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Radiation Oncology
Published in: Radiation Oncology 1/2014

Open Access 01-12-2014 | Case report

A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy

Authors: Gen Futamura, Shinji Kawabata, Hiroyuki Siba, Toshihiko Kuroiwa, Minoru Suzuki, Natsuko Kondo, Koji Ono, Yoshinori Sakurai, Minoru Tanaka, Tomoki Todo, Shin-Ichi Miyatake

Published in: Radiation Oncology | Issue 1/2014

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Abstract

We treated a 54-year-old Japanese female with a recurrent radiation-induced osteosarcoma arising from left occipital skull, by reactor-based boron neutron capture therapy (BNCT). Her tumor grew rapidly with subcutaneous and epidural extension. She eventually could not walk because of cerebellar ataxia. The tumor was inoperable and radioresistant. BNCT showed a marked initial therapeutic effect: the subcutaneous/epidural tumor reduced without radiation damage of the scalp except hair loss and the patient could walk again only 3 weeks after BNCT. BNCT seems to be a safe and very effective modality in the management of radiation-induced osteosarcomas that are not eligible for operation and other treatment modalities.
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Metadata
Title
A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy
Authors
Gen Futamura
Shinji Kawabata
Hiroyuki Siba
Toshihiko Kuroiwa
Minoru Suzuki
Natsuko Kondo
Koji Ono
Yoshinori Sakurai
Minoru Tanaka
Tomoki Todo
Shin-Ichi Miyatake
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2014
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/s13014-014-0237-z

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