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Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 1/2015

Open Access 01-12-2015 | Original research

Difficult intubation and outcome after out-of-hospital cardiac arrest: a registry-based analysis

Authors: Jan Wnent, Rüdiger Franz, Stephan Seewald, Rolf Lefering, Matthias Fischer, Andreas Bohn, Jörg W. Walther, Jens Scholz, Roman-Patrik Lukas, Jan-Thorsten Gräsner, the German Resuscitation Registry Study Group

Published in: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | Issue 1/2015

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Abstract

Background

Airway management during resuscitation attempts is pivotal for treating hypoxia, and endotracheal intubation is the standard procedure. This German Resuscitation Registry analysis investigates the influence of airway management on primary outcomes after out-of-hospital cardiac arrest, in a physician-based emergency system.

Methods

A total of 8512 patients recorded in the German Resuscitation Registry (2007–2011) were analyzed. The Return of Spontaneous Circulation After Cardiac Arrest (RACA) score was used to compare observed return of spontaneous circulation (ROSC) rates with the ROSC predicted by the score and to analyze factors influencing the primary outcome. Patients were classified into three groups: difficult intubation, impossible intubation, and a control group with normal airways.

Results

The observed ROSC matched the predicted ROSC in the group with difficult airways. The impossible intubation group had lower ROSC rates (31.3 % vs. 40.5 %; P < 0.05). Impossible intubation was more frequent in men (OR 2.28; 95 % CI, 1.43–3.63; P = 0.001), young patients (OR 2.18; 95 % CI, 1.26–3.76; P = 0.005) and those with trauma (OR 2.22; 95 % CI, 1.01–4.85; P = 0.046). Fewer impossible intubations were reported when the emergency physicians were anesthesiologists (OR 0.65; 95 % CI, 0.44–0.96; P = 0.028). If a supraglottic airway device was not used in the impossible intubation group, the observed ROSC (18.0 %; 95 % CI, 7.4–28.6 %) was poorer than predicted (38.2 %) (P < 0.05).

Conclusions

Outcomes after resuscitation attempts are poorer when endotracheal intubation is not possible. Predictive factors for impossible intubation are male gender, younger age, and trauma. Supraglottic airway devices should be used at an early stage whenever these negative factors are present.
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Literature
1.
go back to reference Fernandez Castelao E, Russo SG, Cremer S, et al. Positive impact of crisis resource management training on no-flow time and team member verbalisations during simulated cardiopulmonary resuscitation: a randomised controlled trial. Resuscitation. 2011;82:1338–43.PubMedCrossRef Fernandez Castelao E, Russo SG, Cremer S, et al. Positive impact of crisis resource management training on no-flow time and team member verbalisations during simulated cardiopulmonary resuscitation: a randomised controlled trial. Resuscitation. 2011;82:1338–43.PubMedCrossRef
2.
go back to reference Martin-Hernandez H, Lopez-Messa JB, Perez-Vela JL, Herrero-Ansola P. ILCOR 2010 recommendations. The evidence evaluation process in resuscitation. Med Intensiva. 2011;35:249–55.PubMedCrossRef Martin-Hernandez H, Lopez-Messa JB, Perez-Vela JL, Herrero-Ansola P. ILCOR 2010 recommendations. The evidence evaluation process in resuscitation. Med Intensiva. 2011;35:249–55.PubMedCrossRef
3.
go back to reference Olasveengen TM, Vik E, Kuzovlev A, Sunde K. Effect of implementation of new resuscitation guidelines on quality of cardiopulmonary resuscitation and survival. Resuscitation. 2009;80:407–11.PubMedCrossRef Olasveengen TM, Vik E, Kuzovlev A, Sunde K. Effect of implementation of new resuscitation guidelines on quality of cardiopulmonary resuscitation and survival. Resuscitation. 2009;80:407–11.PubMedCrossRef
4.
go back to reference Lund-Kordahl I, Olasveengen TM, Lorem T, Samdal M, Wik L, Sunde K. Improving outcome after out-of-hospital cardiac arrest by strengthening weak links of the local chain of survival; quality of advanced life support and post-resuscitation care. Resuscitation. 2010;81:422–6.PubMedCrossRef Lund-Kordahl I, Olasveengen TM, Lorem T, Samdal M, Wik L, Sunde K. Improving outcome after out-of-hospital cardiac arrest by strengthening weak links of the local chain of survival; quality of advanced life support and post-resuscitation care. Resuscitation. 2010;81:422–6.PubMedCrossRef
5.
go back to reference Deakin CD, Nolan JP, Soar J, et al. European resuscitation council guidelines for resuscitation 2010 section 4. Adult advanced life support. Resuscitation. 2010;81:1305–52.PubMedCrossRef Deakin CD, Nolan JP, Soar J, et al. European resuscitation council guidelines for resuscitation 2010 section 4. Adult advanced life support. Resuscitation. 2010;81:1305–52.PubMedCrossRef
6.
go back to reference Timmermann A. Modern airway management–current concepts for more patient safety. Anasthesiol Intensivmed Notfallmed Schmerzther. 2009;44:246–55.PubMedCrossRef Timmermann A. Modern airway management–current concepts for more patient safety. Anasthesiol Intensivmed Notfallmed Schmerzther. 2009;44:246–55.PubMedCrossRef
7.
go back to reference Timmermann A, Braun U, Panzer W, Schlaeger M, Schnitzker M. Graf BM [Out-of-hospital airway management in northern Germany. Physician-specific knowledge, procedures and equipment].. Anaesthesist. 2007;56:328–34.PubMedCrossRef Timmermann A, Braun U, Panzer W, Schlaeger M, Schnitzker M. Graf BM [Out-of-hospital airway management in northern Germany. Physician-specific knowledge, procedures and equipment].. Anaesthesist. 2007;56:328–34.PubMedCrossRef
8.
go back to reference Timmermann A, Eich C, Russo SG, et al. Prehospital airway management: a prospective evaluation of anaesthesia trained emergency physicians. Resuscitation. 2006;70:179–85.PubMedCrossRef Timmermann A, Eich C, Russo SG, et al. Prehospital airway management: a prospective evaluation of anaesthesia trained emergency physicians. Resuscitation. 2006;70:179–85.PubMedCrossRef
9.
go back to reference Timmermann A, Russo SG, Eich C, et al. The out-of-hospital esophageal and endobronchial intubations performed by emergency physicians. Anesth Analg. 2007;104:619–23.PubMedCrossRef Timmermann A, Russo SG, Eich C, et al. The out-of-hospital esophageal and endobronchial intubations performed by emergency physicians. Anesth Analg. 2007;104:619–23.PubMedCrossRef
10.
go back to reference Engdahl J, Holmberg M, Karlson BW, Luepker R, Herlitz J. The epidemiology of out-of-hospital ‘sudden’ cardiac arrest. Resuscitation. 2002;52:235–45.PubMedCrossRef Engdahl J, Holmberg M, Karlson BW, Luepker R, Herlitz J. The epidemiology of out-of-hospital ‘sudden’ cardiac arrest. Resuscitation. 2002;52:235–45.PubMedCrossRef
11.
go back to reference Herlitz J, Bahr J, Fischer M, Kuisma M, Lexow K, Thorgeirsson G. Resuscitation in Europe: a tale of five European regions. Resuscitation. 1999;41:121–31.PubMedCrossRef Herlitz J, Bahr J, Fischer M, Kuisma M, Lexow K, Thorgeirsson G. Resuscitation in Europe: a tale of five European regions. Resuscitation. 1999;41:121–31.PubMedCrossRef
12.
go back to reference Krittayaphong R, Saengsung P, Chawaruechai T, Yindeengam A, Udompunturak S. Factors predicting outcome of cardiopulmonary resuscitation in a developing country: the Siriraj cardiopulmonary resuscitation registry. J Med Assoc Thai. 2009;92:618–23.PubMed Krittayaphong R, Saengsung P, Chawaruechai T, Yindeengam A, Udompunturak S. Factors predicting outcome of cardiopulmonary resuscitation in a developing country: the Siriraj cardiopulmonary resuscitation registry. J Med Assoc Thai. 2009;92:618–23.PubMed
13.
go back to reference Gräsner JT, Meybohm P, Lefering R, et al. ROSC after cardiac arrest–the RACA score to predict outcome after out-of-hospital cardiac arrest. Eur Heart J. 2011;32:1649–56.PubMedCrossRef Gräsner JT, Meybohm P, Lefering R, et al. ROSC after cardiac arrest–the RACA score to predict outcome after out-of-hospital cardiac arrest. Eur Heart J. 2011;32:1649–56.PubMedCrossRef
14.
go back to reference Gräsner JT, Wnent J, Seewald S, et al. Cardiopulmonary resuscitation traumatic cardiac arrest - there are survivors. An analysis of two national emergency registries. Crit Care. 2011;15:R276.PubMedCentralPubMedCrossRef Gräsner JT, Wnent J, Seewald S, et al. Cardiopulmonary resuscitation traumatic cardiac arrest - there are survivors. An analysis of two national emergency registries. Crit Care. 2011;15:R276.PubMedCentralPubMedCrossRef
15.
go back to reference Herlitz J, Engdahl J, Svensson L, Young M, Angquist KA, Holmberg S. Can we define patients with no chance of survival after out-of-hospital cardiac arrest? Heart. 2004;90:1114–8.PubMedCentralPubMedCrossRef Herlitz J, Engdahl J, Svensson L, Young M, Angquist KA, Holmberg S. Can we define patients with no chance of survival after out-of-hospital cardiac arrest? Heart. 2004;90:1114–8.PubMedCentralPubMedCrossRef
16.
go back to reference Herlitz J, Svensson L, Engdahl J, et al. Characteristics of cardiac arrest and resuscitation by age group: an analysis from the Swedish cardiac arrest registry. Am J Emerg Med. 2007;25:1025–31.PubMedCrossRef Herlitz J, Svensson L, Engdahl J, et al. Characteristics of cardiac arrest and resuscitation by age group: an analysis from the Swedish cardiac arrest registry. Am J Emerg Med. 2007;25:1025–31.PubMedCrossRef
17.
go back to reference Sasson C, Rogers MA, Dahl J, Kellermann AL. Predictors of survival from out-of-hospital cardiac arrest: a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes. 2010;3:63–81.PubMedCrossRef Sasson C, Rogers MA, Dahl J, Kellermann AL. Predictors of survival from out-of-hospital cardiac arrest: a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes. 2010;3:63–81.PubMedCrossRef
18.
go back to reference Gräsner JT, Meybohm P, Fischer M, et al. A national resuscitation registry of out-of-hospital cardiac arrest in Germany-a pilot study. Resuscitation. 2009;80:199–203.PubMedCrossRef Gräsner JT, Meybohm P, Fischer M, et al. A national resuscitation registry of out-of-hospital cardiac arrest in Germany-a pilot study. Resuscitation. 2009;80:199–203.PubMedCrossRef
19.
go back to reference Jacobs I, Nadkarni V, Bahr J, et al. Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries. A statement for healthcare professionals from a task force of the international liaison committee on resuscitation (american heart association, european resuscitation council, Australian resuscitation council, New Zealand resuscitation council, heart and stroke foundation of Canada, InterAmerican heart foundation, resuscitation council of southern africa). Resuscitation. 2004;63:233–49.PubMedCrossRef Jacobs I, Nadkarni V, Bahr J, et al. Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries. A statement for healthcare professionals from a task force of the international liaison committee on resuscitation (american heart association, european resuscitation council, Australian resuscitation council, New Zealand resuscitation council, heart and stroke foundation of Canada, InterAmerican heart foundation, resuscitation council of southern africa). Resuscitation. 2004;63:233–49.PubMedCrossRef
20.
go back to reference Zaritsky A, Nadkarni V, Hazinski MF, et al. Recommended guidelines for uniform reporting of pediatric advanced life support: the pediatric Utstein style. A statement for healthcare professionals from a task force of the American academy of pediatrics, the american heart association, and the European resuscitation council. Resuscitation. 1995;30:95–115.PubMedCrossRef Zaritsky A, Nadkarni V, Hazinski MF, et al. Recommended guidelines for uniform reporting of pediatric advanced life support: the pediatric Utstein style. A statement for healthcare professionals from a task force of the American academy of pediatrics, the american heart association, and the European resuscitation council. Resuscitation. 1995;30:95–115.PubMedCrossRef
21.
go back to reference Gräsner JT, Herlitz J, Koster RW, Rosell-Ortiz F, Stamatakis L, Bossaert L. Quality management in resuscitation–towards a European cardiac arrest registry (EuReCa). Resuscitation. 2011;82:989–94.PubMedCrossRef Gräsner JT, Herlitz J, Koster RW, Rosell-Ortiz F, Stamatakis L, Bossaert L. Quality management in resuscitation–towards a European cardiac arrest registry (EuReCa). Resuscitation. 2011;82:989–94.PubMedCrossRef
22.
go back to reference Chamberlain D, Cummins RO. Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the ‘Utstein style’. European resuscitation council, american heart association, heart and stroke foundation of Canada and Australian resuscitation council. Eur J Anaesthesiol. 1992;9:245–56.PubMed Chamberlain D, Cummins RO. Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the ‘Utstein style’. European resuscitation council, american heart association, heart and stroke foundation of Canada and Australian resuscitation council. Eur J Anaesthesiol. 1992;9:245–56.PubMed
23.
go back to reference Breckwoldt J, Klemstein S, Brunne B, Schnitzer L, Mochmann HC, Arntz HR. Difficult prehospital endotracheal intubation - predisposing factors in a physician based EMS. Resuscitation. 2011;82:1519–24.PubMedCrossRef Breckwoldt J, Klemstein S, Brunne B, Schnitzer L, Mochmann HC, Arntz HR. Difficult prehospital endotracheal intubation - predisposing factors in a physician based EMS. Resuscitation. 2011;82:1519–24.PubMedCrossRef
24.
go back to reference Cobas MA, De la Pena MA, Manning R, Candiotti K, Varon AJ. Prehospital intubations and mortality: a level 1 trauma center perspective. Anesth Analg. 2009;109:489–93.PubMedCrossRef Cobas MA, De la Pena MA, Manning R, Candiotti K, Varon AJ. Prehospital intubations and mortality: a level 1 trauma center perspective. Anesth Analg. 2009;109:489–93.PubMedCrossRef
25.
go back to reference Wang HE, Kupas DF, Greenwood MJ, et al. An algorithmic approach to prehospital airway management. Prehosp Emerg Care. 2005;9:145–55.PubMedCrossRef Wang HE, Kupas DF, Greenwood MJ, et al. An algorithmic approach to prehospital airway management. Prehosp Emerg Care. 2005;9:145–55.PubMedCrossRef
26.
go back to reference Breckwoldt J, Klemstein S, Brunne B, Schnitzer L, Arntz HR, Mochmann HC. Expertise in prehospital endotracheal intubation by emergency medicine physicians-comparing ‘proficient performers’ and ‘experts’. Resuscitation. 2012;83:434–9.PubMedCrossRef Breckwoldt J, Klemstein S, Brunne B, Schnitzer L, Arntz HR, Mochmann HC. Expertise in prehospital endotracheal intubation by emergency medicine physicians-comparing ‘proficient performers’ and ‘experts’. Resuscitation. 2012;83:434–9.PubMedCrossRef
27.
go back to reference Chenaitia H, Soulleihet V, Massa H, et al. The Easytube for airway management in prehospital emergency medicine. Resuscitation. 2010;81:1516–20.PubMedCrossRef Chenaitia H, Soulleihet V, Massa H, et al. The Easytube for airway management in prehospital emergency medicine. Resuscitation. 2010;81:1516–20.PubMedCrossRef
28.
go back to reference Adnet F, Jouriles NJ, Le Toumelin P, et al. Survey of out-of-hospital emergency intubations in the French prehospital medical system: a multicenter study. Ann Emerg Med. 1998;32:454–60.PubMedCrossRef Adnet F, Jouriles NJ, Le Toumelin P, et al. Survey of out-of-hospital emergency intubations in the French prehospital medical system: a multicenter study. Ann Emerg Med. 1998;32:454–60.PubMedCrossRef
29.
go back to reference Burkle CM, Walsh MT, Harrison BA, Curry TB, Rose SH. Airway management after failure to intubate by direct laryngoscopy: outcomes in a large teaching hospital. Can J Anaesth. 2005;52:634–40.PubMedCrossRef Burkle CM, Walsh MT, Harrison BA, Curry TB, Rose SH. Airway management after failure to intubate by direct laryngoscopy: outcomes in a large teaching hospital. Can J Anaesth. 2005;52:634–40.PubMedCrossRef
30.
go back to reference Thierbach A, Piepho T, Wolcke B, Kuster S, Dick W. Prehospital emergency airway management procedures. Success rates and complications. Anaesthesist. 2004;53:543–50.PubMedCrossRef Thierbach A, Piepho T, Wolcke B, Kuster S, Dick W. Prehospital emergency airway management procedures. Success rates and complications. Anaesthesist. 2004;53:543–50.PubMedCrossRef
31.
go back to reference Dengler V, Wilde P, Byhahn C, Mack MG, Schalk R. Prehospital airway management of laryngeal tubes. Should the laryngeal tube S with gastric drain tube be preferred in emergency medicine? Anaesthesist. 2011;60:135–8.PubMedCrossRef Dengler V, Wilde P, Byhahn C, Mack MG, Schalk R. Prehospital airway management of laryngeal tubes. Should the laryngeal tube S with gastric drain tube be preferred in emergency medicine? Anaesthesist. 2011;60:135–8.PubMedCrossRef
32.
go back to reference Schalk R, Auhuber T, Haller O, et al. Implementation of the laryngeal tube for prehospital airway management: training of 1,069 emergency physicians and paramedics. Anaesthesist. 2012;61:35–40.PubMedCrossRef Schalk R, Auhuber T, Haller O, et al. Implementation of the laryngeal tube for prehospital airway management: training of 1,069 emergency physicians and paramedics. Anaesthesist. 2012;61:35–40.PubMedCrossRef
33.
go back to reference Yanagawa Y, Sakamoto T. Analysis of prehospital care for cardiac arrest in an urban setting in Japan. J Emerg Med. 2010;38:340–5.PubMedCrossRef Yanagawa Y, Sakamoto T. Analysis of prehospital care for cardiac arrest in an urban setting in Japan. J Emerg Med. 2010;38:340–5.PubMedCrossRef
34.
go back to reference Dumas F, Cariou A, Manzo-Silberman S, et al. Immediate percutaneous coronary intervention is associated with better survival after out-of-hospital cardiac arrest: insights from the PROCAT (Parisian region Out of hospital cardiac ArresT) registry. Circ Cardiovasc Interv. 2010;3:200–7.PubMedCrossRef Dumas F, Cariou A, Manzo-Silberman S, et al. Immediate percutaneous coronary intervention is associated with better survival after out-of-hospital cardiac arrest: insights from the PROCAT (Parisian region Out of hospital cardiac ArresT) registry. Circ Cardiovasc Interv. 2010;3:200–7.PubMedCrossRef
Metadata
Title
Difficult intubation and outcome after out-of-hospital cardiac arrest: a registry-based analysis
Authors
Jan Wnent
Rüdiger Franz
Stephan Seewald
Rolf Lefering
Matthias Fischer
Andreas Bohn
Jörg W. Walther
Jens Scholz
Roman-Patrik Lukas
Jan-Thorsten Gräsner
the German Resuscitation Registry Study Group
Publication date
01-12-2015
Publisher
BioMed Central
DOI
https://doi.org/10.1186/s13049-015-0124-0

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