Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2016

Open Access 01-12-2016 | Study protocol

The ReCaPTa study - a prospective out of hospital cardiac arrest registry including multiple sources of surveillance for the study of sudden cardiac death in the Mediterranean area

Authors: Youcef Azeli, Eneko Barbería, María Jiménez-Herrera, Gil Bonet, Eva Valero-Mora, Alfonso Lopez-Gomariz, Isaac Lucas-Guarque, Alex Guillen-Lopez, Carlos Alonso-Villaverde, Inés Landín, Pilar Torralba, Ali Jammoul, Jordi Bladé-Creixenti, Christer Axelsson, Alfredo Bardají

Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | Issue 1/2016

Login to get access

Abstract

Background

Cardiovascular diseases are one of the leading causes of death in the industrialized world. Sudden cardiac death is very often the first manifestation of the disease and it occurs in the prehospital setting.
The determination of the sudden cardiac death phenotype is challenging. It requires prospective studies in the community including multiple sources of case ascertainment that help to identify the cause and circumstances of death.
The aim of the Clinical and Pathological Registry of Tarragona (ReCaPTa) is to study incidence and etiology of Sudden Cardiac Death in the Tarragona region (Catalonia, Spain).

Methods

ReCaPTa is a population-based registry of OHCA using multiple sources of surveillance. The population base is 511,662. This registry is compiled chronologically in a relational database and it prospectively contains data on all the OHCA attended by the EMS from April 2014 to April 2017. ReCaPTa collects data after each emergency medical assistance using an online application including variables of the onset of symptoms. A quality control is performed and it permits monitoring the percentage of cases included by the emergency crew. Simultaneously, data from the medico-legal autopsies is taken from the Pathology Center of the area. All the examination findings following a specific protocol for the sudden death study are entered into the ReCaPTa database by one trained person. Survivors admitted to hospital are followed up and their clinical variables are collected in each hospital. The primary care researchers analyze the digital clinical records in order to obtain medical background. All the available data will be reviewed after an adjudication process with the aim of identifying all cases of sudden cardiac death.

Discussion

There is a lack of population-based registries including multiple source of surveillance in the Mediterranean area. The ReCaPTa study could provide valuable information to prevent sudden cardiac death and develop new strategies to improve its survival.
Literature
1.
Atwood C, Eisenberg MS, Herlitz J, Rea TD. Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. Resuscitation. 2005;67:75–80.CrossRefPubMed
2.
Berdowski J, Berg RA, Tijssen JGP, Koster RW. Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies. Resuscitation. 2010;81:1479–87.CrossRefPubMed
3.
4.
WHO. World health statistics annual. Geneva: World Health Organization; 1998.
5.
Lahti RA, Penttilä A. The validity of death certificates: routine validation of death certification and its effects on mortality statistics. Forensic Sci Int. 2001;115:15–32.CrossRefPubMed
6.
Chugh SS, Jui J, Gunson K, Stecker EC, John BT, Thompson B, et al. Current burden of sudden cardiac death: Multiple source surveillance versus retrospective death certificate-based review in a large U.S. community. J Am Coll Cardiol. 2004;44:1268–75.CrossRefPubMed
7.
Chugh SS, Reinier K, Teodorescu C, Evanado A, Kehr E, Al Samara M, et al. Epidemiology of Sudden Cardiac Death: Clinical and Research Implications. Prog Cardiovasc Dis. 2008;51:213–28.CrossRefPubMedPubMedCentral
8.
Bardají A. REGICOR: 35 años de excelencia en investigación cardiovascular. Rev Esp Cardiol. 2013;66:923–5.CrossRefPubMed
9.
Fishman GI, Chugh SS, DiMarco JP, Albert CM, Anderson ME, Bonow RO, et al. Sudden Cardiac Death Prediction and Prevention: Report From a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop. Circulation. 2010;122:2335–48.CrossRefPubMedPubMedCentral
10.
Byrne R, Constant O, Smyth Y, Callagy G, Nash P, Daly K, et al. Multiple source surveillance incidence and aetiology of out-of-hospital sudden cardiac death in a rural population in the West of Ireland. Eur Heart J. 2008;29:1418–23.CrossRefPubMed
11.
Narayanan K, Zhang L, Kim C, Uy-Evanado A, Teodorescu C, Reinier K, et al. QRS Fragmentation and Sudden Cardiac Death in the Obese and Overweight. J Am Heart Assoc. 2015;4:e001654.CrossRefPubMedPubMedCentral
12.
Hua W, Zhang L-F, Wu Y-F, Liu X-Q, Guo D-S, Zhou H-L, et al. Incidence of sudden cardiac death in China: analysis of 4 regional populations. J Am Coll Cardiol. 2009;54:1110–8.CrossRefPubMed
13.
Perkins GD, Jacobs IG, Nadkarni VM, Berg RA, Bhanji F, Biarent D, et al. Cardiac arrest and cardiopulmonary resuscitation outcome reports: Update of the Utstein resuscitation registry templates for out-of-hospital cardiac arrest. Resuscitation. 2015;96:328–40.CrossRefPubMed
14.
Jacobs I. Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update and Simplification of the Utstein Templates for Resuscitation Registries: A Statement for Healthcare Professionals From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Council, New Zealand Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Councils of Southern Africa). Circulation. 2004;110:3385–97.CrossRefPubMed
15.
16.
17.
del Águila JG, López-Messa J, Rosell-Ortiz F, de Elías HR, del Valle MM, Sánchez-Santos L, et al. Recomendaciones para el soporte telefónico a la reanimación por testigos desde los centros de coordinación de urgencias y emergencias. Med Intensiva. 2015;39:298–302.CrossRef
18.
Barbería E, Xifró A, Suelves JM, Arimany J. La proyección social y sanitaria de los institutos de medicina legal en España: más allá de la justicia. Med Clin (Barc). 2014;142 Suppl 2:3–13.
19.
20.
Azeli Y, Barbería E, Landín I, Torralba P, Amaya C, Laguna C. Lesiones por reanimación cardiopulmonar en autopsias forenses: protocolo del Registro Clínico-Patológico de Tarragona (ReCaPTa). Rev Esp Med Legal. 2016;42:120–5.
21.
Deakin CD, Morrison LJ, Morley PT, Callaway CW, Kerber RE, Kronick SL, et al. Part 8: Advanced life support. Resuscitation. 2010;81:e93–174.CrossRefPubMed
22.
Zipes DP, Camm AJ, Borggrefe M, Buxton AE, Chaitman B, Fromer M, et al. ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death. J Am Coll Cardiol. 2006;48:e247–346.CrossRefPubMed
23.
Jiménez-Herrera MF, Azeli Y, Mora EV, Lucas-Guarque I, López-Gomariz A, Castro-Naval E, et al. Passive leg raise (PLR) during cardiopulmonary (CPR)-a method article on a randomised study of survival in out-of-hospital cardiac arrest (OHCA). BMC Emerg Med. 2014;14:15.CrossRefPubMedPubMedCentral
24.
25.
Rosell-Ortiz FR, Mellado-Vergel FM, Fernandez-Valle PF, Gonzalez-lobato IG, Martinez-Lara M, et al. Descripción y resultados iniciales del registro andaluz de parada cardiaca extrahospitalaria. Emergencias. 2013;25:345–52.
26.
Kitamura T, Kiyohara K, Sakai T, Iwami T, Nishiyama C, Kajino K, et al. Epidemiology and outcome of adult out-of-hospital cardiac arrest of non-cardiac origin in Osaka: a population-based study. BMJ Open. 2014;4:e006462.CrossRefPubMedPubMedCentral
27.
McNally B, Stokes A, Crouch A, Kellermann AL. CARES: Cardiac Arrest Registry to Enhance Survival. Ann Emerg Med. 2009;54:674–83.e2.CrossRefPubMed
28.
Weisfeldt ML, Sitlani CM, Ornato JP, Rea T, Aufderheide TP, Davis D, et al. Survival After Application of Automatic External Defibrillators Before Arrival of the Emergency Medical System. J Am Coll Cardiol. 2010;55:1713–20.CrossRefPubMedPubMedCentral
29.
Nishiyama C, Brown SP, May S, Iwami T, Koster RW, Beesems SG, et al. Apples to apples or apples to oranges? International variation in reporting of process and outcome of care for out-of-hospital cardiac arrest. Resuscitation. 2014;85:1599–609.CrossRefPubMedPubMedCentral
30.
Strömsöe A, Svensson L, Axelsson AB, Göransson K, Todorova L, Herlitz J. Validity of reported data in the Swedish Cardiac Arrest Register in selected parts in Sweden. Resuscitation. 2013;84:952–6.CrossRefPubMed
31.
de Vreede-Swagemakers JJ, Gorgels AP, Dubois-Arbouw WI, van Ree JW, Daemen MJ, Houben LG, et al. Out-of-hospital cardiac arrest in the 1990s: a population-based study in the Maastricht area on incidence, characteristics and survival. J Am Coll Cardiol. 1997;30:1500–5.CrossRefPubMed
32.
Burke AP, Farb A, Malcom GT, Liang Y, Smialek J, Virmani R. Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. N Engl J Med. 1997;336:1276–82.CrossRefPubMed
33.
Chugh SS, Uy-Evanado A, Teodorescu C, Reinier K, Mariani R, Gunson K, et al. Women Have a Lower Prevalence of Structural Heart Disease as a Precursor to Sudden Cardiac Arrest. J Am Coll Cardiol. 2009;54:2006–11.CrossRefPubMedPubMedCentral
34.
Subirana MT, Juan-Babot JO, Puig T, Lucena J, Rico A, Salguero M, et al. Specific Characteristics of Sudden Death in a Mediterranean Spanish Population. Am J Cardiol. 2011;107:622–7.CrossRefPubMed
35.
36.
Marrugat J, Elosua R, Gil M. Sudden cardiac death epidemiology in Spain. Rev Esp Cardiol. 1999;52:717–25.CrossRefPubMed
37.
Kannel WB, Gagnon DR, Cupples LA. Epidemiology of sudden coronary death: population at risk. Can J Cardiol. 1990;6:439–44.PubMed
38.
Fox CS. Temporal Trends in Coronary Heart Disease Mortality and Sudden Cardiac Death From 1950 to 1999: The Framingham Heart Study. Circulation. 2004;110:522–7.CrossRefPubMed
39.
Sans S. Increasing trends of acute myocardial infarction in Spain: the MONICA-Catalonia Study. Eur Heart J. 2004;26:505–15.CrossRefPubMed
40.
Cobb LA, Fahrenbruch CE, Olsufka M, Copass MK. Changing Incidence of Out-of-Hospital Ventricular Fibrillation, 1980-2000. JAMA. 2002;288:3008–13.
41.
Myerburg RJ, Reddy V, Castellanos A. Indications for Implantable Cardioverter-Defibrillators Based on Evidence and Judgment. J Am Coll Cardiol. 2009;54:747–63.CrossRefPubMed
Metadata
Title
The ReCaPTa study - a prospective out of hospital cardiac arrest registry including multiple sources of surveillance for the study of sudden cardiac death in the Mediterranean area
Authors
Youcef Azeli
Eneko Barbería
María Jiménez-Herrera
Gil Bonet
Eva Valero-Mora
Alfonso Lopez-Gomariz
Isaac Lucas-Guarque
Alex Guillen-Lopez
Carlos Alonso-Villaverde
Inés Landín
Pilar Torralba
Ali Jammoul
Jordi Bladé-Creixenti
Christer Axelsson
Alfredo Bardají
Publication date
01-12-2016
Publisher
BioMed Central
DOI
https://doi.org/10.1186/s13049-016-0309-1

Other articles of this Issue 1/2016

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2016 Go to the issue

Original research

Surgical intervention for paediatric liver injuries is almost history - a 12-year cohort from a major Scandinavian trauma centre

Original research

Geographic information system data from ambulances applied in the emergency department: effects on patient reception

Original research

The association between vital signs and mortality in a retrospective cohort study of an unselected emergency department population

Original research

Fibrinogen levels in trauma patients during the first seven days after fibrinogen concentrate therapy: a retrospective study

Original research

Combining the new injury severity score with an anatomical polytrauma injury variable predicts mortality better than the new injury severity score and the injury severity score: a retrospective cohort study

Original research

Heel pressure ulcer, prevention and predictors during the care delivery chain – when and where to take action? A descriptive and explorative study