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Journal of Orthopaedic Surgery and Research
Published in: Journal of Orthopaedic Surgery and Research 1/2015

Open Access 01-12-2015 | Research article

Intermediate-term trends in serum levels of metal ions after hip resurfacing arthroplasty

Authors: Wenxue Jiang, Yanlin Wan, Peng Cui, Xianjia Ning

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2015

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Abstract

Background

The potential risks associated with hip resurfacing arthroplasty (HRA) are controversial and underestimated. The aim of this study was to explore intermediate-term trends for the levels of cobalt (Co), chromium (Cr), and molybdenum (Mo) ions after HRA.

Methods

Forty patients who underwent HRA from October 2005 to December 2010 were recruited to this study. The serum levels of metal ions were examined preoperatively and 3, 12, 24, and 60 months after surgery. Trends and differences in levels of metal ions with respect to sex, operated side, and body mass index (BMI) were analyzed.

Results

There were no significant differences in levels of Cr, Co, and Mo at each time point with respect to sex, operated side, and BMI (p > 0.05). The postoperative levels of Cr, Co, and Mo ions were significantly higher than the preoperative levels across sex, operated side, and BMI groups. Postoperative levels of Cr, Co, and Mo peaked at 12, 24, and 60 months, respectively. Cr levels peaked earlier (at 12 months) in the overweight (BMI ≥25 kg/m2) group compared to the normal-weight group (BMI <25 kg/m2), Co levels (at 12 months) peaked in women compared to men, and Mo levels (at 3 months) peaked in the bilateral HRA group compared to the unilateral HRA group.

Conclusions

Serum levels of Cr, Co, and Mo increased significantly after HRA. Cr levels peaked earlier in the overweight patients, Co levels peaked in women, and Mo levels peaked in patients who underwent bilateral HRA. However, there were no significant differences with respect to sex, operated side, and BMI.
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Metadata
Title
Intermediate-term trends in serum levels of metal ions after hip resurfacing arthroplasty
Authors
Wenxue Jiang
Yanlin Wan
Peng Cui
Xianjia Ning
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2015
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/s13018-015-0335-0

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