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Published in: Journal of Orthopaedic Surgery and Research 1/2018

Open Access 01-12-2018 | Research article

Preoperative dual-energy X-ray absorptiometry and FRAX in patients with lumbar spinal stenosis

Authors: Camilla Bergh, Ann-Charlott Söderpalm, Helena Brisby

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2018

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Abstract

Background

Osteoporosis implies an increased risk of complications after orthopedic surgery. For the mostly elderly group of patients undergoing lumbar spinal stenosis surgery (LSS), it is important to include skeletal health evaluation in the preoperative planning. The aim of this study was to assess spine and femoral neck (FN) bone mineral density (BMD) in LSS patients and to evaluate whether the World Health Organization (WHO) fracture risk assessment tool (FRAX) can identify patients with reduced BMD levels in the spine.

Methods

The study involved 65 LSS patients and 53 patients with hip osteoarthritis (HOA) for comparison. BMD was measured with dual-energy X-ray absorptiometry (DXA) in the lumbar spine in three projections: anterior-posterior (AP), lateral and lateral-mid (the mid-portion of the vertebrae), and FN. The LSS patients filled out the FRAX questionnaire.

Results

In the LSS group, 43% of the women and 8% of the men were classified as being osteoporotic/osteopenic by AP spine measurement. The corresponding proportions using the lateral spine T-score ≤ − 2.5 were 87% and 57%, respectively, and 82% and 53%, respectively, for the FN. The FN BMD T-score was significantly lower in the LSS group compared with the HOA group. The FRAX questionnaire identified 40% of the LSS patients with a moderate/high risk of sustaining an osteoporotic fracture within 10 years, with or without simultaneous FN BMD, while 71% of these patients were classified as being osteoporotic with DXA lateral spine measurement.

Conclusion

It is common with osteoporosis/osteopenia in patients undergoing spine surgery, and the identification may influence the surgical treatment why the evaluation of BMD is important preoperatively. FRAX evaluation could not replace DXA measurement of the spine regarding the identification of osteoporosis patients in the preoperative planning phase.
Literature
1.
go back to reference Weinstein JN, et al. Surgical versus nonoperative treatment for lumbar spinal stenosis four-year results of the Spine Patient Outcomes Research Trial. Spine (Phila Pa 1976). 2010;35(14):1329–38.CrossRef Weinstein JN, et al. Surgical versus nonoperative treatment for lumbar spinal stenosis four-year results of the Spine Patient Outcomes Research Trial. Spine (Phila Pa 1976). 2010;35(14):1329–38.CrossRef
2.
go back to reference Ishimoto Y, et al. Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama spine study. Osteoarthr Cartil. 2012;20(10):1103–8.CrossRef Ishimoto Y, et al. Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama spine study. Osteoarthr Cartil. 2012;20(10):1103–8.CrossRef
3.
go back to reference Kalichman L, et al. Spinal stenosis prevalence and association with symptoms: the Framingham Study. Spine J. 2009;9(7):545–50.CrossRef Kalichman L, et al. Spinal stenosis prevalence and association with symptoms: the Framingham Study. Spine J. 2009;9(7):545–50.CrossRef
4.
go back to reference Jansson KA, et al. Health-related quality of life (EQ-5D) before and one year after surgery for lumbar spinal stenosis. J Bone Joint Surg Br. 2009;91(2):210–6.CrossRef Jansson KA, et al. Health-related quality of life (EQ-5D) before and one year after surgery for lumbar spinal stenosis. J Bone Joint Surg Br. 2009;91(2):210–6.CrossRef
5.
go back to reference Iversen MD, Katz JN. Examination findings and self-reported walking capacity in patients with lumbar spinal stenosis. Phys Ther. 2001;81(7):1296–306.PubMed Iversen MD, Katz JN. Examination findings and self-reported walking capacity in patients with lumbar spinal stenosis. Phys Ther. 2001;81(7):1296–306.PubMed
6.
go back to reference Tomkins-Lane CC, et al. Predictors of walking performance and walking capacity in people with lumbar spinal stenosis, low back pain, and asymptomatic controls. Arch Phys Med Rehabil. 2012;93(4):647–53.CrossRef Tomkins-Lane CC, et al. Predictors of walking performance and walking capacity in people with lumbar spinal stenosis, low back pain, and asymptomatic controls. Arch Phys Med Rehabil. 2012;93(4):647–53.CrossRef
7.
go back to reference Makinen TJ, et al. The incidence of osteopenia and osteoporosis in women with hip osteoarthritis scheduled for cementless total joint replacement. Bone. 2007;40(4):1041–7.CrossRef Makinen TJ, et al. The incidence of osteopenia and osteoporosis in women with hip osteoarthritis scheduled for cementless total joint replacement. Bone. 2007;40(4):1041–7.CrossRef
8.
go back to reference Kanis JA, et al. The diagnosis of osteoporosis. J Bone Miner Res. 1994;9(8):1137–41.CrossRef Kanis JA, et al. The diagnosis of osteoporosis. J Bone Miner Res. 1994;9(8):1137–41.CrossRef
9.
go back to reference Chin DK, et al. Prevalence of osteoporosis in patients requiring spine surgery: incidence and significance of osteoporosis in spine disease. Osteoporos Int. 2007;18(9):1219–24.CrossRef Chin DK, et al. Prevalence of osteoporosis in patients requiring spine surgery: incidence and significance of osteoporosis in spine disease. Osteoporos Int. 2007;18(9):1219–24.CrossRef
10.
go back to reference Dvorak MF, et al. Anterior cervical plate fixation: a biomechanical study to evaluate the effects of plate design, endplate preparation, and bone mineral density. Spine (Phila Pa 1976). 2005;30(3):294–301.CrossRef Dvorak MF, et al. Anterior cervical plate fixation: a biomechanical study to evaluate the effects of plate design, endplate preparation, and bone mineral density. Spine (Phila Pa 1976). 2005;30(3):294–301.CrossRef
11.
go back to reference Reitman CA, Nguyen L, Fogel GR. Biomechanical evaluation of relationship of screw pullout strength, insertional torque, and bone mineral density in the cervical spine. J Spinal Disord Tech. 2004;17(4):306–11.CrossRef Reitman CA, Nguyen L, Fogel GR. Biomechanical evaluation of relationship of screw pullout strength, insertional torque, and bone mineral density in the cervical spine. J Spinal Disord Tech. 2004;17(4):306–11.CrossRef
12.
go back to reference Okuyama K, et al. Influence of bone mineral density on pedicle screw fixation: a study of pedicle screw fixation augmenting posterior lumbar interbody fusion in elderly patients. Spine J. 2001;1(6):402–7.CrossRef Okuyama K, et al. Influence of bone mineral density on pedicle screw fixation: a study of pedicle screw fixation augmenting posterior lumbar interbody fusion in elderly patients. Spine J. 2001;1(6):402–7.CrossRef
13.
go back to reference Andersen T, et al. Fusion mass bone quality after uninstrumented spinal fusion in older patients. Eur Spine J. 2010;19(12):2200–8.CrossRef Andersen T, et al. Fusion mass bone quality after uninstrumented spinal fusion in older patients. Eur Spine J. 2010;19(12):2200–8.CrossRef
14.
go back to reference Aydogan M, et al. The pedicle screw fixation with vertebroplasty augmentation in the surgical treatment of the severe osteoporotic spines. J Spinal Disord Tech. 2009;22(6):444–7.CrossRef Aydogan M, et al. The pedicle screw fixation with vertebroplasty augmentation in the surgical treatment of the severe osteoporotic spines. J Spinal Disord Tech. 2009;22(6):444–7.CrossRef
15.
go back to reference Dipaola CP, et al. Survey of spine surgeons on attitudes regarding osteoporosis and osteomalacia screening and treatment for fractures, fusion surgery, and pseudoarthrosis. Spine J. 2009;9(7):537–44.CrossRef Dipaola CP, et al. Survey of spine surgeons on attitudes regarding osteoporosis and osteomalacia screening and treatment for fractures, fusion surgery, and pseudoarthrosis. Spine J. 2009;9(7):537–44.CrossRef
16.
go back to reference World Helth organization (WHO) study group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1994;843:1–129. World Helth organization (WHO) study group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser. 1994;843:1–129.
17.
go back to reference Rizzoli R, Slosman D, Bonjour JP. The role of dual energy X-ray absorptiometry of lumbar spine and proximal femur in the diagnosis and follow-up of osteoporosis. Am J Med. 1995;98(2A):33S–6S.CrossRef Rizzoli R, Slosman D, Bonjour JP. The role of dual energy X-ray absorptiometry of lumbar spine and proximal femur in the diagnosis and follow-up of osteoporosis. Am J Med. 1995;98(2A):33S–6S.CrossRef
18.
go back to reference Liu G, et al. Effect of osteoarthritis in the lumbar spine and hip on bone mineral density and diagnosis of osteoporosis in elderly men and women. Osteoporos Int. 1997;7(6):564–9.CrossRef Liu G, et al. Effect of osteoarthritis in the lumbar spine and hip on bone mineral density and diagnosis of osteoporosis in elderly men and women. Osteoporos Int. 1997;7(6):564–9.CrossRef
19.
go back to reference Peacock DJ, et al. Lateral bone density measurements in osteoarthritis of the lumbar spine. Ann Rheum Dis. 1996;55(3):196–8.CrossRef Peacock DJ, et al. Lateral bone density measurements in osteoarthritis of the lumbar spine. Ann Rheum Dis. 1996;55(3):196–8.CrossRef
20.
go back to reference Masud T, et al. Effect of spinal osteophytosis on bone mineral density measurements in vertebral osteoporosis. BMJ. 1993;307(6897):172–3.CrossRef Masud T, et al. Effect of spinal osteophytosis on bone mineral density measurements in vertebral osteoporosis. BMJ. 1993;307(6897):172–3.CrossRef
21.
go back to reference Kanis JA, et al. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int. 2008;19(4):385–97.CrossRef Kanis JA, et al. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int. 2008;19(4):385–97.CrossRef
22.
go back to reference Mao SS, et al. Thoracic quantitative computed tomography (QCT) can sensitively monitor bone mineral metabolism: comparison of thoracic QCT vs lumbar QCT and dual-energy X-ray absorptiometry in detection of age-relative change in bone mineral density. Acad Radiol. 2017;24(12):1582–7.CrossRef Mao SS, et al. Thoracic quantitative computed tomography (QCT) can sensitively monitor bone mineral metabolism: comparison of thoracic QCT vs lumbar QCT and dual-energy X-ray absorptiometry in detection of age-relative change in bone mineral density. Acad Radiol. 2017;24(12):1582–7.CrossRef
23.
go back to reference Kanis JA. Diagnosis of osteoporosis and assessment of fracture risk. Lancet. 2002;359(9321):1929–36.CrossRef Kanis JA. Diagnosis of osteoporosis and assessment of fracture risk. Lancet. 2002;359(9321):1929–36.CrossRef
24.
go back to reference Siminoski K, et al. Recommendations for bone mineral density reporting in Canada. Can Assoc Radiol J. 2005;56(3):178–88.PubMed Siminoski K, et al. Recommendations for bone mineral density reporting in Canada. Can Assoc Radiol J. 2005;56(3):178–88.PubMed
25.
go back to reference Kanis JA, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int. 2013;24(1):23–57.CrossRef Kanis JA, et al. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int. 2013;24(1):23–57.CrossRef
26.
go back to reference Andersen T, et al. Degenerative spondylolisthesis is associated with low spinal bone density: a comparative study between spinal stenosis and degenerative spondylolisthesis. Biomed Res Int. 2013;2013:123847.PubMedPubMedCentral Andersen T, et al. Degenerative spondylolisthesis is associated with low spinal bone density: a comparative study between spinal stenosis and degenerative spondylolisthesis. Biomed Res Int. 2013;2013:123847.PubMedPubMedCentral
27.
go back to reference Lee BH, et al. Osteoporotic profiles in elderly patients with symptomatic lumbar spinal canal stenosis. Indian J Orthop. 2012;46(3):279–84.CrossRef Lee BH, et al. Osteoporotic profiles in elderly patients with symptomatic lumbar spinal canal stenosis. Indian J Orthop. 2012;46(3):279–84.CrossRef
28.
go back to reference Popp AW, et al. DensiProbe spine: an intraoperative measurement of bone quality in spinal instrumentation. A clinical feasibility study. Spine J. 2013;13(10):1223–9.CrossRef Popp AW, et al. DensiProbe spine: an intraoperative measurement of bone quality in spinal instrumentation. A clinical feasibility study. Spine J. 2013;13(10):1223–9.CrossRef
29.
go back to reference Ensrud KE. Epidemiology of fracture risk with advancing age. J Gerontol A Biol Sci Med Sci. 2013;68(10):1236–42.CrossRef Ensrud KE. Epidemiology of fracture risk with advancing age. J Gerontol A Biol Sci Med Sci. 2013;68(10):1236–42.CrossRef
Metadata
Title
Preoperative dual-energy X-ray absorptiometry and FRAX in patients with lumbar spinal stenosis
Authors
Camilla Bergh
Ann-Charlott Söderpalm
Helena Brisby
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2018
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/s13018-018-0964-1

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