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Published in: Chinese Medicine 1/2019

Open Access 01-12-2019 | Pneumonia | Review

Application of metabolomics in viral pneumonia treatment with traditional Chinese medicine

Authors: Lili Lin, Hua Yan, Jiabin Chen, Huihui Xie, Linxiu Peng, Tong Xie, Xia Zhao, Shouchuan Wang, Jinjun Shan

Published in: Chinese Medicine | Issue 1/2019

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Abstract

Nowadays, traditional Chinese medicines (TCMs) have been reported to provide reliable therapies for viral pneumonia, but the therapeutic mechanism remains unknown. As a systemic approach, metabolomics provides an opportunity to clarify the action mechanism of TCMs, TCM syndromes or after TCM treatment. This review aims to provide the metabolomics evidence available on TCM-based therapeutic measures against viral pneumonia. Metabolomics has been gradually applied to the efficacy evaluation of TCMs in treatment of viral pneumonia and the metabolomics analysis exhibits a systemic metabolic shift in lipid, amino acids, and energy metabolism. Currently, most studies of TCM in treatment of viral pneumonia are untargeted metabolomics and further validations on targeted metabolomics should be carried out together with molecular biology technologies.
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Metadata
Title
Application of metabolomics in viral pneumonia treatment with traditional Chinese medicine
Authors
Lili Lin
Hua Yan
Jiabin Chen
Huihui Xie
Linxiu Peng
Tong Xie
Xia Zhao
Shouchuan Wang
Jinjun Shan
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Pneumonia
Published in
Chinese Medicine / Issue 1/2019
Electronic ISSN: 1749-8546
DOI
https://doi.org/10.1186/s13020-019-0229-x

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