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Published in: BioPsychoSocial Medicine 1/2019

Open Access 01-12-2019 | Antidepressant Drugs | Review

Current management strategies for the pain of elderly patients with burning mouth syndrome: a critical review

Authors: Trang T. H. Tu, Miho Takenoshita, Hirofumi Matsuoka, Takeshi Watanabe, Takayuki Suga, Yuma Aota, Yoshihiro Abiko, Akira Toyofuku

Published in: BioPsychoSocial Medicine | Issue 1/2019

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Abstract

Burning Mouth Syndrome (BMS), a chronic intraoral burning sensation or dysesthesia without clinically evident causes, is one of the most common medically unexplained oral symptoms/syndromes. Even though the clinical features of BMS have been astonishingly common and consistent throughout the world for hundreds of years, BMS remains an enigma and has evolved to more intractable condition. In fact, there is a large and growing number of elderly BMS patients for whom the disease is accompanied by systemic diseases, in addition to aging physical change, which makes the diagnosis and treatment of BMS more difficult. Because the biggest barrier preventing us from finding the core pathophysiology and best therapy for BMS seems to be its heterogeneity, this syndrome remains challenging for clinicians. In this review, we discuss currently hopeful management strategies, including central neuromodulators (Tricyclic Antidepressants - TCAs, Serotonin, and Norepinephrine Reuptake Inhibitors - SNRIs, Selective Serotonin Reuptake Inhibitors - SSRIs, Clonazepam) and solutions for applying non-pharmacology approaches. Moreover, we also emphasize the important role of patient education and anxiety management to improve the patients’ quality of life. A combination of optimized medication with a short-term supportive psychotherapeutic approach might be a useful solution.
Literature
1.
go back to reference Merskey H, Bogduk N. Classification of Chronic Pain. 2nd ed. Seattle, WA: IASP Press;. Descriptions of chronic pain syndromes and definitions of pain terms;1994 p.74. Merskey H, Bogduk N. Classification of Chronic Pain. 2nd ed. Seattle, WA: IASP Press;. Descriptions of chronic pain syndromes and definitions of pain terms;1994 p.74.
3.
go back to reference Grushka M, Epstein JB, Gorsky M. Burning mouth syndrome. Am Fam Physician. 2002;65(4):615–20.PubMed Grushka M, Epstein JB, Gorsky M. Burning mouth syndrome. Am Fam Physician. 2002;65(4):615–20.PubMed
4.
go back to reference Forssell H, Jääskeläinen S, List T, Svensson P, Baad-Hansen L. An update on pathophysiological mechanisms related to idiopathic oro-facial pain conditions with implications for management. J Oral Rehabil. 2015;42(4):300–22.PubMedCrossRef Forssell H, Jääskeläinen S, List T, Svensson P, Baad-Hansen L. An update on pathophysiological mechanisms related to idiopathic oro-facial pain conditions with implications for management. J Oral Rehabil. 2015;42(4):300–22.PubMedCrossRef
5.
go back to reference Steele JC. The practical evaluation and management of patients with symptoms of a sore burning mouth. Clin Dermatol. 2016;34(4):449–57.PubMedCrossRef Steele JC. The practical evaluation and management of patients with symptoms of a sore burning mouth. Clin Dermatol. 2016;34(4):449–57.PubMedCrossRef
6.
go back to reference Patton LL, Siegel MA, Benoliel R, de Laat A. Management of burning mouth syndrome: systematic review and management recommendations. Oral Surg Oral Med Oral Pathol Oral Radiol Endo. 2007;103(suppl.39):S39.e1–S39.e13. Patton LL, Siegel MA, Benoliel R, de Laat A. Management of burning mouth syndrome: systematic review and management recommendations. Oral Surg Oral Med Oral Pathol Oral Radiol Endo. 2007;103(suppl.39):S39.e1–S39.e13.
9.
go back to reference Charleston L 4th. Burning mouth syndrome: a review of recent literature. Curr Pain Headache Rep. 2013;17(6):336.PubMedCrossRef Charleston L 4th. Burning mouth syndrome: a review of recent literature. Curr Pain Headache Rep. 2013;17(6):336.PubMedCrossRef
11.
go back to reference Moghadam-Kia S, Fazel N. A diagnostic and therapeutic approach to primary burning mouth syndrome. Clin Dermatol. 2017;35(5):453–60.PubMedCrossRef Moghadam-Kia S, Fazel N. A diagnostic and therapeutic approach to primary burning mouth syndrome. Clin Dermatol. 2017;35(5):453–60.PubMedCrossRef
12.
go back to reference Suga T, Watanabe T, Aota Y, Nagamine T, Toyofuku A. Burning mouth syndrome: the challenge of an aging population. Geriatr Gerontol Int 2018: Article in Press. Suga T, Watanabe T, Aota Y, Nagamine T, Toyofuku A. Burning mouth syndrome: the challenge of an aging population. Geriatr Gerontol Int 2018: Article in Press.
13.
go back to reference Breckons M, Shen J, Bunga J, Vale L, Study DJDEEP. Indirect and out-of-pocket costs of persistent orofacial pain. J Dent Res. 2018. Breckons M, Shen J, Bunga J, Vale L, Study DJDEEP. Indirect and out-of-pocket costs of persistent orofacial pain. J Dent Res. 2018.
14.
go back to reference Yap T, McCullough M. Oral medicine and the ageing population. Aust Dent J. 2015;60(Suppl 1):44–53.PubMedCrossRef Yap T, McCullough M. Oral medicine and the ageing population. Aust Dent J. 2015;60(Suppl 1):44–53.PubMedCrossRef
15.
go back to reference The International Classification of Headache Disorders, 3rd edition. Cephalalgia 2018,38(1):178. The International Classification of Headache Disorders, 3rd edition. Cephalalgia 2018,38(1):178.
16.
go back to reference Jääskeläinen SK. Pathophysiology of primary burning mouth syndrome. Clin Neurophysiol. 2012;123(1):71–7.PubMedCrossRef Jääskeläinen SK. Pathophysiology of primary burning mouth syndrome. Clin Neurophysiol. 2012;123(1):71–7.PubMedCrossRef
17.
go back to reference Kohorst JJ, Bruce AJ, Torgerson RR, Schenck LA, Davis MD. The prevalence of burning mouth syndrome: a population-based study. Br J Dermatol. 2015;172(6):1654–6.PubMedPubMedCentralCrossRef Kohorst JJ, Bruce AJ, Torgerson RR, Schenck LA, Davis MD. The prevalence of burning mouth syndrome: a population-based study. Br J Dermatol. 2015;172(6):1654–6.PubMedPubMedCentralCrossRef
18.
go back to reference Bergdahl M, Bergdahl J. Burning mouth syndrome: prevalence and associated factors. J Oral Pathol Med. 1999;28(8):350–4.PubMedCrossRef Bergdahl M, Bergdahl J. Burning mouth syndrome: prevalence and associated factors. J Oral Pathol Med. 1999;28(8):350–4.PubMedCrossRef
19.
20.
go back to reference Takenoshita M, Sato T, Kato Y, et al. Psychiatric diagnoses in patients with burning mouth syndrome and atypical odontalgia referred from psychiatric to dental facilities. Neuropsychiatr Dis Treat. 2010;6:699–705.PubMedPubMedCentral Takenoshita M, Sato T, Kato Y, et al. Psychiatric diagnoses in patients with burning mouth syndrome and atypical odontalgia referred from psychiatric to dental facilities. Neuropsychiatr Dis Treat. 2010;6:699–705.PubMedPubMedCentral
21.
go back to reference Tu TTH, Miura A, Shinohara Y, Mikuzuki L, Kawasaki K, Sugawara S, Suga T, Watanabe T, Watanabe M, Umezaki Y, Yoshikawa T, Motomura H, Takenoshita M, Toyofuku A. Evaluating burning mouth syndrome as a comorbidity of atypical Odontalgia: the impact on pain experiences. Pain Pract. 2017;18(5):580–6.PubMedCrossRef Tu TTH, Miura A, Shinohara Y, Mikuzuki L, Kawasaki K, Sugawara S, Suga T, Watanabe T, Watanabe M, Umezaki Y, Yoshikawa T, Motomura H, Takenoshita M, Toyofuku A. Evaluating burning mouth syndrome as a comorbidity of atypical Odontalgia: the impact on pain experiences. Pain Pract. 2017;18(5):580–6.PubMedCrossRef
22.
go back to reference Abetz LM, Savage NW. Burning mouth syndrome and psychological disorders. Aust Dent J. 2009;54(2):84–93.PubMedCrossRef Abetz LM, Savage NW. Burning mouth syndrome and psychological disorders. Aust Dent J. 2009;54(2):84–93.PubMedCrossRef
23.
go back to reference de Souza FT, Teixeira AL, Amaral TM, dos Santos TP, Abreu MH, Silva TA, Kummer A. Psychiatric disorders in burning mouth syndrome. J Psychosom Res. 2012;72(2):142–6.PubMedCrossRef de Souza FT, Teixeira AL, Amaral TM, dos Santos TP, Abreu MH, Silva TA, Kummer A. Psychiatric disorders in burning mouth syndrome. J Psychosom Res. 2012;72(2):142–6.PubMedCrossRef
24.
25.
go back to reference Leimola-Virtanen R, et al. Expression of estrogen receptor (ER) in oral mucosa and salivary glands. Maturitas. 2000;36:131–7.PubMedCrossRef Leimola-Virtanen R, et al. Expression of estrogen receptor (ER) in oral mucosa and salivary glands. Maturitas. 2000;36:131–7.PubMedCrossRef
26.
go back to reference Grushka M, et al. Taste dysfunction in burning mouth syndrome. Gerodontics. 1988;4:256–8.PubMed Grushka M, et al. Taste dysfunction in burning mouth syndrome. Gerodontics. 1988;4:256–8.PubMed
27.
go back to reference Jääskeläinen SK. Clinical neurophysiology and quantitative sensory testing in the investigation of orofacial pain and sensory function. J Orofac Pain. 2004;18(2):85–107.PubMed Jääskeläinen SK. Clinical neurophysiology and quantitative sensory testing in the investigation of orofacial pain and sensory function. J Orofac Pain. 2004;18(2):85–107.PubMed
28.
go back to reference Neblett R, Cohen H, Choi Y, Hartzell MM, Williams M, Mayer TG, Gatchel RJ. The central sensitization inventory (CSI): establishing clinically significant values for identifying central sensitivity syndromes in an outpatient chronic pain sample. J Pain. 2013;14(5):438–45.PubMedPubMedCentralCrossRef Neblett R, Cohen H, Choi Y, Hartzell MM, Williams M, Mayer TG, Gatchel RJ. The central sensitization inventory (CSI): establishing clinically significant values for identifying central sensitivity syndromes in an outpatient chronic pain sample. J Pain. 2013;14(5):438–45.PubMedPubMedCentralCrossRef
30.
go back to reference Jääskeläinen SK. Is burning mouth syndrome a neuropathic pain condition? Pain. 2018;159(3):610–3.PubMed Jääskeläinen SK. Is burning mouth syndrome a neuropathic pain condition? Pain. 2018;159(3):610–3.PubMed
32.
go back to reference Umezaki Y, Miura A, Shinohara Y, Mikuzuki L, Sugawara S, Kawasaki K, Toyofuku A. Clinical characteristics and course of oral somatic delusions: a retrospective chart review of 606 cases in 5 years. Neuropsychiatr Dis Treat. 2018;14:2057–65.PubMedPubMedCentralCrossRef Umezaki Y, Miura A, Shinohara Y, Mikuzuki L, Sugawara S, Kawasaki K, Toyofuku A. Clinical characteristics and course of oral somatic delusions: a retrospective chart review of 606 cases in 5 years. Neuropsychiatr Dis Treat. 2018;14:2057–65.PubMedPubMedCentralCrossRef
33.
34.
go back to reference Khan SA, Keaser ML, Meiller TF, Seminowicz DA. Altered structure and function in the hippocampus and medial prefrontal cortex in patients with burning mouth syndrome. Pain. 2014;155(8):1472–80.PubMedCrossRef Khan SA, Keaser ML, Meiller TF, Seminowicz DA. Altered structure and function in the hippocampus and medial prefrontal cortex in patients with burning mouth syndrome. Pain. 2014;155(8):1472–80.PubMedCrossRef
35.
go back to reference Shinozaki T, Imamura Y, Kohashi R, Dezawa K, Nakaya Y, Sato Y, Watanabe K, Morimoto Y, Shizukuishi T, Abe O, Haji T, Tabei K, Taira M. Spatial and temporal brain responses to noxious heat thermal stimuli in burning mouth syndrome. J Dent Res. 2016;95(10):1138–46.PubMedCrossRef Shinozaki T, Imamura Y, Kohashi R, Dezawa K, Nakaya Y, Sato Y, Watanabe K, Morimoto Y, Shizukuishi T, Abe O, Haji T, Tabei K, Taira M. Spatial and temporal brain responses to noxious heat thermal stimuli in burning mouth syndrome. J Dent Res. 2016;95(10):1138–46.PubMedCrossRef
36.
go back to reference Yoshino A, Okamoto Y, Doi M, Okada G, Takamura M, Ichikawa N, Yamawaki S. Functional alterations of postcentral gyrus modulated by angry facial expressions during intraoral tactile stimuli in patients with burning mouth syndrome: a functional magnetic resonance imaging Study. Front Psychiatry. 2017;6(8):224.CrossRef Yoshino A, Okamoto Y, Doi M, Okada G, Takamura M, Ichikawa N, Yamawaki S. Functional alterations of postcentral gyrus modulated by angry facial expressions during intraoral tactile stimuli in patients with burning mouth syndrome: a functional magnetic resonance imaging Study. Front Psychiatry. 2017;6(8):224.CrossRef
37.
go back to reference Wada A, Shizukuishi T, Kikuta J, Yamada H, Watanabe Y, Imamura Y, Shinozaki T, Dezawa K, Haradome H, Abe O. Altered structural connectivity of pain-related brain network in burning mouth syndrome-investigation by graph analysis of probabilistic tractography. Neuroradiology. 2017;59(5):525–32.PubMedCrossRef Wada A, Shizukuishi T, Kikuta J, Yamada H, Watanabe Y, Imamura Y, Shinozaki T, Dezawa K, Haradome H, Abe O. Altered structural connectivity of pain-related brain network in burning mouth syndrome-investigation by graph analysis of probabilistic tractography. Neuroradiology. 2017;59(5):525–32.PubMedCrossRef
38.
go back to reference Katagiri A, Sato Y, Umezaki Y, Sato T, Watanabe M, Takenoshita M, Yoshikawa T, Toyofuku A. Burning mouth Syndrome in an aged patient with Alzheimer's Disease : A case report. Jpn J Psychosom Dent. 2011;26(1):36–40 (article in Japanese). Katagiri A, Sato Y, Umezaki Y, Sato T, Watanabe M, Takenoshita M, Yoshikawa T, Toyofuku A. Burning mouth Syndrome in an aged patient with Alzheimer's Disease : A case report. Jpn J Psychosom Dent. 2011;26(1):36–40 (article in Japanese).
39.
go back to reference Feller L, Fourie J, Bouckaert M, Khammissa RAG, Ballyram R, Lemmer J. Burning mouth syndrome: Aetiopathogenesis and principles of management. Pain Res Manag. 2017:1926269. Feller L, Fourie J, Bouckaert M, Khammissa RAG, Ballyram R, Lemmer J. Burning mouth syndrome: Aetiopathogenesis and principles of management. Pain Res Manag. 2017:1926269.
40.
go back to reference Tait RC, Ferguson M, Herndon CM. Chronic orofacial pain: burning mouth syndrome and other neuropathic disorders. J Pain Manag Med 2017;3(1). pii:120. Tait RC, Ferguson M, Herndon CM. Chronic orofacial pain: burning mouth syndrome and other neuropathic disorders. J Pain Manag Med 2017;3(1). pii:120.
41.
go back to reference Mignogna MD, Fedele S, Lo Russo L, Leuci S, Lo Muzio L. The diagnosis of burning mouth syndrome represents a challenge for clinicians. J Orofac Pain. 2005;19(2):168–73.PubMed Mignogna MD, Fedele S, Lo Russo L, Leuci S, Lo Muzio L. The diagnosis of burning mouth syndrome represents a challenge for clinicians. J Orofac Pain. 2005;19(2):168–73.PubMed
42.
go back to reference Häggman-Henrikson B, Alstergren P, Davidson T, Högestätt ED, Östlund P, Tranaeus S, Vitols S, List T. Pharmacological treatment of oro-facial pain - health technology assessment including a systematic review with network meta- analysis. J Oral Rehabil. 2017;44(10):800–26.PubMedCrossRef Häggman-Henrikson B, Alstergren P, Davidson T, Högestätt ED, Östlund P, Tranaeus S, Vitols S, List T. Pharmacological treatment of oro-facial pain - health technology assessment including a systematic review with network meta- analysis. J Oral Rehabil. 2017;44(10):800–26.PubMedCrossRef
43.
go back to reference Fischoff D, Spivakovsky S. Are pharmacological treatments for oro-facial pain effective? Evid Based Dent. 2018 Mar 23;19(1):28–9.PubMedCrossRef Fischoff D, Spivakovsky S. Are pharmacological treatments for oro-facial pain effective? Evid Based Dent. 2018 Mar 23;19(1):28–9.PubMedCrossRef
45.
go back to reference McMillan R, Forssell H, Buchanan JA, Glenny AM, Weldon JC, Zakrzewska JM. Interventions for treating burning mouth syndrome. Cochrane Database Syst Rev. 2016;11:CD002779.PubMed McMillan R, Forssell H, Buchanan JA, Glenny AM, Weldon JC, Zakrzewska JM. Interventions for treating burning mouth syndrome. Cochrane Database Syst Rev. 2016;11:CD002779.PubMed
46.
go back to reference Fischoff DK, Spivakovsky S. Little evidence to support or refute interventions for the management of burning mouth syndrome. Evid Based Dent. 2017;18(2):57–8.PubMedCrossRef Fischoff DK, Spivakovsky S. Little evidence to support or refute interventions for the management of burning mouth syndrome. Evid Based Dent. 2017;18(2):57–8.PubMedCrossRef
48.
go back to reference Toye F. Not everything that can be counted counts and not everything that counts can be counted' (attributed to Albert Einstein). Br J Pain. 2015;9(1):7.PubMedPubMedCentralCrossRef Toye F. Not everything that can be counted counts and not everything that counts can be counted' (attributed to Albert Einstein). Br J Pain. 2015;9(1):7.PubMedPubMedCentralCrossRef
50.
51.
go back to reference Peciña M, Bohnert AS, Sikora M, Avery ET, Langenecker SA, Mickey BJ, Zubieta JK. Association between placebo-activated neural systems and antidepressant responses: neurochemistry of placebo effects in major depression. JAMA Psychiatry. 2015;72(11):1087–94.PubMedPubMedCentralCrossRef Peciña M, Bohnert AS, Sikora M, Avery ET, Langenecker SA, Mickey BJ, Zubieta JK. Association between placebo-activated neural systems and antidepressant responses: neurochemistry of placebo effects in major depression. JAMA Psychiatry. 2015;72(11):1087–94.PubMedPubMedCentralCrossRef
52.
go back to reference de Souza IF, Mármora BC, Rados PV, Visioli F. Treatment modalities for burning mouth syndrome: a systematic review. Clin Oral Investig. 2018;22(5):1893–905.PubMedCrossRef de Souza IF, Mármora BC, Rados PV, Visioli F. Treatment modalities for burning mouth syndrome: a systematic review. Clin Oral Investig. 2018;22(5):1893–905.PubMedCrossRef
53.
go back to reference Toyofuku A. From psychosomatic dentistry to brain dentistry. Kokubyo Gakkai Zasshi 2007;74(3):161–168. (Article in Japanese). Toyofuku A. From psychosomatic dentistry to brain dentistry. Kokubyo Gakkai Zasshi 2007;74(3):161–168. (Article in Japanese).
54.
go back to reference Fenelon M, Quinque E, Arrive E, Catros S, Fricain JC. Pain-relieving effects of clonazepam and amitriptyline in burning mouth syndrome: a retrospective study. Int J Oral Maxillofac Surg. 2017;46(11):1505–11.PubMedCrossRef Fenelon M, Quinque E, Arrive E, Catros S, Fricain JC. Pain-relieving effects of clonazepam and amitriptyline in burning mouth syndrome: a retrospective study. Int J Oral Maxillofac Surg. 2017;46(11):1505–11.PubMedCrossRef
55.
go back to reference Kawasaki K, Nagamine T, Watanabe T, Suga T, Tu TTH, Sugawara S, Mikuzuki L, Miura A, Shinohara Y, Yoshikawa T, Takenoshita M, Toyofuku A. An increase in salivary flow with amitriptyline may indicate treatment resistance in burning mouth syndrome. Asia Pac Psychiatry. 2018;25:e12315.CrossRef Kawasaki K, Nagamine T, Watanabe T, Suga T, Tu TTH, Sugawara S, Mikuzuki L, Miura A, Shinohara Y, Yoshikawa T, Takenoshita M, Toyofuku A. An increase in salivary flow with amitriptyline may indicate treatment resistance in burning mouth syndrome. Asia Pac Psychiatry. 2018;25:e12315.CrossRef
56.
go back to reference Takeshi Watanabe, Kaoru Kawasaki, Trang T.H Tu, Takayuki Suga, Shiori Sugawara, Lou Mikuzuki, Anna Miura, Yukiko Shinohara, Tatsuya Yoshikawa, Miho Takenoshita, Akira Toyofuku, Takahiko Nagamine, The QTc shortening with amitriptyline may indicate treatment resistance in chronic nonorganic orofacial pain. Clinical Neuropsychopharmacology and Therapeutics, Released April 10, 2018, Online ISSN 1884–8826, Print ISSN. Takeshi Watanabe, Kaoru Kawasaki, Trang T.H Tu, Takayuki Suga, Shiori Sugawara, Lou Mikuzuki, Anna Miura, Yukiko Shinohara, Tatsuya Yoshikawa, Miho Takenoshita, Akira Toyofuku, Takahiko Nagamine, The QTc shortening with amitriptyline may indicate treatment resistance in chronic nonorganic orofacial pain. Clinical Neuropsychopharmacology and Therapeutics, Released April 10, 2018, Online ISSN 1884–8826, Print ISSN.
57.
go back to reference Toyofuku A. Efficacy of milnacipran for glossodynia patients. Int J Psychiatry Clin Pract. 2003;7(Suppl 1):23–4.PubMedCrossRef Toyofuku A. Efficacy of milnacipran for glossodynia patients. Int J Psychiatry Clin Pract. 2003;7(Suppl 1):23–4.PubMedCrossRef
58.
go back to reference Kato Y, Sato T, Katagiri A, Umezaki Y, Takenoshita M, Yoshikawa T, Sato Y, Toyofuku A. Milnacipran dose-effect study in patients with burning mouth syndrome. Clin Neuropharmacol. 2011;34(4):166–9.PubMedCrossRef Kato Y, Sato T, Katagiri A, Umezaki Y, Takenoshita M, Yoshikawa T, Sato Y, Toyofuku A. Milnacipran dose-effect study in patients with burning mouth syndrome. Clin Neuropharmacol. 2011;34(4):166–9.PubMedCrossRef
59.
go back to reference Mitsikostas DD, Ljubisavljevic S, Deligianni CI. Refractory burning mouth syndrome: clinical and paraclinical evaluation, comorbiities. treatment and outcome J Headache Pain. 2017;18(1):40. Mitsikostas DD, Ljubisavljevic S, Deligianni CI. Refractory burning mouth syndrome: clinical and paraclinical evaluation, comorbiities. treatment and outcome J Headache Pain. 2017;18(1):40.
60.
go back to reference Nagamine T. Responsibility of the doctor who prescribes serotonin and noradrenaline reuptake inhibitors for patients with chronic musculoskeletal pain. Psychiatry Clin Neurosci. 2018;72(1):45–6.PubMedCrossRef Nagamine T. Responsibility of the doctor who prescribes serotonin and noradrenaline reuptake inhibitors for patients with chronic musculoskeletal pain. Psychiatry Clin Neurosci. 2018;72(1):45–6.PubMedCrossRef
61.
go back to reference Riediger C, Schuster T, Barlinn K, Maier S, Weitz J, Siepmann T. Adverse effects of antidepressants for chronic pain: a systematic review and Meta-analysis. Front Neurol. 2017;8:307.PubMedPubMedCentralCrossRef Riediger C, Schuster T, Barlinn K, Maier S, Weitz J, Siepmann T. Adverse effects of antidepressants for chronic pain: a systematic review and Meta-analysis. Front Neurol. 2017;8:307.PubMedPubMedCentralCrossRef
62.
go back to reference Drossman DA, Tack J, Ford AC, Szigethy E, Törnblom H, Van Oudenhove L. Neuromodulators for functional gastrointestinal disorders (disorders of gut−brain interaction): a Rome Foundation working team report. Gastroenterology 2018;154:1140–1171. Drossman DA, Tack J, Ford AC, Szigethy E, Törnblom H, Van Oudenhove L. Neuromodulators for functional gastrointestinal disorders (disorders of gut−brain interaction): a Rome Foundation working team report. Gastroenterology 2018;154:1140–1171.
63.
go back to reference Takenoshita M, Motomura H, Toyofuku A. Low-dose aripiprazole augmentation in amitriptyline-resistant burning mouth syndrome: results from two cases. Pain Med. 2017;18(4):814–5.PubMedPubMedCentral Takenoshita M, Motomura H, Toyofuku A. Low-dose aripiprazole augmentation in amitriptyline-resistant burning mouth syndrome: results from two cases. Pain Med. 2017;18(4):814–5.PubMedPubMedCentral
64.
65.
go back to reference Jimenez XF, Sundararajan T, Covington EC. A systematic review of atypical antipsychotics in chronic pain management: olanzapine demonstrates potential in central sensitization, fibromyalgia, and headache/migraine. Clin J Pain. 2018;34(6):585–91.PubMedCrossRef Jimenez XF, Sundararajan T, Covington EC. A systematic review of atypical antipsychotics in chronic pain management: olanzapine demonstrates potential in central sensitization, fibromyalgia, and headache/migraine. Clin J Pain. 2018;34(6):585–91.PubMedCrossRef
66.
go back to reference Heckmann SM, Kirchner E, Grushka M, Wichmann MG. Hummel T. A double-blind study on clonazepam in patients with burning mouth syndrome. Laryngoscope. 2012;122(4):813–6.PubMedCrossRef Heckmann SM, Kirchner E, Grushka M, Wichmann MG. Hummel T. A double-blind study on clonazepam in patients with burning mouth syndrome. Laryngoscope. 2012;122(4):813–6.PubMedCrossRef
67.
go back to reference Kuten-Shorrer M, Treister NS, Stock S, Kelley JM, Ji YD, Woo SB, Lerman MA, Palmason S, Sonis ST, Villa A. Topical clonazepam solution for the Management of Burning Mouth Syndrome: a retrospective Study. J Oral Facial Pain Headache. 2017;31(3):257–63.PubMedCrossRef Kuten-Shorrer M, Treister NS, Stock S, Kelley JM, Ji YD, Woo SB, Lerman MA, Palmason S, Sonis ST, Villa A. Topical clonazepam solution for the Management of Burning Mouth Syndrome: a retrospective Study. J Oral Facial Pain Headache. 2017;31(3):257–63.PubMedCrossRef
68.
go back to reference Goodman CW, Brett AS. Gabapentin and Pregabalin for pain - is increased prescribing a cause for concern? N Engl J Med. 2017;377(5):411–4.PubMedCrossRef Goodman CW, Brett AS. Gabapentin and Pregabalin for pain - is increased prescribing a cause for concern? N Engl J Med. 2017;377(5):411–4.PubMedCrossRef
69.
go back to reference Bergdahl J, Anneroth G, Perris H. Cognitive therapy in the treatment of patients with resistant burning mouth syndrome: a controlled study. J Oral Pathol Med. 1995;24(5):213–5.PubMedCrossRef Bergdahl J, Anneroth G, Perris H. Cognitive therapy in the treatment of patients with resistant burning mouth syndrome: a controlled study. J Oral Pathol Med. 1995;24(5):213–5.PubMedCrossRef
70.
go back to reference Femiano F, Gombos F, Scully C. Burning mouth syndrome: open trial of psychotherapy alone, medication with alpha-lipoic acid (thioctic acid). and combination therapy Med Oral. 2004;9(1):8–13. Femiano F, Gombos F, Scully C. Burning mouth syndrome: open trial of psychotherapy alone, medication with alpha-lipoic acid (thioctic acid). and combination therapy Med Oral. 2004;9(1):8–13.
71.
go back to reference Komiyama O, Nishimura H, Makiyama Y, et al. Group cognitive-behavioral intervention for patients with burning mouth syndrome. J Oral Sci. 2013;55(1):17–22.PubMedCrossRef Komiyama O, Nishimura H, Makiyama Y, et al. Group cognitive-behavioral intervention for patients with burning mouth syndrome. J Oral Sci. 2013;55(1):17–22.PubMedCrossRef
72.
go back to reference Wergeland GJ, Fjermestad KW, Marin CE, et al. An effectiveness study of individual vs. group cognitive behavioral therapy for anxiety disorders in youth. Behav Res Ther. 2014;57:1–12.PubMedCrossRef Wergeland GJ, Fjermestad KW, Marin CE, et al. An effectiveness study of individual vs. group cognitive behavioral therapy for anxiety disorders in youth. Behav Res Ther. 2014;57:1–12.PubMedCrossRef
73.
go back to reference Matsuoka H, Himachi M, Furukawa H, et al. Cognitive profile of patients with burning mouth syndrome in the Japanese population. Odontology. 2010;98(2):160–4.PubMedCrossRef Matsuoka H, Himachi M, Furukawa H, et al. Cognitive profile of patients with burning mouth syndrome in the Japanese population. Odontology. 2010;98(2):160–4.PubMedCrossRef
74.
go back to reference Matsuoka H, Chiba I, Sakano Y, Toyofuku A, Abiko Y. Cognitive behavioral therapy for psychosomatic problems in dental settings. Biopsychosoc Med. 2017;13(11):18.CrossRef Matsuoka H, Chiba I, Sakano Y, Toyofuku A, Abiko Y. Cognitive behavioral therapy for psychosomatic problems in dental settings. Biopsychosoc Med. 2017;13(11):18.CrossRef
75.
go back to reference Brailo V, Firić M, Vučićević Boras V, Andabak Rogulj A, Krstevski I, Alajbeg I. Impact of reassurance on pain perception in patients with primary burning mouth syndrome. Oral Dis. 2016;22(6):512–6.PubMedCrossRef Brailo V, Firić M, Vučićević Boras V, Andabak Rogulj A, Krstevski I, Alajbeg I. Impact of reassurance on pain perception in patients with primary burning mouth syndrome. Oral Dis. 2016;22(6):512–6.PubMedCrossRef
76.
go back to reference Lopez-Jornet P, Lucero-Berdugo M, Castillo-Felipe C, Zamora Lavella C, Ferrandez-Pujante A, Pons-Fuster A. Assessment of self-reported sleep disturbance and psychological status in patients with burning mouth syndrome. J Eur Acad Dermatol Venereol. 2015;29(7):1285–90.PubMedCrossRef Lopez-Jornet P, Lucero-Berdugo M, Castillo-Felipe C, Zamora Lavella C, Ferrandez-Pujante A, Pons-Fuster A. Assessment of self-reported sleep disturbance and psychological status in patients with burning mouth syndrome. J Eur Acad Dermatol Venereol. 2015;29(7):1285–90.PubMedCrossRef
77.
go back to reference Cheatle MD, Foster S, Pinkett A, Lesneski M, Qu D, Dhingra L. Assessing and managing sleep disturbance in patients with chronic pain. Sleep Med Clin. 2016;11(4):531–41.PubMedCrossRef Cheatle MD, Foster S, Pinkett A, Lesneski M, Qu D, Dhingra L. Assessing and managing sleep disturbance in patients with chronic pain. Sleep Med Clin. 2016;11(4):531–41.PubMedCrossRef
78.
go back to reference Lami MJ, Martínez MP, Miró E, et al. Efficacy of combined cognitive- behavioral therapy for insomnia and pain in patients with fibromyalgia: a randomized controlled trial. Cogn Ther Res. 2018;42(1):63–79.CrossRef Lami MJ, Martínez MP, Miró E, et al. Efficacy of combined cognitive- behavioral therapy for insomnia and pain in patients with fibromyalgia: a randomized controlled trial. Cogn Ther Res. 2018;42(1):63–79.CrossRef
79.
go back to reference Bulloch AG, Patten SB. Non-adherence with psychotropic medications in the general population. Soc Psychiatry Psychiatr Epidemiol. 2010;45(1):47–56.PubMedCrossRef Bulloch AG, Patten SB. Non-adherence with psychotropic medications in the general population. Soc Psychiatry Psychiatr Epidemiol. 2010;45(1):47–56.PubMedCrossRef
80.
go back to reference Yamazaki Y, Hata H, Kitamori S, Onodera M, Kitagawa Y. An open-label, noncomparative, dose escalation pilot study of the effect of paroxetine in treatment of burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(1):e6–11.PubMedCrossRef Yamazaki Y, Hata H, Kitamori S, Onodera M, Kitagawa Y. An open-label, noncomparative, dose escalation pilot study of the effect of paroxetine in treatment of burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(1):e6–11.PubMedCrossRef
81.
go back to reference Palacio A, Garay D, Langer B, Taylor J, Wood BA, Tamariz L. Motivational interviewing improves medication adherence: a systematic review and Meta- analysis. J Gen Intern Med. 2016;31(8):929–40.PubMedPubMedCentralCrossRef Palacio A, Garay D, Langer B, Taylor J, Wood BA, Tamariz L. Motivational interviewing improves medication adherence: a systematic review and Meta- analysis. J Gen Intern Med. 2016;31(8):929–40.PubMedPubMedCentralCrossRef
82.
go back to reference Umezaki Y, Badran BW, DeVries WH, Moss J, Gonzales T, George MS. The efficacy of daily prefrontal repetitive transcranial magnetic stimulation (rTMS) for burning mouth syndrome (BMS): a randomized controlled single-blind Study. Brain Stimul. 2016;9(2):234–42.PubMedCrossRef Umezaki Y, Badran BW, DeVries WH, Moss J, Gonzales T, George MS. The efficacy of daily prefrontal repetitive transcranial magnetic stimulation (rTMS) for burning mouth syndrome (BMS): a randomized controlled single-blind Study. Brain Stimul. 2016;9(2):234–42.PubMedCrossRef
83.
go back to reference Umezaki Y, Badran BW, Gonzales TS, George MS. Daily left prefrontal repetitive transcranial magnetic stimulation for medication-resistant burning mouth syndrome. Int J Oral Maxillofac Surg. 2015;44(8):1048–51.PubMedCrossRef Umezaki Y, Badran BW, Gonzales TS, George MS. Daily left prefrontal repetitive transcranial magnetic stimulation for medication-resistant burning mouth syndrome. Int J Oral Maxillofac Surg. 2015;44(8):1048–51.PubMedCrossRef
84.
go back to reference Suda S, Takagai S, Inoshima-Takahashi K, Sugihara G, Mori N, Takei N. Electroconvulsive therapy for burning mouth syndrome. Acta Psychiatr Scand. 2008;118(6):503–4.PubMedCrossRef Suda S, Takagai S, Inoshima-Takahashi K, Sugihara G, Mori N, Takei N. Electroconvulsive therapy for burning mouth syndrome. Acta Psychiatr Scand. 2008;118(6):503–4.PubMedCrossRef
85.
go back to reference McGirr A, Davis L, Vila-Rodriguez F. Idiopathic burning mouth syndrome: a common treatment-refractory somatoform condition responsive to ECT. Psychiatry Res. 2014;216(1):158–9.PubMedCrossRef McGirr A, Davis L, Vila-Rodriguez F. Idiopathic burning mouth syndrome: a common treatment-refractory somatoform condition responsive to ECT. Psychiatry Res. 2014;216(1):158–9.PubMedCrossRef
86.
go back to reference Li BY, Tang HD, Qiao Y, Chen SD. Mental training for cognitive improvement in elderly people: what have we learned from clinical and neurophysiologic studies? Curr Alzheimer Res. 2015;12(6):543–52.PubMedCrossRef Li BY, Tang HD, Qiao Y, Chen SD. Mental training for cognitive improvement in elderly people: what have we learned from clinical and neurophysiologic studies? Curr Alzheimer Res. 2015;12(6):543–52.PubMedCrossRef
87.
go back to reference LeBlanc A, Herrin J, Williams MD, Inselman JW, Branda ME, Shah ND, Heim EM, Dick SR, Linzer M, Boehm DH, Dall-Winther KM, Matthews MR, Yost KJ, Shepel KK, Montori VM. Shared decision making for antidepressants in primary care: a cluster randomized trial. JAMA Intern Med. 2015;175(11):1761–70.PubMedPubMedCentralCrossRef LeBlanc A, Herrin J, Williams MD, Inselman JW, Branda ME, Shah ND, Heim EM, Dick SR, Linzer M, Boehm DH, Dall-Winther KM, Matthews MR, Yost KJ, Shepel KK, Montori VM. Shared decision making for antidepressants in primary care: a cluster randomized trial. JAMA Intern Med. 2015;175(11):1761–70.PubMedPubMedCentralCrossRef
88.
go back to reference Van Damme S, Becker S, Van Der Linden D. Tired of pain? Toward a better understanding of fatigue in chronic pain. Pain. 2018;159:7–10.PubMedCrossRef Van Damme S, Becker S, Van Der Linden D. Tired of pain? Toward a better understanding of fatigue in chronic pain. Pain. 2018;159:7–10.PubMedCrossRef
89.
go back to reference Solberg LI, Crain AL, Rubenstein L, Unützer J, Whitebird RR, Beck A. How much shared decision making occurs in usual primary care of depression? J Am Board Fam Med. 2014;27(2):199–208.PubMedCrossRef Solberg LI, Crain AL, Rubenstein L, Unützer J, Whitebird RR, Beck A. How much shared decision making occurs in usual primary care of depression? J Am Board Fam Med. 2014;27(2):199–208.PubMedCrossRef
Metadata
Title
Current management strategies for the pain of elderly patients with burning mouth syndrome: a critical review
Authors
Trang T. H. Tu
Miho Takenoshita
Hirofumi Matsuoka
Takeshi Watanabe
Takayuki Suga
Yuma Aota
Yoshihiro Abiko
Akira Toyofuku
Publication date
01-12-2019
Publisher
BioMed Central
Published in
BioPsychoSocial Medicine / Issue 1/2019
Electronic ISSN: 1751-0759
DOI
https://doi.org/10.1186/s13030-019-0142-7

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