Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Journal of Cardiothoracic Surgery
Published in: Journal of Cardiothoracic Surgery 1/2024

Open Access 01-12-2024 | Esophagus Resection | Research

Similar survival after endoscopic submucosal dissection and esophagectomy in early esophageal cancer and synchronous or metachronous head and neck cancer

Authors: Ruei-Ti Ke, Yu-Hsin Hsiao, Wei-Chen Tai, Shau-Hsuan Li, Chih-Chien Yao, Kai-Hao Chuang, Hsing-Hua Lai, Yu Chen, Li-Chun Chen, Hung-I Lu, Yen-Hao Chen, Chien-Ming Lo

Published in: Journal of Cardiothoracic Surgery | Issue 1/2024

Login to get access

Abstract

Background

Early-stage esophageal cancer is treated using endoscopic submucosal dissection and esophagectomy. Field cancerization in patients with early-stage esophageal cancer affects treatment outcomes and causes synchronous or metachronous head and neck cancers. We hypothesized that esophagectomy could provide better overall and relapse-free survivals in patients with esophageal cancer and synchronous or metachronous head and neck cancer.

Methods

We retrospectively identified patients with early esophageal squamous cell carcinoma and synchronous or metachronous head and neck cancers. We separated the patients into endoscopic submucosal dissection and esophagectomy groups to compare overall and relapse-free survivals.

Results

The study included 106 patients, 25 of whom underwent endoscopic submucosal dissection and 81 underwent esophagectomy. Overall and relapse-free survivals did not show significant differences between the two groups for both synchronous and metachronous head and neck cancers.

Conclusions

Endoscopic submucosal dissection could provide similar overall and relapse-free survivals in patients with esophageal cancer and synchronous or metachronous head and neck cancer.
Literature
1.
Huang B, Xu MC, Pennathur A, Li Z, Liu Z, Wu Q, et al. Endoscopic resection with adjuvant treatment versus esophagectomy for early-stage esophageal cancer. Surg Endosc. 2022;36:1868–75.CrossRefPubMed
2.
Le Page PA, Velu PP, Penman ID, Couper GW, Paterson-Brown S, Lamb PJ. Surgical and endoscopic management of high grade dysplasia and early oesophageal adenocarcinoma. Surgeon. 2016;14:315–21.CrossRefPubMed
3.
Min YW, Lee H, Song BG, Min BH, Kim HK, Choi YS, et al. Comparison of endoscopic submucosal dissection and surgery for superficial esophageal squamous cell carcinoma: a propensity score-matched analysis. Gastrointest Endosc. 2018;88:624–33.CrossRefPubMed
4.
Wang W, Chen D, Sang Y, Chen C, Zhang Y, Mao Y, et al. Endoscopic resection versus esophagectomy for patients with small-sized T1N0 esophageal cancer: a propensity-matched study. Clin Res Hepatol Gastroenterol. 2021;45:101543.CrossRefPubMed
5.
Zhang Y, Ding H, Chen T, Zhang X, Chen WF, Li Q, et al. Outcomes of endoscopic submucosal dissection vs esophagectomy for T1 esophageal squamous cell carcinoma in a real-world cohort. Clin Gastroenterol Hepatol. 2019;17:73–81. e3.CrossRefPubMed
6.
Chen SC, Teng CJ, Hu YW, Yeh CM, Hung MH, Hu LY, et al. Secondary primary malignancy risk among patients with esophageal cancer in Taiwan: a nationwide population-based study. PLoS ONE. 2015;10:e0116384.CrossRefPubMedPubMedCentral
7.
Ishihara R, Arima M, Iizuka T, Oyama T, Katada C, Kato M, et al. Endoscopic submucosal dissection/endoscopic mucosal resection guidelines for esophageal cancer. Dig Endoscopy. 2020;32:452–93.CrossRef
8.
Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer. 1953;6:963–8.CrossRefPubMed
9.
D’Journo XB, Fourdrain A. Oesophagectomy within 30 days after noncurative endoscopic resection for oesophageal cancer: are we able to follow this ‘golden’ interval?. Eur J Cardiothorac Surg. 2023;63.
10.
Yip H-c. Chiu PW-y. Recent advances in natural orifice transluminal endoscopic surgery †. Eur J Cardiothorac Surg. 2015;49:i25–i30.
11.
Ishihara R, Arima M, Iizuka T, Oyama T, Katada C, Kato M, et al. Endoscopic submucosal dissection/endoscopic mucosal resection guidelines for esophageal cancer. Dig Endosc. 2020;32:452–93.CrossRefPubMed
12.
Ko C-Y, Yao C-C, Li Y-C, Lu L-S, Chou Y-P, Hu M-L, et al. Clinical outcomes of endoscopic submucosal dissection for colorectal neoplasms: a single-center experience in Southern Taiwan. PLoS ONE. 2022;17:e0275723.CrossRefPubMedPubMedCentral
13.
Schwartz LH, Ozsahin M, Zhang GN, Touboul E, De Vataire F, Andolenko P, et al. Synchronous and metachronous head and neck carcinomas. Cancer. 1994;74:1933–38.CrossRefPubMed
14.
Braakhuis BJM, Tabor MP, Kummer JA, Leemans CR, Brakenhoff RH. A genetic explanation of Slaughter’s Concept of Field Cancerization: evidence and clinical Implications1. Cancer Res. 2003;63:1727–30.PubMed
15.
Partridge M, Li SR, Pateromichelakis S, Francis R, Phillips E, Huang XH, et al. Detection of minimal residual cancer to investigate why oral tumors recur despite seemingly adequate treatment. Clin cancer Research: Official J Am Association Cancer Res. 2000;6:2718–25.
16.
Tabor MP, Brakenhoff RH, van Houten VM, Kummer JA, Snel MH, Snijders PJ, et al. Persistence of genetically altered fields in head and neck cancer patients: biological and clinical implications. Clin cancer Research: Official J Am Association Cancer Res. 2001;7:1523–32.
17.
Tsai PC, Ting YC, Hsu PK, Hung JJ, Huang CS, Hsu WH et al. Overall survival for Esophageal Squamous Cell Carcinoma with multiple primary cancers after curative Esophagectomy-A retrospective single-Institution Study. Cancers (Basel). 2022;14.
18.
Otowa Y, Nakamura T, Takiguchi G, Yamamoto M, Kanaji S, Imanishi T, et al. Safety and benefit of curative surgical resection for esophageal squamous cell cancer associated with multiple primary cancers. Eur J Surg Oncol. 2016;42:407–11.CrossRefPubMed
Metadata
Title
Similar survival after endoscopic submucosal dissection and esophagectomy in early esophageal cancer and synchronous or metachronous head and neck cancer
Authors
Ruei-Ti Ke
Yu-Hsin Hsiao
Wei-Chen Tai
Shau-Hsuan Li
Chih-Chien Yao
Kai-Hao Chuang
Hsing-Hua Lai
Yu Chen
Li-Chun Chen
Hung-I Lu
Yen-Hao Chen
Chien-Ming Lo
Publication date
01-12-2024
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2024
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-024-02514-3

Other articles of this Issue 1/2024

Journal of Cardiothoracic Surgery 1/2024 Go to the issue

Case Report

Effective Apixaban removal using hemoadsorption during emergent open-heart surgery: a case report and narrative literature review

Case Report

An innovative reconstruction of an enbloc resected composite giant chest and abdominal wall chondrosarcoma with 3D-composite mesh

Research

New insights and novel perspectives in bileaflet mechanical heart valve prostheses thromboresistance

Case Report

Venovenous extracorporeal membrane oxygenation after cardiac arrest for acute respiratory distress syndrome caused by Legionella: a case report

Research

Risk factors of 30-day and long-term mortality and outcomes in open repair of thoracoabdominal aortic aneurysm

Research

In a porcine model of implantable pacemakers for pediatric unilateral diaphragm paralysis, the phrenic nerve is the best target