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Published in: Journal of Ovarian Research 1/2018

Open Access 01-12-2018 | Research

Does a poor-quality embryo have an adverse impact on a good-quality embryo when transferred together?

Authors: Jiaheng Li, Mingze Du, Zhan Zhang, Yichun Guan, Xingling Wang, Xiao Zhang, Jing Liu, Zhouhui Pan, Bijun Wang, Wenxia Liu

Published in: Journal of Ovarian Research | Issue 1/2018

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Abstract

Background

In some in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles, we may consider transferring one poor-quality embryo with one good-quality embryo. Previous studies have indicated that the poor-quality embryo transferred with a good-quality embryo does not negatively affect the clinical pregnancy rate or live birth rate. The purpose of this study was to evaluate pregnancy outcomes and neonatal outcomes in this context.

Methods

This was a retrospective study that included 1646 cycles from our centre. Patients were divided into two groups (group A: one good-quality embryo was transferred with one poor-quality embryo; group B: two good-quality embryos were transferred). The primary outcomes were the clinical pregnancy rate and live birth rate. Additionally, we investigated the implantation rate, ectopic pregnancy rate, abortion rate, multiple pregnancy rate, birthweight and gestational age.

Results

We found that there were no differences in the clinical pregnancy rate and live birth rate between group A and group B. However, the implantation rate and multiple pregnancy rate were higher in group B than in group A.

Conclusions

The poor-quality embryo does not have a significant influence on the good-quality embryo when transferred together.
Literature
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go back to reference Ziebe S, et al. Embryo morphology or cleavage stage: how to select the best embryos for transfer after in-vitro fertilization. Human Reprod. 1997;12:1545–9.CrossRef Ziebe S, et al. Embryo morphology or cleavage stage: how to select the best embryos for transfer after in-vitro fertilization. Human Reprod. 1997;12:1545–9.CrossRef
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go back to reference El-Danasouri I, et al. Effect of transferring a morphologically impaired embryo with a good quality embryo on the pregnancy and implantation rates. Eur Rev Med Pharmacol Sci. 2016;20:394–8.PubMed El-Danasouri I, et al. Effect of transferring a morphologically impaired embryo with a good quality embryo on the pregnancy and implantation rates. Eur Rev Med Pharmacol Sci. 2016;20:394–8.PubMed
Metadata
Title
Does a poor-quality embryo have an adverse impact on a good-quality embryo when transferred together?
Authors
Jiaheng Li
Mingze Du
Zhan Zhang
Yichun Guan
Xingling Wang
Xiao Zhang
Jing Liu
Zhouhui Pan
Bijun Wang
Wenxia Liu
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Ovarian Research / Issue 1/2018
Electronic ISSN: 1757-2215
DOI
https://doi.org/10.1186/s13048-018-0452-6

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