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World Journal of Emergency Surgery
Published in: World Journal of Emergency Surgery 1/2016

Open Access 01-12-2016 | Research article

International normalized ratio and serum C-reactive protein are feasible markers to predict complicated appendicitis

Authors: Maru Kim, Sung-Jeep Kim, Hang Joo Cho

Published in: World Journal of Emergency Surgery | Issue 1/2016

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Abstract

Background

Diagnostic approach for complicated appendicitis is still controversial. We planned this study to analyze preoperative laboratory markers that may predict complications of appendicitis.

Methods

Patients who underwent appendectomy were retrospectively recruited. They were divided into complicated appendicitis and non-complicated appendicitis groups and their preoperative laboratory results were reviewed.

Results

A total of 234 patients were included. Elevated international normalized ratio (INR) and serum C-reactive protein (CRP) were associated with complicated appendicitis (p = 0.001). On ROC curve analysis, area under the curve (AUC) of CRP and INR were 0.796 and 0.723, respectively.

Conclusions

INR and CRP increased significantly in patients with complicated appendicitis. Further studies evaluating INR and CRP in patients undergoing conservative management for appendicitis are required.
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Metadata
Title
International normalized ratio and serum C-reactive protein are feasible markers to predict complicated appendicitis
Authors
Maru Kim
Sung-Jeep Kim
Hang Joo Cho
Publication date
01-12-2016
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2016
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/s13017-016-0081-6

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