009;24:823–31.CrossRefPubMed Lubrano R, Travasso E, Raggi C, Guido G, Masciangelo R, Elli M. Blood pressure load, proteinuria and renal function in pre-hypertensive children. Pediatr Nephrol. 2009;24:823–31.CrossRefPubMed
24.
go back to reference Brenner BM, Lawler EV, Mackenzie HS. The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int. 1996;49:1774–7.CrossRefPubMed Brenner BM, Lawler EV, Mackenzie HS. The hyperfiltration theory: a paradigm shift in nephrology. Kidney Int. 1996;49:1774–7.CrossRefPubMed
25.
go back to reference Moore SC, Patel AV, Matthews CE, Berrington de Gonzalez A, Park Y, Katki HA, Linet MS, Weiderpass E, Visvanathan K, Helzlsouer KJ, Thun M, Gapstur SM, Hartge P, Lee IM. Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mortality: A Large Pooled Cohort Analysis. PLoS Med. 2012;9:e1001335.CrossRefPubMedPubMedCentral Moore SC, Patel AV, Matthews CE, Berrington de Gonzalez A, Park Y, Katki HA, Linet MS, Weiderpass E, Visvanathan K, Helzlsouer KJ, Thun M, Gapstur SM, Hartge P, Lee IM. Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mortality: A Large Pooled Cohort Analysis. PLoS Med. 2012;9:e1001335.CrossRefPubMedPubMedCentral
27.
go back to reference Johansen KL, Painter P. Exercise in individuals with CKD. Am J Didney Dis. 2012;59:126–34.CrossRef Johansen KL, Painter P. Exercise in individuals with CKD. Am J Didney Dis. 2012;59:126–34.CrossRef
28.
go back to reference Garriguet D, Tremblay S, Colley RC. Comparison of Physical Activity Adult Questionnaire results with accelerometer data. Statistic Canada, Catalogue N.82-003. Health Report. 2015;26:11–7. Garriguet D, Tremblay S, Colley RC. Comparison of Physical Activity Adult Questionnaire results with accelerometer data. Statistic Canada, Catalogue N.82-003. Health Report. 2015;26:11–7.
29.
go back to reference Ottevaere C, Huybrechts I, De Bourdeaudhuij I, Sjöström M, Ruiz JR, Ortega FB, Hagströmer M, Widhalm K, Molnár D, Moreno LA, Beghin L, Kafatos A, Polito A, Manios Y, Mártinez-Gómez D, De Henauw S. Comparison of the IPAQ-A and actigraph in relation to VO2max among European adolescents: the HELENA study. J Sci Med Sport. 2011;14:317–24.CrossRefPubMed Ottevaere C, Huybrechts I, De Bourdeaudhuij I, Sjöström M, Ruiz JR, Ortega FB, Hagströmer M, Widhalm K, Molnár D, Moreno LA, Beghin L, Kafatos A, Polito A, Manios Y, Mártinez-Gómez D, De Henauw S. Comparison of the IPAQ-A and actigraph in relation to VO2max among European adolescents: the HELENA study. J Sci Med Sport. 2011;14:317–24.CrossRefPubMed
30.
go back to reference Jaoudé PA, Dubourg L, Bacchetta J, Berthiller J, Ranchin B, Cochat P. Congenital versus acquired solitary kidney: is the difference relevant? Nephrol Dial Transplant. 2011;26:2188–94.CrossRefPubMed Jaoudé PA, Dubourg L, Bacchetta J, Berthiller J, Ranchin B, Cochat P. Congenital versus acquired solitary kidney: is the difference relevant? Nephrol Dial Transplant. 2011;26:2188–94.CrossRefPubMed
31.
go back to reference Matthew M, Grinsell MD, Showalter S, et al. Single Kidney And Sports Partecipation: Perception versus Reality. Pediatrics. 2006;118:1019–27.CrossRef Matthew M, Grinsell MD, Showalter S, et al. Single Kidney And Sports Partecipation: Perception versus Reality. Pediatrics. 2006;118:1019–27.CrossRef
32.
go back to reference American Academy of Pediatrics Committee on Sports Medicine and Fitness. Medical conditions affecting sports participation. Pediatrics. 1994;94:757–60. American Academy of Pediatrics Committee on Sports Medicine and Fitness. Medical conditions affecting sports participation. Pediatrics. 1994;94:757–60.
33.
go back to reference Patel DP, Redshaw JD, Breyer BN, Smith TG, Erickson BA, Majercik SD, Gaither TW, Craig JR, Gardner S, Presson AP, Zhang C, Hotaling JM, Brant WO, Myers JB. High-grade renal injuries are often isolated in sports-related trauma. Injury. 2015;46:1245–9.CrossRefPubMed Patel DP, Redshaw JD, Breyer BN, Smith TG, Erickson BA, Majercik SD, Gaither TW, Craig JR, Gardner S, Presson AP, Zhang C, Hotaling JM, Brant WO, Myers JB. High-grade renal injuries are often isolated in sports-related trauma. Injury. 2015;46:1245–9.CrossRefPubMed
34.
go back to reference Johnson B, Christensen C, Dirusso S, Choudhury M, Franco I. A need for reevaluation of sports participation recommendations for children with a solitary kidney. J Urol. 2005;174:686–9.CrossRefPubMed Johnson B, Christensen C, Dirusso S, Choudhury M, Franco I. A need for reevaluation of sports participation recommendations for children with a solitary kidney. J Urol. 2005;174:686–9.CrossRefPubMed
35.
go back to reference Rice SG. American Academy of Pediatrics Council on Sports Medicine and Fitness. Medical conditions affecting sports participation. Pediatrics. 2008;121:841–8.CrossRefPubMed Rice SG. American Academy of Pediatrics Council on Sports Medicine and Fitness. Medical conditions affecting sports participation. Pediatrics. 2008;121:841–8.CrossRefPubMed
36.
go back to reference Giordano M. Participation in sports by children and adolescents with chronic kidney desease.G. Ital. Nefrol. 2012;29:328–32. Giordano M. Participation in sports by children and adolescents with chronic kidney desease.G. Ital. Nefrol. 2012;29:328–32.
37.
go back to reference Grinsell MM, Butz K, Gurka MJ, Gurka KK, Norwood V. Sport-Related Kidney Injury Among High School Athletes. Pediatrics. 2012;130:2011–82.CrossRef Grinsell MM, Butz K, Gurka MJ, Gurka KK, Norwood V. Sport-Related Kidney Injury Among High School Athletes. Pediatrics. 2012;130:2011–82.CrossRef
Metadata
Title
Cardiorespiratory fitness and sports activities in children and adolescents with solitary functioning kidney
Authors
Giancarlo Tancredi
Caterina Lambiase
Alessandra Favoriti
Francesca Ricupito
Sara Paoli
Marzia Duse
Giovanna De Castro
Anna Maria Zicari
Giovanna Vitaliti
Raffaele Falsaperla
Riccardo Lubrano
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue 1/2016
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/s13052-016-0255-6

Other articles of this Issue 1/2016

Italian Journal of Pediatrics 1/2016 Go to the issue