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Journal of Cardiothoracic Surgery

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Open Access 01-12-2018 | Research article

Differences of patients’ characteristics in acute type A aortic dissection – surgical data from Belgian and Japanese centers-

Authors: Motohiko Goda, Tomoyuki Minami, Kiyotaka Imoto, Keiji Uchida, Munetaka Masuda, Bart Meuris

Published in: Journal of Cardiothoracic Surgery | Issue 1/2018

Abstract

Background

It is well known that there are major differences between the Japanese and Western population regarding the incidence of ischemic heart disease and stroke. The purpose of this study was to evaluate differences of patients’ characteristics between Belgian and Japanese cohort with acute type A aortic dissection.

Methods

In 487 patients (297 male patients, mean age 61.9 ± 12.2 yrs) who underwent surgery for acute type A aortic dissection, baseline preoperative and intraoperative data were collected. Belgian patients (n = 237) were compared to Japanese patients (n = 250). Clinical data included patient demographics, history, status at presentation, imaging study results and intraoperative findings.

Results

The Japanese cohort had significantly more women (48.8% vs. 28.7%, p < 0.0001), lower BMI (24.2 vs. 26.4, p < 0.0001) and lower prevalence of hypertension (49.2% vs. 65.8%, p = 0.0002). More DeBakey type I dissections and less type III dissections with retrograde extension were reported in Belgium than in Japan (77.2% vs. 48.4%, p < 0.0001, 3.4% vs. 38.7%, p < 0.0001, respectively). More entries were found in the ascending aorta (78.5% vs. 58.5%, p < 0.0001) and aortic arch (24.9% vs. 13.7%, p = 0.0018) in Belgian patients than in Japanese patients, who had more entries in the descending aorta or undetected entries.

Conclusions

In acute type A aortic dissection, Belgian patients reveal striking differences from Japanese patients regarding gender distribution, entry tear location and type of dissection. Japanese women are more likely to develop acute type A aortic dissection than Belgian women. (234 words).

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Title: Differences of patients’ characteristics in acute type A aortic dissection – surgical data from Belgian and Japanese centers-
Authors: Motohiko Goda
Tomoyuki Minami
Kiyotaka Imoto
Keiji Uchida
Munetaka Masuda
Bart Meuris
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Journal of Cardiothoracic Surgery / Issue 1/2018
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-018-0782-x

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Differences of patients’ characteristics in acute type A aortic dissection – surgical data from Belgian and Japanese centers-

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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