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Published in: World Journal of Emergency Surgery 1/2018

Open Access 01-12-2018 | Research article

The abdominal wall hernia in cirrhotic patients: a historical challenge

Authors: Giuseppe Salamone, Leo Licari, Giovanni Guercio, Sofia Campanella, Nicolò Falco, Gregorio Scerrino, Sebastiano Bonventre, Girolamo Geraci, Gianfranco Cocorullo, Gaspare Gulotta

Published in: World Journal of Emergency Surgery | Issue 1/2018

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Abstract

Background

The incidence rate of abdominal wall hernia is 20–40% in cirrhotic patients. A surgical approach was originally performed only if complication signs and symptoms occurred. Several recent studies have demonstrated the usefulness of elective surgery. During recent decades, the indications for surgical timing have changed.

Methods

Cirrhotic patients with abdominal hernia who underwent surgical operation for abdominal wall hernia repair at the Policlinico “Paolo Giaccone” at Palermo University Hospital between January 2010 and September 2016 were identified in a prospective database, and the data collected were retrospectively reviewed; patients’ medical and surgical records were collected from charts and surgical and intensive care unit (ICU) registries. Postoperative morbidity was determined through the Clavien-Dindo classification. Cirrhosis severity was estimated by the Child-Pugh-Turcotte (CPT) score and MELD (model of end-stage liver disease) score. Postoperative mortality was considered up to 30 days after surgery. A follow-up period of at least 1 year was used to evaluate hernia recurrence.

Results

The univariate and multivariate analyses demonstrated the unique independent risk factors for the development of postsurgical morbidity (emergency surgery (OR 6.42; p 0.023), CPT class C (OR 3.72; p 0.041), American Society of Anesthesiologists (ASA) score ≥ 3 (OR 4.72; p 0.012) and MELD ≥ 20 (OR 5.64; p 0.009)) and postsurgical mortality (emergency surgery (OR 10.32; p 0.021), CPT class C (OR 5.52; p 0.014), ASA score ≥ 3 (OR 8.65; p 0.018), MELD ≥ 20 (OR 2.15; p 0.02)).

Conclusions

Concerning abdominal wall hernia repair in cirrhotic patients, the worst outcome is associated with emergency surgery and with uncontrolled disease. The correct timing of the surgical operation is elective surgery after ascites drainage and albumin/electrolyte serum level and coagulation alteration correction.
Literature
1.
go back to reference Belghiti J, Durand F. Abdominal wall hernias in the setting of cirrhosis. Semin Liver Dis. 1997;17:219–26.CrossRefPubMed Belghiti J, Durand F. Abdominal wall hernias in the setting of cirrhosis. Semin Liver Dis. 1997;17:219–26.CrossRefPubMed
2.
go back to reference Carbonell AM, Wolfe LG, DeMaria EJ. Poor outcomes in cirrhosis-associated hernia repair: a nationwide cohort study of 32,033 patients. Hernia. 2005;9:353–7.CrossRefPubMed Carbonell AM, Wolfe LG, DeMaria EJ. Poor outcomes in cirrhosis-associated hernia repair: a nationwide cohort study of 32,033 patients. Hernia. 2005;9:353–7.CrossRefPubMed
3.
go back to reference Shlomovitz E, Quan D, Etemad-Rezai R, McAlister VC. Association of recanalization of the left ombilical vein with umbilical hernia in patients with liver disease. Liver Transpl. 2005;11:1298–9.CrossRefPubMed Shlomovitz E, Quan D, Etemad-Rezai R, McAlister VC. Association of recanalization of the left ombilical vein with umbilical hernia in patients with liver disease. Liver Transpl. 2005;11:1298–9.CrossRefPubMed
4.
go back to reference Garrison RN, Cryer HM, Howard DA, Polk HC. Classification of risk factors for abdominal operations in patients with hepatic cirrhosis. Ann Surg. 1984;199:648–55.CrossRefPubMedPubMedCentral Garrison RN, Cryer HM, Howard DA, Polk HC. Classification of risk factors for abdominal operations in patients with hepatic cirrhosis. Ann Surg. 1984;199:648–55.CrossRefPubMedPubMedCentral
5.
go back to reference Leonetti JP, Aranha GV, Wilkinson WA, et al. Umbilical herniorrhaphy in cirrhotic patients. Arch Surg. 1984;119:442–5.CrossRefPubMed Leonetti JP, Aranha GV, Wilkinson WA, et al. Umbilical herniorrhaphy in cirrhotic patients. Arch Surg. 1984;119:442–5.CrossRefPubMed
6.
7.
go back to reference Arroyo A, García P, Pérez F, et al. Randomized clinical trial comparing suture and mesh repair of umbilical hernia in adults. Br J Surg. 2001;88:1321–3.CrossRefPubMed Arroyo A, García P, Pérez F, et al. Randomized clinical trial comparing suture and mesh repair of umbilical hernia in adults. Br J Surg. 2001;88:1321–3.CrossRefPubMed
8.
go back to reference Gray SH, Vick CC, Graham LA, et al. Umbilical herniorrhapy in cirrhosis: improved outcomes with elective repair. J Gastrointest Surg. 2008;12:675–81.CrossRefPubMed Gray SH, Vick CC, Graham LA, et al. Umbilical herniorrhapy in cirrhosis: improved outcomes with elective repair. J Gastrointest Surg. 2008;12:675–81.CrossRefPubMed
9.
go back to reference Coelho JCU, Claus CMP, Campos ACL, et al. Umbilical hernia in patients with liver cirrhosis: a surgical challenge. World J Gastrointest Surg. 2016;8(7):476–82.CrossRefPubMedPubMedCentral Coelho JCU, Claus CMP, Campos ACL, et al. Umbilical hernia in patients with liver cirrhosis: a surgical challenge. World J Gastrointest Surg. 2016;8(7):476–82.CrossRefPubMedPubMedCentral
10.
go back to reference Andraus W, Sepulveda A, Pinheiro RS, et al. Management of uncommon hernias in cirrhotic patients. Transplant Proc. 2010;42:1724–8.CrossRefPubMed Andraus W, Sepulveda A, Pinheiro RS, et al. Management of uncommon hernias in cirrhotic patients. Transplant Proc. 2010;42:1724–8.CrossRefPubMed
11.
go back to reference Park JK, Lee SH, Yoon WJ, et al. Evaluation of hernia repair operation in child-turcotte-pugh class c cirrhosis and refractory ascites. J Gastroenterol Hepatol. 2007;22:377–82.CrossRefPubMed Park JK, Lee SH, Yoon WJ, et al. Evaluation of hernia repair operation in child-turcotte-pugh class c cirrhosis and refractory ascites. J Gastroenterol Hepatol. 2007;22:377–82.CrossRefPubMed
12.
go back to reference Pugh RN, Murray-Lyon IM, Dawson JL, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60:646–9.CrossRefPubMed Pugh RN, Murray-Lyon IM, Dawson JL, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60:646–9.CrossRefPubMed
13.
go back to reference Kamath PS, Wiesner RH, Malinchoc M, et al. A model to predict survival in patients with end-stage liver disease. Hepatology. 2001;33:464–70.CrossRefPubMed Kamath PS, Wiesner RH, Malinchoc M, et al. A model to predict survival in patients with end-stage liver disease. Hepatology. 2001;33:464–70.CrossRefPubMed
14.
go back to reference Green SB. How many subjects does it take to do a regression analysis? Multivar Behav Res. 1991;26:499–510.CrossRef Green SB. How many subjects does it take to do a regression analysis? Multivar Behav Res. 1991;26:499–510.CrossRef
15.
go back to reference McKay A, Dixon E, Bathe O, Sutherland F. Umbilical hernia repair in the presence of cirrhosis and ascites: results of a survey and review of the literature. Hernia. 2009;13(5):461–8.CrossRefPubMed McKay A, Dixon E, Bathe O, Sutherland F. Umbilical hernia repair in the presence of cirrhosis and ascites: results of a survey and review of the literature. Hernia. 2009;13(5):461–8.CrossRefPubMed
16.
go back to reference Belyansky I, Tsirline VB, Klima DA, et al. Prospective, comparative study of postoperative quality of life in tep, tapp, and modified lichtenstein repairs. Ann Surg. 2011;254:709–14. Discussion 714–705CrossRefPubMed Belyansky I, Tsirline VB, Klima DA, et al. Prospective, comparative study of postoperative quality of life in tep, tapp, and modified lichtenstein repairs. Ann Surg. 2011;254:709–14. Discussion 714–705CrossRefPubMed
17.
go back to reference Hansen JB, Thulstrup AM, Vilstup H, Sørensen HT. Danish nationwide cohort study of postoperative death in patients with liver cirrhosis undergoing hernia repair. Br J Surg. 2002;89:805–6.CrossRefPubMed Hansen JB, Thulstrup AM, Vilstup H, Sørensen HT. Danish nationwide cohort study of postoperative death in patients with liver cirrhosis undergoing hernia repair. Br J Surg. 2002;89:805–6.CrossRefPubMed
19.
go back to reference Eker HH, van Ramshorst GH, de Goede B, et al. A prospective study on elective umbilical hernia repair in patients with liver cirrhosis and ascites. Surgery. 2011;150:542–6.CrossRefPubMed Eker HH, van Ramshorst GH, de Goede B, et al. A prospective study on elective umbilical hernia repair in patients with liver cirrhosis and ascites. Surgery. 2011;150:542–6.CrossRefPubMed
20.
go back to reference Hur YH, Kim JC, Kim DY, Kim SK, Park CY. Inguinal hernia repair in patients with liver cirrhosis accompanied by ascites. J Korean Surg Soc. 2011;80(6):420–5.CrossRefPubMedPubMedCentral Hur YH, Kim JC, Kim DY, Kim SK, Park CY. Inguinal hernia repair in patients with liver cirrhosis accompanied by ascites. J Korean Surg Soc. 2011;80(6):420–5.CrossRefPubMedPubMedCentral
21.
go back to reference Farnsworth N, Fagan SP, Berger DH, Awad SS. Child-Turcotte-Pugh versus MELD score as a predictor of outcome after elective and emergent surgery in cirrhotic patients. Am J Surg. 2004;188:580–3.CrossRefPubMed Farnsworth N, Fagan SP, Berger DH, Awad SS. Child-Turcotte-Pugh versus MELD score as a predictor of outcome after elective and emergent surgery in cirrhotic patients. Am J Surg. 2004;188:580–3.CrossRefPubMed
22.
go back to reference Befeler AS, Palmer DE, Hoffman M, et al. The safety of intra-abdominal surgery in patients with cirrhosis: model for end-stage liver disease score is superior to Child-Turcotte-Pugh classification in predicting outcome. Arch Surg. 2005;140:650–4. discussion 655CrossRefPubMed Befeler AS, Palmer DE, Hoffman M, et al. The safety of intra-abdominal surgery in patients with cirrhosis: model for end-stage liver disease score is superior to Child-Turcotte-Pugh classification in predicting outcome. Arch Surg. 2005;140:650–4. discussion 655CrossRefPubMed
23.
go back to reference Teh SH, Nagorney DM, Stevens SR, et al. Risk factors for mortality after surgery in patients with cirrhosis. Gastroenterology. 2007;132:1261–9.CrossRefPubMed Teh SH, Nagorney DM, Stevens SR, et al. Risk factors for mortality after surgery in patients with cirrhosis. Gastroenterology. 2007;132:1261–9.CrossRefPubMed
24.
go back to reference Arif R, Seppelt P, Schwill S, et al. Predictive risk factors for patients with cirrhosis undergoing heart surgery. Ann Thorac Surg. 2012;94:1947–52.CrossRefPubMed Arif R, Seppelt P, Schwill S, et al. Predictive risk factors for patients with cirrhosis undergoing heart surgery. Ann Thorac Surg. 2012;94:1947–52.CrossRefPubMed
25.
go back to reference Neeff H, Mariaskin D, Spangenberg HC, et al. Perioperative mortality after non-hepatic general surgery in patients with liver cirrhosis: an analysis of 138 operations in the 2000s using child and meld scores. J Gastrointest Surg. 2011;15:1–11.CrossRefPubMed Neeff H, Mariaskin D, Spangenberg HC, et al. Perioperative mortality after non-hepatic general surgery in patients with liver cirrhosis: an analysis of 138 operations in the 2000s using child and meld scores. J Gastrointest Surg. 2011;15:1–11.CrossRefPubMed
26.
go back to reference Maniatis AG, Hunt CM. Therapy for spontaneous umbilical hernia rupture. Am J Gastroenterol. 1995;90:310–2.PubMed Maniatis AG, Hunt CM. Therapy for spontaneous umbilical hernia rupture. Am J Gastroenterol. 1995;90:310–2.PubMed
Metadata
Title
The abdominal wall hernia in cirrhotic patients: a historical challenge
Authors
Giuseppe Salamone
Leo Licari
Giovanni Guercio
Sofia Campanella
Nicolò Falco
Gregorio Scerrino
Sebastiano Bonventre
Girolamo Geraci
Gianfranco Cocorullo
Gaspare Gulotta
Publication date
01-12-2018
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2018
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/s13017-018-0196-z

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