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Published in: Child and Adolescent Psychiatry and Mental Health 1/2020

01-12-2020 | Disturbance of the Social Behaviour | Research article

Comorbidity of disruptive behavior disorders and intermittent explosive disorder

Authors: Karam Radwan, Emil F. Coccaro

Published in: Child and Adolescent Psychiatry and Mental Health | Issue 1/2020

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Abstract

Background

Aggressive behavior in children and adolescents may be accounted for by several disruptive behavioral disorders (DBD) including attention-deficit/hyperactive (ADHD), conduct (CD), and oppositional defiant (ODD), disorders and intermittent explosive disorder (IED). The comorbidity among the DBDs is well known, but not its comorbidity with IED.

Method

We reanalyzed data from the National Comorbidity Studies (adolescents and adults), and from a large clinical research adult sample, to estimate the comorbidity of IED with each of the DBDs and to explore correlates of these comorbidities.

Results

The rate of current comorbidity between IED and the DBDs ranged from 10 to 19%, in adolescents (5–14% in adults) with odds ratios of about five. The onset of ADHD typically appeared before onset of IED while onset ODD and CD more typically appeared before that of IED in adolescents and about equally before or after IED in adults but IED persisted outside the duration window in many (ADHD) or most (ODD, CD) cases. Measures of impulsive aggression severity were highest in those with IED+DBD but relatively low in those with DBD alone while measures of DBD severity were highest in those with DBD alone and in those with IED+DBD.

Conclusion

Despite the comorbidity of IED with the DBDs, IED can be separated from the DBDs over time and in terms of severity measures of IED and of DBD. Overall, impulsive aggression varies with IED while DBD behaviors vary with DBD. Based on this, clinicians should consider IED in their differential in the workup of impulsively aggressive children and adolescents.
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Metadata
Title
Comorbidity of disruptive behavior disorders and intermittent explosive disorder
Authors
Karam Radwan
Emil F. Coccaro
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Child and Adolescent Psychiatry and Mental Health / Issue 1/2020
Electronic ISSN: 1753-2000
DOI
https://doi.org/10.1186/s13034-020-00330-w

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