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Open Access 01-12-2017 | Review

Thalassemias in South Asia: clinical lessons learnt from Bangladesh

Authors: Mohammad Sorowar Hossain, Enayetur Raheem, Tanvira Afroze Sultana, Shameema Ferdous, Nusrat Nahar, Sazia Islam, Mohammad Arifuzzaman, Mohammad Abdur Razzaque, Rabiul Alam, Sonia Aziz, Hazera Khatun, Abdur Rahim, Manzur Morshed

Published in: Orphanet Journal of Rare Diseases | Issue 1/2017

Abstract

Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the coming decades in South Asia. Despite the fact that Bangladesh lies in the world’s thalassemia belt, the information on different aspects (epidemiology, clinical course, mortality, complications and treatment outcomes) of thalassemias is lacking. In this comprehensive review, the aim is to to depict the epidemiological aspects of thalassemias, mutation profile and current treatment and management practices in the country by sharing the experience of dealing with 1178 cases over 2009–2014 time periods in a specialized thalassemia treatment centre. We have also discussed the preventative strategies of thalassemias from the context of Bangladesh which could be effective for other developing countries.

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Title: Thalassemias in South Asia: clinical lessons learnt from Bangladesh
Authors: Mohammad Sorowar Hossain
Enayetur Raheem
Tanvira Afroze Sultana
Shameema Ferdous
Nusrat Nahar
Sazia Islam
Mohammad Arifuzzaman
Mohammad Abdur Razzaque
Rabiul Alam
Sonia Aziz
Hazera Khatun
Abdur Rahim
Manzur Morshed
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Orphanet Journal of Rare Diseases / Issue 1/2017
Electronic ISSN: 1750-1172
DOI: https://doi.org/10.1186/s13023-017-0643-z

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Thalassemias in South Asia: clinical lessons learnt from Bangladesh

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