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Chinese Medicine
Published in: Chinese Medicine 1/2017

Open Access 01-12-2017 | Review

Anti-tumor effects of the American cockroach, Periplaneta americana

Authors: Yanan Zhao, Ailin Yang, Pengfei Tu, Zhongdong Hu

Published in: Chinese Medicine | Issue 1/2017

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Abstract

Since the incidence of cancer has been on the rise due to increasing exposure to various carcinogenic factors in recent years, cancer has gradually become the first killer to the health of human beings. A growing attention has been paid to anti-cancer effects of traditional Chinese medicine (TCM) with low toxicity and good efficacy. As a kind of TCM, Periplaneta americana (P. americana) has a good effect on clinical application, and its anti-tumor effects has been increasingly well studied. In this review, the research progress on the anti-tumor effects of P. americana was summarized. The main mechanisms of its anti-tumor effects include suppression of tumor cell growth, induction of cell cycle arrest and tumor cell apoptosis, inhibition of angiogenesis, enhancement of immunity, and reversal of tumor drug resistance. This review aims to provide an overview of the research on anti-tumor effects of P. americana and aids in its further application as an anti-tumor drug.
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Metadata
Title
Anti-tumor effects of the American cockroach, Periplaneta americana
Authors
Yanan Zhao
Ailin Yang
Pengfei Tu
Zhongdong Hu
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Chinese Medicine / Issue 1/2017
Electronic ISSN: 1749-8546
DOI
https://doi.org/10.1186/s13020-017-0149-6

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