Skip to main content
Top
Published in: World Journal of Emergency Surgery 1/2018

Open Access 01-12-2018 | Research article

Effect of resuscitative endovascular balloon occlusion of the aorta in hemodynamically unstable patients with multiple severe torso trauma: a retrospective study

Authors: Hiroyuki Otsuka, Toshiki Sato, Keiji Sakurai, Hiromichi Aoki, Takeshi Yamagiwa, Shinichi Iizuka, Sadaki Inokuchi

Published in: World Journal of Emergency Surgery | Issue 1/2018

Login to get access

Abstract

Background

Although resuscitative endovascular balloon occlusion of the aorta (REBOA) may be effective in trauma management, its effect in patients with severe multiple torso trauma remains unclear.

Methods

We performed a retrospective study to evaluate trauma management with REBOA in hemodynamically unstable patients with severe multiple trauma. Of 5899 severe trauma patients admitted to our hospital between January 2011 and January 2018, we selected 107 patients with severe torso trauma (Injury Severity Score > 16) who displayed persistent hypotension [≥ 2 systolic blood pressure (SBP) values ≤ 90 mmHg] regardless of primary resuscitation. Patients were divided into two groups: trauma management with REBOA (n = 15) and without REBOA (n = 92). The primary endpoint was the effectiveness of trauma management with REBOA with respect to in-hospital mortality. Secondary endpoints included time from arrival to the start of hemostasis. Multivariable logistic regression analysis, adjusted for clinically important variables, was performed to evaluate clinical outcomes.

Results

Trauma management with REBOA was significantly associated with decreased mortality (adjusted odds ratio of survival, 7.430; 95% confidence interval, 1.081–51.062; p = 0.041). The median time (interquartile range) from admission to initiation of hemostasis was not significantly different between the two groups [with REBOA 53.0 (40.0–80.3) min vs. without REBOA 57.0 (35.0–100.0) min ]. The time from arrival to the start of balloon occlusion was 55.7 ± 34.2 min. SBP before insertion of REBOA was 48.2 ± 10.5 mmHg. Total balloon occlusion time was 32.5 ± 18.2 min.

Conclusions

The use of REBOA without a delay in initiating resuscitative hemostasis may improve the outcomes in patients with multiple severe torso trauma. However, optimal use may be essential for success.
Literature
1.
go back to reference Rotondo MF, Schwab CW, McGonigal MD, Phillips GR 3rd, Fruchterman TM, Kauder DR, et al. ‘Damage control’: an approach for improved survival in exsanguinating penetrating abdominal injury. J Trauma. 1993;35:375–82 discussion 382-3.CrossRef Rotondo MF, Schwab CW, McGonigal MD, Phillips GR 3rd, Fruchterman TM, Kauder DR, et al. ‘Damage control’: an approach for improved survival in exsanguinating penetrating abdominal injury. J Trauma. 1993;35:375–82 discussion 382-3.CrossRef
2.
go back to reference Moore EE, Burch JM, Franciose RJ, Offner PJ, Biffl WL. Staged physiologic restoration and damage control surgery. World J Surg. 1998;22:1184–90 discussion 1190-1.CrossRef Moore EE, Burch JM, Franciose RJ, Offner PJ, Biffl WL. Staged physiologic restoration and damage control surgery. World J Surg. 1998;22:1184–90 discussion 1190-1.CrossRef
3.
go back to reference Shapiro MB, Jenkins DH, Schwab CW, Rotondo MF. Damage control: collective review. J Trauma. 2000;49:969–78.CrossRef Shapiro MB, Jenkins DH, Schwab CW, Rotondo MF. Damage control: collective review. J Trauma. 2000;49:969–78.CrossRef
4.
go back to reference Stahel PF, Smith WR, Moore EE. Current trends in resuscitation strategy for the multiply injured patient. Injury. 2009;40:S27–35.CrossRef Stahel PF, Smith WR, Moore EE. Current trends in resuscitation strategy for the multiply injured patient. Injury. 2009;40:S27–35.CrossRef
5.
go back to reference Leidner B, Beckman MO. Standardized whole-body computed tomography as a screening tool in blunt multitrauma patients. Emerg Radiol. 2001;8:20–8.CrossRef Leidner B, Beckman MO. Standardized whole-body computed tomography as a screening tool in blunt multitrauma patients. Emerg Radiol. 2001;8:20–8.CrossRef
6.
go back to reference Ball CG, Kirkpatrick AW, D’Amours SK. The RAPTOR: resuscitation with angiography, percutaneous techniques and operative repair: transforming discipline of trauma surgery. Can J Surg. 2011;54:E3–4.CrossRef Ball CG, Kirkpatrick AW, D’Amours SK. The RAPTOR: resuscitation with angiography, percutaneous techniques and operative repair: transforming discipline of trauma surgery. Can J Surg. 2011;54:E3–4.CrossRef
7.
go back to reference Kinoshita T, Yamakawa K, Matsuda H, Yoshikawa Y, Wada D, Hamasaki T, et al. The survival benefit of a novel trauma workflow that includes immediate whole-body computed tomography, surgery, and interventional radiology, all in one trauma resuscitation room: a retrospective historical control study. Ann Surg. 2017. https://doi.org/10.1097/SLA.0000000000002527. Kinoshita T, Yamakawa K, Matsuda H, Yoshikawa Y, Wada D, Hamasaki T, et al. The survival benefit of a novel trauma workflow that includes immediate whole-body computed tomography, surgery, and interventional radiology, all in one trauma resuscitation room: a retrospective historical control study. Ann Surg. 2017. https://​doi.​org/​10.​1097/​SLA.​0000000000002527​.
8.
go back to reference Morrison JJ, Galgon RE, Jansen JO, Cannon JW, Rasmussen TE, Eliason JL. A systematic review of the use of resuscitative endovascular balloon occlusion of the aorta in the management of hemorrhagic shock. J Trauma Acute Care Surg. 2016;80:324–34.CrossRef Morrison JJ, Galgon RE, Jansen JO, Cannon JW, Rasmussen TE, Eliason JL. A systematic review of the use of resuscitative endovascular balloon occlusion of the aorta in the management of hemorrhagic shock. J Trauma Acute Care Surg. 2016;80:324–34.CrossRef
9.
go back to reference Inoue J, Shiraishi A, Yoshiyuki A, Haruta K, Matsui H, Otomo Y. Resuscitative endovascular balloon occlusion of the aorta might be dangerous in patients with severe torso trauma: a propensity score analysis. J Trauma Acute Care Surg. 2016;80:559–66 discussion 566-7.CrossRef Inoue J, Shiraishi A, Yoshiyuki A, Haruta K, Matsui H, Otomo Y. Resuscitative endovascular balloon occlusion of the aorta might be dangerous in patients with severe torso trauma: a propensity score analysis. J Trauma Acute Care Surg. 2016;80:559–66 discussion 566-7.CrossRef
10.
go back to reference Moore LJ, Martin CD, Harvin JA, Wade CE, Holcomb JB. Resuscitative endovascular balloon occlusion of the aorta for control of noncompressible truncal hemorrhage in the abdomen and pelvis. Am J Surg. 2016;212:1222–30.CrossRef Moore LJ, Martin CD, Harvin JA, Wade CE, Holcomb JB. Resuscitative endovascular balloon occlusion of the aorta for control of noncompressible truncal hemorrhage in the abdomen and pelvis. Am J Surg. 2016;212:1222–30.CrossRef
11.
go back to reference Gamberini E, Coccolini F, Tamagnini B, Martino C, Albarello V, Benni M, et al. Resuscitative endovascular balloon occlusion of the aorta in trauma: a systematic review of the literature. World J Emerg Surg. 2017;12:42.CrossRef Gamberini E, Coccolini F, Tamagnini B, Martino C, Albarello V, Benni M, et al. Resuscitative endovascular balloon occlusion of the aorta in trauma: a systematic review of the literature. World J Emerg Surg. 2017;12:42.CrossRef
12.
go back to reference Norii T, Crandall C, Terasaka Y. Survival of severe blunt trauma patients treated with resuscitative endovascular balloon occlusion of the aorta compared with propensity score-adjusted untreated patients. J Trauma Acute Care Surg. 2015;78:721–8.CrossRef Norii T, Crandall C, Terasaka Y. Survival of severe blunt trauma patients treated with resuscitative endovascular balloon occlusion of the aorta compared with propensity score-adjusted untreated patients. J Trauma Acute Care Surg. 2015;78:721–8.CrossRef
13.
go back to reference Brenner M, Teeter W, Hoehn M, Pasley J, Hu P, Yang S, et al. Use of resuscitative endovascular balloon occlusion of the aorta for proximal aortic control in patients with severe hemorrhage and arrest. JAMA Surg. 2018;153:130–5.CrossRef Brenner M, Teeter W, Hoehn M, Pasley J, Hu P, Yang S, et al. Use of resuscitative endovascular balloon occlusion of the aorta for proximal aortic control in patients with severe hemorrhage and arrest. JAMA Surg. 2018;153:130–5.CrossRef
14.
go back to reference Pieper A, Thony F, Brun J, Rodière M, Boussat B, Arvieux C, et al. Resuscitative endovascular balloon occlusion of the aorta for pelvic blunt trauma and life-threatening hemorrhage: a 20-year experience in a level I trauma center. J Trauma Acute Care Surg. 2018;84:449–53.CrossRef Pieper A, Thony F, Brun J, Rodière M, Boussat B, Arvieux C, et al. Resuscitative endovascular balloon occlusion of the aorta for pelvic blunt trauma and life-threatening hemorrhage: a 20-year experience in a level I trauma center. J Trauma Acute Care Surg. 2018;84:449–53.CrossRef
15.
go back to reference DuBose JJ. How I do it: partial resuscitative endovascular balloon occlusion of the aorta (P-REBOA). J Trauma Acute Care Surg. 2017;83:197–9.CrossRef DuBose JJ. How I do it: partial resuscitative endovascular balloon occlusion of the aorta (P-REBOA). J Trauma Acute Care Surg. 2017;83:197–9.CrossRef
16.
go back to reference Biffl WL, Fox CJ, Moore EE. The role of REBOA in the control of exsanguinating torso hemorrhage. J Trauma Acute Care Surg. 2015;78:1054–8.CrossRef Biffl WL, Fox CJ, Moore EE. The role of REBOA in the control of exsanguinating torso hemorrhage. J Trauma Acute Care Surg. 2015;78:1054–8.CrossRef
17.
go back to reference Johnson MA, Davidson AJ, Russo RM, Ferencz SE, Gotlib O, Rasmussen TE, et al. Small changes, big effects: the hemodynamics of partial and complete aortic occlusion to inform next generation resuscitation techniques and technologies. J Trauma Acute Care Surg. 2017;82:1106–11.CrossRef Johnson MA, Davidson AJ, Russo RM, Ferencz SE, Gotlib O, Rasmussen TE, et al. Small changes, big effects: the hemodynamics of partial and complete aortic occlusion to inform next generation resuscitation techniques and technologies. J Trauma Acute Care Surg. 2017;82:1106–11.CrossRef
18.
go back to reference Romagnoli A, Teeter W, Pasley J, Hu P, Hoehn M, Stein D, et al. Time to aortic occlusion: it’s all about access. J Trauma Acute Care Surg. 2017;83:1161–4.CrossRef Romagnoli A, Teeter W, Pasley J, Hu P, Hoehn M, Stein D, et al. Time to aortic occlusion: it’s all about access. J Trauma Acute Care Surg. 2017;83:1161–4.CrossRef
19.
go back to reference Martinelli T, Thony F, Decléty P, Sengel C, Broux C, Tonetti J, et al. Intra-aortic balloon occlusion to salvage patients with life-threatening hemorrhagic shocks from pelvic fractures. J Trauma. 2010;68:942–8.PubMed Martinelli T, Thony F, Decléty P, Sengel C, Broux C, Tonetti J, et al. Intra-aortic balloon occlusion to salvage patients with life-threatening hemorrhagic shocks from pelvic fractures. J Trauma. 2010;68:942–8.PubMed
20.
go back to reference Champion HR, Sacco WJ, Copes WS, Gann DS, Gennarelli TA, Flanagan ME. A revision of the Trauma Score. J Trauma. 1989;29:623–9.CrossRef Champion HR, Sacco WJ, Copes WS, Gann DS, Gennarelli TA, Flanagan ME. A revision of the Trauma Score. J Trauma. 1989;29:623–9.CrossRef
21.
go back to reference Baker SP, O’Neill B, Haddon W Jr, Long WB. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974;14:187–96.CrossRef Baker SP, O’Neill B, Haddon W Jr, Long WB. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 1974;14:187–96.CrossRef
22.
go back to reference Gruen RL, Brohi K, Schreiber M, Balogh ZJ, Pitt V, Narayan M, et al. Haemorrhage control in severely injured patients. Lancet. 2012;380:1099–108.CrossRef Gruen RL, Brohi K, Schreiber M, Balogh ZJ, Pitt V, Narayan M, et al. Haemorrhage control in severely injured patients. Lancet. 2012;380:1099–108.CrossRef
23.
go back to reference de Munter L, Polinder S, Lansink KW, Cnossen MC, Steyerberg EW. Mortality prediction models in the general trauma population: a systematic review. Injury. 2017;48:221–9.CrossRef de Munter L, Polinder S, Lansink KW, Cnossen MC, Steyerberg EW. Mortality prediction models in the general trauma population: a systematic review. Injury. 2017;48:221–9.CrossRef
24.
go back to reference Ibrahim I, Chor WP, Chue KM, Tan CS, Tan HL, Siddiqui FJ, et al. Is arterial base deficit still a useful prognostic marker in trauma? A systematic review. Am J Emerg Med. 2016;34:626–35.CrossRef Ibrahim I, Chor WP, Chue KM, Tan CS, Tan HL, Siddiqui FJ, et al. Is arterial base deficit still a useful prognostic marker in trauma? A systematic review. Am J Emerg Med. 2016;34:626–35.CrossRef
25.
go back to reference Umebachi R, Taira T, Wakai S, Aoki H, Otsuka H, Nakagawa Y, et al. Measurement of blood lactate, D-dimer, and activated prothrombin time improves prediction of in-hospital mortality in adults blunt trauma. Am J Emerg Med. 2018;36:370–5.CrossRef Umebachi R, Taira T, Wakai S, Aoki H, Otsuka H, Nakagawa Y, et al. Measurement of blood lactate, D-dimer, and activated prothrombin time improves prediction of in-hospital mortality in adults blunt trauma. Am J Emerg Med. 2018;36:370–5.CrossRef
26.
go back to reference Davidson AJ, Russo RM, Reva VA, Brenner ML, Moore LJ, Ball C, et al. The pitfalls of resuscitative endovascular balloon occlusion of the aorta: risk factors and mitigation strategies. J Trauma Acute Care Surg. 2018;84:192–202.CrossRef Davidson AJ, Russo RM, Reva VA, Brenner ML, Moore LJ, Ball C, et al. The pitfalls of resuscitative endovascular balloon occlusion of the aorta: risk factors and mitigation strategies. J Trauma Acute Care Surg. 2018;84:192–202.CrossRef
27.
go back to reference Taylor JR 3rd, Harvin JA, Martin C, Holcomb JB, Moore LJ. Vascular complications from resuscitative endovascular balloon occlusion of the aorta: life over limb? J Trauma Acute Care Surg. 2017;83:S120–3.CrossRef Taylor JR 3rd, Harvin JA, Martin C, Holcomb JB, Moore LJ. Vascular complications from resuscitative endovascular balloon occlusion of the aorta: life over limb? J Trauma Acute Care Surg. 2017;83:S120–3.CrossRef
28.
go back to reference Saito N, Matsumoto H, Yagi T, Hara Y, Hayashida K, Motomura T, et al. Evaluation of the safety and feasibility of resuscitative endovascular balloon occlusion of the aorta. J Trauma Acute Care Surg. 2015;78:897–903 discussion 904.CrossRef Saito N, Matsumoto H, Yagi T, Hara Y, Hayashida K, Motomura T, et al. Evaluation of the safety and feasibility of resuscitative endovascular balloon occlusion of the aorta. J Trauma Acute Care Surg. 2015;78:897–903 discussion 904.CrossRef
29.
go back to reference Teeter WA, Matsumoto J, Idoguchi K, Kon Y, Orita T, Funabiki T, et al. Smaller introducer sheaths for REBOA may be associated with fewer complications. J Trauma Acute Care Surg. 2016;81:1039–45.CrossRef Teeter WA, Matsumoto J, Idoguchi K, Kon Y, Orita T, Funabiki T, et al. Smaller introducer sheaths for REBOA may be associated with fewer complications. J Trauma Acute Care Surg. 2016;81:1039–45.CrossRef
30.
go back to reference Bogert JN, Patel BM, Johnson DJ. Ultrasound optimization for resuscitative endovascular balloon occlusion of the aorta. J Trauma Acute Care Surg. 2017;82(1):204–7.CrossRef Bogert JN, Patel BM, Johnson DJ. Ultrasound optimization for resuscitative endovascular balloon occlusion of the aorta. J Trauma Acute Care Surg. 2017;82(1):204–7.CrossRef
31.
32.
go back to reference Russo RM, Williams TK, Grayson JK, Lamb CM, Cannon JW, Clement NF. Extending the golden hour: partial resuscitative endovascular balloon occlusion of the aorta in a highly lethal swine liver injury model. J Trauma Acute Care Surg. 2016;80:372–8 discussion 378-80.CrossRef Russo RM, Williams TK, Grayson JK, Lamb CM, Cannon JW, Clement NF. Extending the golden hour: partial resuscitative endovascular balloon occlusion of the aorta in a highly lethal swine liver injury model. J Trauma Acute Care Surg. 2016;80:372–8 discussion 378-80.CrossRef
Metadata
Title
Effect of resuscitative endovascular balloon occlusion of the aorta in hemodynamically unstable patients with multiple severe torso trauma: a retrospective study
Authors
Hiroyuki Otsuka
Toshiki Sato
Keiji Sakurai
Hiromichi Aoki
Takeshi Yamagiwa
Shinichi Iizuka
Sadaki Inokuchi
Publication date
01-12-2018
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2018
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/s13017-018-0210-5

Other articles of this Issue 1/2018

World Journal of Emergency Surgery 1/2018 Go to the issue