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Italian Journal of Pediatrics

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Open Access 01-12-2015 | Research

Neonatal blood stream infections in tertiary referral hospitals in Kurdistan, Iran

Authors: Bahram Nikkhoo, Fariba Lahurpur, Ali Delpisheh, Mohammad Aziz Rasouli, Abdorrahim Afkhamzadeh

Published in: Italian Journal of Pediatrics | Issue 1/2015

Abstract

Background

Bloodstream infection (BSI) is one of the most common causes of nosocomial infection in neonatal intensive care units (NICU). The aim of the present study was to determine bacterial agents and their susceptibility patterns to antibiotics and to investigate the risk factors associated with BSI.

Methods

This was a nested case–control study carried out from September 2009 to June 2010 in the NICU wards in Sanandaj hospitals western Iran. Cases were patients with BSI and controls were other patients who had negative blood culture. Bacteriologic diagnosis and antibiotic susceptibility pattern was performed based on the Edward & Ewings and the National Committee of Clinical Laboratory (NCCL) Standards.

Results

Of 472 patients who hospitalized in NICU, 6.4% had BSI (n = 30) including 17girls (56.7%) and 13 boys (43.3%). Enterobacter SPP was the predominant isolated bacteria from blood culture (36.7%). The maximum antibiotic resistance and sensitivity were observed by Tetracycline and Ciprofloxacin respectively. Risk factors associated with BSI were age ≤ 7 days (p = 0.001), previous antibiotic consumption (p = 0.013), and low birth weight (LBW), (p = 0.001).

Conclusions

Gram negative bacteria and Entrobacter in particular are the most common pathogens. Improving prenatal health care, standards of infection control and choosing accurate antibiotics are recommended to avoid BSI in neonatal intensive care units.

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Title: Neonatal blood stream infections in tertiary referral hospitals in Kurdistan, Iran
Authors: Bahram Nikkhoo
Fariba Lahurpur
Ali Delpisheh
Mohammad Aziz Rasouli
Abdorrahim Afkhamzadeh
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Italian Journal of Pediatrics / Issue 1/2015
Electronic ISSN: 1824-7288
DOI: https://doi.org/10.1186/s13052-015-0136-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Neonatal blood stream infections in tertiary referral hospitals in Kurdistan, Iran

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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